Reactome | CTSC [endoplasmic reticulum-Golgi intermediate compartment membrane]

CTSC [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-BTA-5689725

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Synonyms

(Glc)3(GlcNAc)2(Man)9-CTSC, F1N455

Locations in the PathwayBrowser

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Metabolism of proteins (Bos taurus)

- Post-translational protein modification (Bos taurus)
  - Asparagine N-linked glycosylation (Bos taurus)
    - Transport to the Golgi and subsequent modification (Bos taurus)
      - ER to Golgi Anterograde Transport (Bos taurus)
        
        COPII-mediated vesicle transport (Bos taurus)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
        
        glycosylated LMAN cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
        
        CTSC [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)

Vesicle-mediated transport (Bos taurus)

- Membrane Trafficking (Bos taurus)
  - ER to Golgi Anterograde Transport (Bos taurus)
    - COPII-mediated vesicle transport (Bos taurus)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
        
        glycosylated LMAN cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
        
        CTSC [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:F1N455

Gene Names

CTSC

Reference Genes

ENSEMBL:ENSBTAG00000011100.5

Other Identifiers

352958

GO:0001913

GO:0002376

GO:0003824

GO:0004197

GO:0004252

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005737

GO:0005764

GO:0005773

GO:0005813

GO:0005815

GO:0005856

GO:0006508

GO:0006915

GO:0006954

GO:0008233

GO:0008234

GO:0008239

GO:0012501

GO:0016505

GO:0016787

GO:0023052

GO:0030163

GO:0031642

GO:0043226

GO:0043231

GO:0048856

GO:0050877

GO:0051603

GO:0098772

GO:0140096

GO:1903980

GO:2001235

Participates

as a member of

glycosylated LMAN cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)

Other forms of this molecule

CTSC [lysosomal lumen]

CTSC [extracellular region]

CTSC [azurophil granule lumen]

CTSC [COPII-coated ER to Golgi transport vesicle]

CTSC [endoplasmic reticulum lumen]

Inferred From

(Glc)3(GlcNAc)2(Man)9-CTSC [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

Modified Residues

Name

N4-(N-acetylamino)glucosyl-L-asparagine (N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue (ChEBI:59084)) at unknown position

Modification

N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-yl group (ChEBI:59084)

PsiMod Name

N4-(N-acetylamino)glucosyl-L-asparagine

PsiMod Definition

A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.

Cross References

OpenTargets

ENSG00000109861

Ensembl

ENSBTAP00000014735, ENSBTAG00000011100, ENSBTAT00000014735

VGNC

27814