Reactome | LMAN2 [endoplasmic reticulum membrane]

LMAN2 [endoplasmic reticulum membrane]

Stable Identifier

R-BTA-5689466

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

endoplasmic reticulum membrane

Synonyms

LMAN2, A6QP36

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Bos taurus)

- Post-translational protein modification (Bos taurus)
  - Asparagine N-linked glycosylation (Bos taurus)
    - Transport to the Golgi and subsequent modification (Bos taurus)
      - ER to Golgi Anterograde Transport (Bos taurus)
        
        COPII-mediated vesicle transport (Bos taurus)
        
        Inner coat assembly and cargo binding (Bos taurus)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        Loss of SAR1B GTPase (Bos taurus)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Bos taurus)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        SEC31:SEC13 and v-SNARE recruitment (Bos taurus)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        Vesicle budding (Bos taurus)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        Cargo concentration in the ER (Bos taurus)
        
        Inner coat assembly and cargo binding (Bos taurus)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family proteins bind glycosylated cargo (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)

Vesicle-mediated transport (Bos taurus)

- Membrane Trafficking (Bos taurus)
  - ER to Golgi Anterograde Transport (Bos taurus)
    - COPII-mediated vesicle transport (Bos taurus)
      - Inner coat assembly and cargo binding (Bos taurus)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
      - Loss of SAR1B GTPase (Bos taurus)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
      - SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Bos taurus)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
      - SEC31:SEC13 and v-SNARE recruitment (Bos taurus)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
      - Vesicle budding (Bos taurus)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
    - Cargo concentration in the ER (Bos taurus)
      - Inner coat assembly and cargo binding (Bos taurus)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
      - LMAN family proteins bind glycosylated cargo (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)
        
        LMAN2 [endoplasmic reticulum membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:A6QP36

Gene Names

LMAN2

Reference Genes

BioGPS Gene:790870 LMAN2

ENSEMBL:ENSBTAG00000008034.5

KEGG Gene (Bos taurus):790870 LMAN2

Monarch:790870 LMAN2

NCBI Gene:790870 LMAN2

Reference Transcript

RefSeq:NM_001101309.1 LMAN2

Other Identifiers

790870

GO:0000139

GO:0005537

GO:0005576

GO:0005615

GO:0005783

GO:0005789

GO:0005793

GO:0005794

GO:0005886

GO:0006888

GO:0006890

GO:0009986

GO:0016020

GO:0016192

GO:0030134

GO:0030246

GO:0031072

GO:0031410

GO:0043226

GO:0050766

Participates

as a candidate of

LMAN family receptors [endoplasmic reticulum membrane] (Bos taurus)

Other forms of this molecule

LMAN2 [endoplasmic reticulum-Golgi intermediate compartment membrane]

LMAN2 [ER to Golgi transport vesicle membrane]

Inferred From

LMAN2 [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_001094779.1

OpenTargets

ENSG00000169223

Ensembl

ENSBTAT00000010569, ENSBTAP00000010569, ENSBTAG00000008034

VGNC

30920

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