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Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane]
Stable Identifier
R-BTA-5654199
Type
Complex
Species
Bos taurus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Bos taurus)
Intracellular signaling by second messengers (Bos taurus)
PIP3 activates AKT signaling (Bos taurus)
Negative regulation of the PI3K/AKT network (Bos taurus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
Activator:PI3K [plasma membrane] (Bos taurus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Bos taurus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
Activator:PI3K [plasma membrane] (Bos taurus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Bos taurus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by FGFR (Bos taurus)
Signaling by FGFR3 (Bos taurus)
Downstream signaling of activated FGFR3 (Bos taurus)
PI-3K cascade:FGFR3 (Bos taurus)
Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Bos taurus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Bos taurus)
Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Bos taurus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Bos taurus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Bos taurus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Bos taurus)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Bos taurus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Activated FGFR3:p-FRS2:p-PTPN11 [plasma membrane]
(Bos taurus)
GRB2:GAB1:PIK3R1 [cytosol]
(Bos taurus)
Participates
as an input of
Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Bos taurus)
as an output of
Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Bos taurus)
as a component of
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Bos taurus)
Inferred From
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane]
(Homo sapiens)
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