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Activated FGFR4 [plasma membrane]
Stable Identifier
R-BTA-5654158
Type
Set [DefinedSet]
Species
Bos taurus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Bos taurus)
Intracellular signaling by second messengers (Bos taurus)
PIP3 activates AKT signaling (Bos taurus)
Negative regulation of the PI3K/AKT network (Bos taurus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
Activator:PI3K [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
Activator:PI3K [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
RAS GEFs promote RAS nucleotide exchange (Bos taurus)
RAS GEFs [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:SOS1 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS3 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Bos taurus)
Activated FGFR4:pY-SHC1 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by FGFR (Bos taurus)
Signaling by FGFR4 (Bos taurus)
Downstream signaling of activated FGFR4 (Bos taurus)
FRS-mediated FGFR4 signaling (Bos taurus)
Activated FGFR4 binds FRS2 (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4 binds FRS3 (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:FRS3 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4 phosphorylates FRS2 (Bos taurus)
Activated FGFR4:FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-8T-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4 phosphorylates FRS3 (Bos taurus)
Activated FGFR4:FRS3 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS3 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4 phosphorylates PPTN11 (Bos taurus)
Activated FGFR4:p-FRS:PTPN11 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS3 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS:p-PTPN11 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS3 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS bind to PPTN11 (Bos taurus)
Activated FGFR4:p-FRS [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS3 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS:PTPN11 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS3 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS binds GRB2:SOS1 (Bos taurus)
Activated FGFR4:p-FRS [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS3 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:SOS1 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS3 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:SOS1 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS3 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
Activated FGFR4:p-FRS:p-PTPN11 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS3 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
PI-3K cascade:FGFR4 (Bos taurus)
Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Bos taurus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA (Bos taurus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Phospholipase C-mediated cascade; FGFR4 (Bos taurus)
Activated FGFR4 binds PLCG1 (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
activated FGFR4:PLCG1 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4 phosphorylates PLCG1 (Bos taurus)
activated FGFR4:PLCG1 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
p-4Y-PLCG1 dissociates from activated FGFR4 (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
SHC-mediated cascade:FGFR4 (Bos taurus)
Activated FGFR4 binds SHC1 (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:SHC1 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4 phosphorylates SHC1 (Bos taurus)
Activated FGFR4:SHC1 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:pY-SHC1 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-SHC1 binds GRB2:SOS1 (Bos taurus)
Activated FGFR4:pY-SHC1 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Bos taurus)
Activated FGFR4:pY-SHC1 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Bos taurus)
Activated FGFR4:pY-SHC1 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Negative regulation of FGFR4 signaling (Bos taurus)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Bos taurus)
Activated FGFR4:FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-8T-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
CBL ubiquitinates FRS2 and FGFR4 (Bos taurus)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Ub-Activated FGFR4 complex:Ub-p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
p-CBL:GRB2 binds p-FRS2:activated FGFR4 (Bos taurus)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4 [plasma membrane] (Bos taurus)
Participants
members
Activated FGFR4 homodimer [plasma membrane]
(Bos taurus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane]
(Bos taurus)
Participates
as an input of
Activated FGFR4 binds FRS3 (Bos taurus)
Activated FGFR4 binds FRS2 (Bos taurus)
Activated FGFR4 binds PLCG1 (Bos taurus)
Activated FGFR4 binds SHC1 (Bos taurus)
as a component of
Activated FGFR4:FRS3 [plasma membrane] (Bos taurus)
Activated FGFR4:p-8T-FRS2 [plasma membrane] (Bos taurus)
Activated FGFR4:FRS2 [plasma membrane] (Bos taurus)
activated FGFR4:PLCG1 [plasma membrane] (Bos taurus)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Bos taurus)
Activated FGFR4:SHC1 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS3 [plasma membrane] (Bos taurus)
Activated FGFR4:pY-SHC1 [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS2 [plasma membrane] (Bos taurus)
as an output of
p-4Y-PLCG1 dissociates from activated FGFR4 (Bos taurus)
Inferred From
Activated FGFR4 [plasma membrane]
(Homo sapiens)
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