MTFMT formylates methionyl-tRNA

Stable Identifier
R-BTA-5432520
Type
Reaction [transition]
Species
Bos taurus
Compartment
mitochondrial matrix
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
MTFMT formylates methionyl-tRNA

The mitochondrial enzyme MTFMT (methionyl-tRNA formyltransferase, methionyl-tRNA transformylase, FMT, FMT1) transfers a formyl group from 10-formyltetrahydrofolate (10-formyl-THF) to the amino group of methionyl-tRNA in a portion of the methionyl-tRNAs in the matrix (Takeuchi et al. 1997, Takeuchi et al. 1998).

Literature References
PubMed ID Title Journal Year
9614118 Mammalian mitochondrial methionyl-tRNA transformylase from bovine liver. Purification, characterization, and gene structure

Spremulli, LL, Takeuchi, N, Omori, A, Watanabe, K, Kawakami, M, Ueda, T

J. Biol. Chem. 1998
9832609 Expression and characterization of bovine mitochondrial methionyl-tRNA transformylase

Takeuchi, N, Watanabe, K, Ueda, T

J. Biochem. 1998
9586066 Mitochondrial methionyl-tRNA transformylase from bovine liver

Spremulli, LL, Takeuchi, N, Watanabe, K, Kawakami, M, Ueda, T

Nucleic Acids Symp. Ser. 1997
Participants
Input
Output
Catalyst Activity

methionyl-tRNA formyltransferase activity of MTFMT [mitochondrial matrix]

Physical Entity
MTFMT [mitochondrial matrix] (Bos taurus)
Activity
methionyl-tRNA formyltransferase activity (GO:0004479)
Orthologous Events
MTFMT formylates methionyl-tRNA (Homo sapiens)
Authored
May, B  (2014-05-09)
Reviewed
Chrzanowska-Lightowlers, ZM  (2014-08-29)
Spremulli, LL  (2014-09-20)
Created
May, B  (2014-05-11)
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