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LIG1 [nucleoplasm]
Stable Identifier
R-BTA-53787
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
LIG1, A0A3S5ZPU0
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
S Phase (Bos taurus)
Synthesis of DNA (Bos taurus)
DNA strand elongation (Bos taurus)
Lagging Strand Synthesis (Bos taurus)
Processive synthesis on the lagging strand (Bos taurus)
Joining of adjacent Okazaki fragments (Bos taurus)
LIG1 [nucleoplasm] (Bos taurus)
Chromosome Maintenance (Bos taurus)
Telomere Maintenance (Bos taurus)
Extension of Telomeres (Bos taurus)
Telomere C-strand (Lagging Strand) Synthesis (Bos taurus)
Processive synthesis on the C-strand of the telomere (Bos taurus)
Joining of adjacent Okazaki fragments of the C-strand (Bos taurus)
LIG1 [nucleoplasm] (Bos taurus)
DNA Repair (Bos taurus)
Base Excision Repair (Bos taurus)
Resolution of Abasic Sites (AP sites) (Bos taurus)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Bos taurus)
PCNA-Dependent Long Patch Base Excision Repair (Bos taurus)
LIG1 binds APEX1 and PCNA at SSB (Bos taurus)
LIG1 [nucleoplasm] (Bos taurus)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Bos taurus)
LIG1 [nucleoplasm] (Bos taurus)
LIG1 bound to APEX1 and PCNA ligates SSB (Bos taurus)
LIG1 [nucleoplasm] (Bos taurus)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Bos taurus)
LIG1 [nucleoplasm] (Bos taurus)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Bos taurus)
LIG1 [nucleoplasm] (Bos taurus)
POLB-Dependent Long Patch Base Excision Repair (Bos taurus)
LIG1 binds POLB at long-patch BER site (Bos taurus)
LIG1 [nucleoplasm] (Bos taurus)
LIG1:POLB:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Bos taurus)
LIG1 [nucleoplasm] (Bos taurus)
LIG1 bound to POLB ligates SSB (Bos taurus)
LIG1 [nucleoplasm] (Bos taurus)
LIG1:POLB:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Bos taurus)
LIG1 [nucleoplasm] (Bos taurus)
LIG1:POLB:dsDNA [nucleoplasm] (Bos taurus)
LIG1 [nucleoplasm] (Bos taurus)
Mismatch Repair (Bos taurus)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) (Bos taurus)
DNA ligase I ligates single stranded nick in double stranded DNA (Bos taurus)
LIG1 [nucleoplasm] (Bos taurus)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) (Bos taurus)
DNA ligase I ligates single stranded nick in double stranded DNA (Bos taurus)
LIG1 [nucleoplasm] (Bos taurus)
Nucleotide Excision Repair (Bos taurus)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Bos taurus)
Gap-filling DNA repair synthesis and ligation in TC-NER (Bos taurus)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Bos taurus)
LIG1,LIG3:XRCC1 [nucleoplasm] (Bos taurus)
LIG1 [nucleoplasm] (Bos taurus)
DNA Replication (Bos taurus)
Synthesis of DNA (Bos taurus)
DNA strand elongation (Bos taurus)
Lagging Strand Synthesis (Bos taurus)
Processive synthesis on the lagging strand (Bos taurus)
Joining of adjacent Okazaki fragments (Bos taurus)
LIG1 [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:A0A3S5ZPU0
Gene Names
LIG1
Reference Genes
ENSEMBL:ENSBTAG00000014595.6
ENSEMBL:ENSBTAG00000014595.7 LIG1
Other Identifiers
100124507
GO:0000166
GO:0000278
GO:0003677
GO:0003824
GO:0003909
GO:0003910
GO:0005524
GO:0005634
GO:0005654
GO:0005739
GO:0006260
GO:0006266
GO:0006273
GO:0006281
GO:0006284
GO:0006310
GO:0006974
GO:0016874
GO:0031090
GO:0043226
GO:0043231
GO:0071897
GO:0140097
GO:1903461
Participates
as a component of
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Bos taurus)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Bos taurus)
LIG1:POLB:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Bos taurus)
LIG1:POLB:dsDNA [nucleoplasm] (Bos taurus)
as an input of
LIG1 binds APEX1 and PCNA at SSB (Bos taurus)
LIG1 binds POLB at long-patch BER site (Bos taurus)
as a member of
LIG1,LIG3:XRCC1 [nucleoplasm] (Bos taurus)
Inferred From
LIG1 [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000105486
Ensembl
ENSBTAP00000031866
,
ENSBTAG00000014595
,
ENSBTAT00000031920
VGNC
30882
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