Reactome | MRPS18A [mitochondrial inner membrane]

MRPS18A [mitochondrial inner membrane]

Stable Identifier

R-BTA-5368200

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

mitochondrial inner membrane

Synonyms

MRPS18A, F1MJC2

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Bos taurus)

- Translation (Bos taurus)
  - Mitochondrial translation (Bos taurus)
    - Mitochondrial translation elongation (Bos taurus)
      - 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Bos taurus)
        
        55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Bos taurus)
        
        55S ribosome [mitochondrial inner membrane] (Bos taurus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A [mitochondrial inner membrane] (Bos taurus)
        
        55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Bos taurus)
        
        55S ribosome [mitochondrial inner membrane] (Bos taurus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A [mitochondrial inner membrane] (Bos taurus)
    - Mitochondrial translation termination (Bos taurus)
      - 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Bos taurus)
        
        55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Bos taurus)
        
        55S ribosome [mitochondrial inner membrane] (Bos taurus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A [mitochondrial inner membrane] (Bos taurus)
        
        55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Bos taurus)
        
        55S ribosome [mitochondrial inner membrane] (Bos taurus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A [mitochondrial inner membrane] (Bos taurus)
      - Hydrolysis of GTP and dissociation of 28S and 39S subunits (Bos taurus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A [mitochondrial inner membrane] (Bos taurus)
        
        55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Bos taurus)
        
        55S ribosome [mitochondrial inner membrane] (Bos taurus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A [mitochondrial inner membrane] (Bos taurus)
      - MRRF binds 55S ribosome:mRNA:tRNA (Bos taurus)
        
        55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Bos taurus)
        
        55S ribosome [mitochondrial inner membrane] (Bos taurus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A [mitochondrial inner membrane] (Bos taurus)
        
        55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Bos taurus)
        
        55S ribosome [mitochondrial inner membrane] (Bos taurus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A [mitochondrial inner membrane] (Bos taurus)
      - MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Bos taurus)
        
        55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] (Bos taurus)
        
        55S ribosome [mitochondrial inner membrane] (Bos taurus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A [mitochondrial inner membrane] (Bos taurus)
        
        55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Bos taurus)
        
        55S ribosome [mitochondrial inner membrane] (Bos taurus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Bos taurus)
        
        MRPS18A [mitochondrial inner membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:F1MJC2

Gene Names

MRPS18A

Reference Genes

ENSEMBL:ENSBTAG00000025571.5

Other Identifiers

614102

GO:0003723

GO:0003735

GO:0005198

GO:0005739

GO:0005763

GO:0005840

GO:0006412

GO:0043226

GO:0070181

GO:1990904

Participates

as a member of

MRPS18A,B,C [mitochondrial inner membrane] (Bos taurus)

Inferred From

MRPS18A [mitochondrial inner membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000096080

Ensembl

ENSBTAP00000051782, ENSBTAT00000056429, ENSBTAG00000025571

VGNC

31658