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phospho-IRF7 [cytosol]
Stable Identifier
R-BTA-450318
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
p-S477,S479-IRF7, A0A3Q1MWF9
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Innate Immune System (Bos taurus)
Cytosolic sensors of pathogen-associated DNA (Bos taurus)
DEx/H-box helicases activate type I IFN and inflammatory cytokines production (Bos taurus)
p-IRF7:p-IRF7 translocates to the nucleus (Bos taurus)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Bos taurus)
TRAF3-dependent IRF activation pathway (Bos taurus)
Dimerization of Phospho IRF3 or phospho IRF7 (Bos taurus)
IRF3-P:IRF7-P [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
p-4S,T404-IRF3,p-S477,S479-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
Translocation of phosphorylated IRF3,IRF7 dimers into nucleus (Bos taurus)
IRF3-P:IRF7-P [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
TRAF6 mediated IRF7 activation (Bos taurus)
Dimerization of p-IRF7 (Bos taurus)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
Translocation of p-IRF7:p-IRF7 to nucleus (Bos taurus)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
Toll-like Receptor Cascades (Bos taurus)
Toll Like Receptor 3 (TLR3) Cascade (Bos taurus)
TICAM1-dependent activation of IRF3/IRF7 (Bos taurus)
Dimerization of phosphorylated IRF3/IRF7 (Bos taurus)
p-4S,T404-IRF3,p-S477,S479-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
phosphorylated IRF3 and/or IRF7 dimer [cytosol] (Bos taurus)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Bos taurus)
phosphorylated IRF3 and/or IRF7 dimer [cytosol] (Bos taurus)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
Toll Like Receptor 4 (TLR4) Cascade (Bos taurus)
MyD88-independent TLR4 cascade (Bos taurus)
TRIF (TICAM1)-mediated TLR4 signaling (Bos taurus)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Bos taurus)
Dimerization of phosphorylated IRF3/IRF7 (Bos taurus)
p-4S,T404-IRF3,p-S477,S479-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
phosphorylated IRF3 and/or IRF7 dimer [cytosol] (Bos taurus)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Bos taurus)
phosphorylated IRF3 and/or IRF7 dimer [cytosol] (Bos taurus)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Bos taurus)
p-4S,T404-IRF3,p-S477,S479-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling (Bos taurus)
Dimerization of p-IRF7 (Bos taurus)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
Translocation of p-IRF7:p-IRF7 to nucleus (Bos taurus)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
Toll Like Receptor 9 (TLR9) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling (Bos taurus)
Dimerization of p-IRF7 (Bos taurus)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
Translocation of p-IRF7:p-IRF7 to nucleus (Bos taurus)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Bos taurus)
phospho-IRF7 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:A0A3Q1MWF9
Gene Names
IRF7
Reference Genes
ENSEMBL:ENSBTAG00000047680.2
Participates
as an input of
Dimerization of p-IRF7 (Bos taurus)
as a member of
p-4S,T404-IRF3,p-S477,S479-IRF7 [cytosol] (Bos taurus)
as a component of
IRF3-P:IRF7-P [cytosol] (Bos taurus)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Bos taurus)
Other forms of this molecule
phospho-IRF7 [nucleoplasm]
IRF7 [cytosol]
Inferred From
p-S477,S479-IRF7 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 477 (in Homo sapiens)
Coordinate
477
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 479 (in Homo sapiens)
Coordinate
479
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
OpenTargets
ENSG00000185507
VGNC
30278
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