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IL15 [extracellular region]
Stable Identifier
R-BTA-447242
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
extracellular region
Synonyms
IL15, Q28028
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Signaling by Interleukins (Bos taurus)
Interleukin-2 family signaling (Bos taurus)
Interleukin-15 signaling (Bos taurus)
IL15 binds IL15RA (Bos taurus)
IL15 [extracellular region] (Bos taurus)
IL15:IL15RA [plasma membrane] (Bos taurus)
IL15 [extracellular region] (Bos taurus)
IL15 binds IL2RB:JAK1 and IL2RG:JAK3 (Bos taurus)
IL15 [extracellular region] (Bos taurus)
IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL15 [extracellular region] (Bos taurus)
IL15:IL15RA binds IL2RB:JAK1 and IL2RG:JAK3 (Bos taurus)
IL15:IL15RA [plasma membrane] (Bos taurus)
IL15 [extracellular region] (Bos taurus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL15:IL15RA [plasma membrane] (Bos taurus)
IL15 [extracellular region] (Bos taurus)
IL15:IL15RA:IL2RB:JAK1:IL2RG:JAK3 translocates from the plasma membrane to the endosome (Bos taurus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL15:IL15RA [plasma membrane] (Bos taurus)
IL15 [extracellular region] (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL15:IL15RA [plasma membrane] (Bos taurus)
IL15 [extracellular region] (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:STAT3,STAT5,(STAT3:STAT5) [plasma membrane] (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL15:IL15RA [plasma membrane] (Bos taurus)
IL15 [extracellular region] (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:STAT3,STAT5,(STAT3:STAT5) [plasma membrane] (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL15:IL15RA [plasma membrane] (Bos taurus)
IL15 [extracellular region] (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-STAT3,p-STAT5,(p-Y-STAT3:p-STAT5) [plasma membrane] (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL15:IL15RA [plasma membrane] (Bos taurus)
IL15 [extracellular region] (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 [plasma membrane] (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1 [plasma membrane] (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL15:IL15RA [plasma membrane] (Bos taurus)
IL15 [extracellular region] (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2:SOS [plasma membrane] (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 [plasma membrane] (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1 [plasma membrane] (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL15:IL15RA [plasma membrane] (Bos taurus)
IL15 [extracellular region] (Bos taurus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Bos taurus)
IL15:IL15RA:IL2RB:p-Y-JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL15:IL15RA [plasma membrane] (Bos taurus)
IL15 [extracellular region] (Bos taurus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL15:IL15RA [plasma membrane] (Bos taurus)
IL15 [extracellular region] (Bos taurus)
p-Y-STAT3 and p-STAT5 dissociates from IL15:IL15RA:IL2RB:p-JAK1:IL2RG:p-JAK3:p-Y-STAT3:p-STAT5 (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL15:IL15RA [plasma membrane] (Bos taurus)
IL15 [extracellular region] (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-STAT3,p-STAT5,(p-Y-STAT3:p-STAT5) [plasma membrane] (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL15:IL15RA [plasma membrane] (Bos taurus)
IL15 [extracellular region] (Bos taurus)
External Reference Information
External Reference
UniProt:Q28028
Gene Names
IL15
Reference Genes
BioGPS Gene:281248 IL15
ENSEMBL:ENSBTAG00000018200
ENSEMBL:ENSBTAG00000018200.5 IL15
KEGG Gene (Bos taurus):281248 IL15
Monarch:281248 IL15
NCBI Gene:281248 IL15
Reference Transcript
RefSeq:XM_015475375.1 IL15
RefSeq:XM_015475373.1 IL15
RefSeq:XM_005217529.3 IL15
RefSeq:XM_015475376.1 IL15
RefSeq:XM_015475374.1 IL15
RefSeq:NM_174090.1 IL15
Other Identifiers
281248
GO:0001779
GO:0001787
GO:0001866
GO:0002376
GO:0005125
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006486
GO:0007155
GO:0016192
GO:0016607
GO:0023052
GO:0030154
GO:0030225
GO:0032740
GO:0032819
GO:0032825
GO:0035723
GO:0036211
GO:0042102
GO:0042119
GO:0043226
GO:0045062
GO:0045580
GO:0048018
GO:0048469
GO:0048535
GO:0048856
GO:0050691
GO:0050731
GO:0050766
GO:0050778
GO:0098542
GO:0098772
GO:0120163
GO:1901135
GO:1904100
Participates
as an input of
IL15 binds IL2RB:JAK1 and IL2RG:JAK3 (Bos taurus)
IL15 binds IL15RA (Bos taurus)
as a component of
IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL15:IL15RA [plasma membrane] (Bos taurus)
Other forms of this molecule
IL15 [endosome]
Inferred From
IL15 [extracellular region]
(Homo sapiens)
Cross References
RefSeq
XP_015330860.1
,
XP_005217586.1
,
XP_015330862.1
,
NP_776515.1
,
XP_015330861.1
,
XP_015330859.1
OpenTargets
ENSG00000164136
Ensembl
ENSBTAT00000024226
,
ENSBTAP00000024226
,
ENSBTAP00000059902
,
ENSBTAT00000084366
,
ENSBTAG00000018200
VGNC
30116
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