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phospho-VAV2 [cytosol]
Stable Identifier
R-BTA-442307
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
p-Y172-VAV2, A0A3Q1MQP9
Locations in the PathwayBrowser
Expand all
Developmental Biology (Bos taurus)
Nervous system development (Bos taurus)
Axon guidance (Bos taurus)
EPH-Ephrin signaling (Bos taurus)
EPH-ephrin mediated repulsion of cells (Bos taurus)
SFKs phosphorylate VAV2,3 (Bos taurus)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Bos taurus)
p-Y172-VAV2,p-Y173-VAV3 [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
VAV exchanges GTP for GDP on RAC1, activating it (Bos taurus)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Bos taurus)
p-Y172-VAV2,p-Y173-VAV3 [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
L1CAM interactions (Bos taurus)
Signal transduction by L1 (Bos taurus)
Activation of Rac1 by VAV2 (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
Hemostasis (Bos taurus)
Platelet activation, signaling and aggregation (Bos taurus)
GPVI-mediated activation cascade (Bos taurus)
VAV2 is a GEF for Rho/Rac family kinases (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
Immune System (Bos taurus)
Innate Immune System (Bos taurus)
DAP12 interactions (Bos taurus)
DAP12 signaling (Bos taurus)
Activation of RAC1 by VAV2/3 (Bos taurus)
p-5Y-LAT:PLCG1:GADS:p-3Y-SLP-76:BTK:p-VAV [plasma membrane] (Bos taurus)
p-Y172-VAV2,p-Y173-VAV3 [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
p-Y172-VAV2,p-Y173-VAV3 [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
Fc epsilon receptor (FCERI) signaling (Bos taurus)
FCERI mediated MAPK activation (Bos taurus)
Activation of RAC1 by VAV (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
Autophosphorylation of PAK (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
Phosphorylation and activation of VAV (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
Recruitment of PAK to the membrane by binding active RAC1 (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
Fcgamma receptor (FCGR) dependent phagocytosis (Bos taurus)
Regulation of actin dynamics for phagocytic cup formation (Bos taurus)
Activation of RAC1 by VAV (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
Phosphorylation of VAV (Bos taurus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
Src kinases phosphorylate VAV (Bos taurus)
p-VAV family:PIP3 [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
VAV exchanges GTP for GDP on RAC1, activating it (Bos taurus)
p-VAV family:PIP3:RAC1:GDP [plasma membrane] (Bos taurus)
p-VAV family:PIP3 [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Bos taurus)
p-VAV family:PIP3 [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
VEGFR2 mediated vascular permeability (Bos taurus)
PAK1-3 autophosphorylates (Bos taurus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Bos taurus)
p-VAV family:PIP3 [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Bos taurus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Bos taurus)
p-VAV family:PIP3 [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
PAK1-3 dimer disassociates (Bos taurus)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Bos taurus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Bos taurus)
p-VAV family:PIP3 [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Bos taurus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Bos taurus)
p-VAV family:PIP3 [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
RAC1 binds PAK1-3 (Bos taurus)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Bos taurus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Bos taurus)
p-VAV family:PIP3 [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Bos taurus)
p-VAV family:PIP3 [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
p-VAV family:PIP3 binds RAC1:GDP (Bos taurus)
p-VAV family:PIP3 [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
p-VAV family:PIP3:RAC1:GDP [plasma membrane] (Bos taurus)
p-VAV family:PIP3 [plasma membrane] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
phospho-VAV2 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:A0A3Q1MQP9
Gene Names
VAV2
Reference Genes
ENSEMBL:ENSBTAG00000004511.6
ENSEMBL:ENSBTAG00000004511.7 VAV2
Other Identifiers
515718
GO:0005085
GO:0005737
GO:0007165
GO:0016477
GO:0023052
GO:0035556
GO:0046872
GO:0048870
GO:0098772
Participates
as a member of
p-VAV family [cytosol] (Bos taurus)
p-Y172-VAV2,p-Y173-VAV3 [cytosol] (Bos taurus)
p-VAV family [cytosol] (Bos taurus)
Other forms of this molecule
VAV2 [cytosol]
Inferred From
p-Y172-VAV2 [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 172 (in Homo sapiens)
Coordinate
172
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
OpenTargets
ENSG00000160293
Ensembl
ENSBTAT00000086853
,
ENSBTAG00000004511
,
ENSBTAP00000073942
VGNC
36773
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