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SIRT1 [nucleoplasm]
Stable Identifier
R-BTA-427531
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
F1MQB8
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Bos taurus)
Cell junction organization (Bos taurus)
Cell-cell junction organization (Bos taurus)
Adherens junctions interactions (Bos taurus)
Regulation of Homotypic Cell-Cell Adhesion (Bos taurus)
Regulation of Expression and Function of Type I Classical Cadherins (Bos taurus)
Regulation of CDH1 Expression and Function (Bos taurus)
Regulation of CDH1 Gene Transcription (Bos taurus)
Negative Regulation of CDH1 Gene Transcription (Bos taurus)
ZEB1 recruits MPHOSPH8 (MPP8) to CDH1 gene promoter (Bos taurus)
SIRT1 [nucleoplasm] (Bos taurus)
SIRT1:MPHOSPH8:ZEB1:CDH1 gene [nucleoplasm] (Bos taurus)
SIRT1 [nucleoplasm] (Bos taurus)
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to heat stress (Bos taurus)
Regulation of HSF1-mediated heat shock response (Bos taurus)
SIRT1 binds to HSF1 (Bos taurus)
SIRT1 [nucleoplasm] (Bos taurus)
SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] (Bos taurus)
SIRT1 [nucleoplasm] (Bos taurus)
SIRT1 deacetylates HSF1 (Bos taurus)
SIRT1 [nucleoplasm] (Bos taurus)
SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] (Bos taurus)
SIRT1 [nucleoplasm] (Bos taurus)
Developmental Biology (Bos taurus)
MITF-M-regulated melanocyte development (Bos taurus)
Transcriptional and post-translational regulation of MITF-M expression and activity (Bos taurus)
HINT1 binds MITF-M (Bos taurus)
SIRT1 [nucleoplasm] (Bos taurus)
SIRT1 deacetylates HINT1 dimer (Bos taurus)
SIRT1 [nucleoplasm] (Bos taurus)
Gene expression (Transcription) (Bos taurus)
Epigenetic regulation of gene expression (Bos taurus)
Epigenetic regulation by WDR5-containing histone modifying complexes (Bos taurus)
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Bos taurus)
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes (Bos taurus)
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis (Bos taurus)
Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci (Bos taurus)
SIRT1 [nucleoplasm] (Bos taurus)
Negative epigenetic regulation of rRNA expression (Bos taurus)
SIRT1 negatively regulates rRNA expression (Bos taurus)
Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) (Bos taurus)
SIRT1 [nucleoplasm] (Bos taurus)
eNoSC [nucleoplasm] (Bos taurus)
SIRT1 [nucleoplasm] (Bos taurus)
eNoSC deacetylates histone H3 (Bos taurus)
SIRT1 [nucleoplasm] (Bos taurus)
eNoSC [nucleoplasm] (Bos taurus)
SIRT1 [nucleoplasm] (Bos taurus)
eNoSC dimethylates histone H3 at lysine-9 (Bos taurus)
eNoSC [nucleoplasm] (Bos taurus)
SIRT1 [nucleoplasm] (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
FOXO-mediated transcription (Bos taurus)
Regulation of FOXO transcriptional activity by acetylation (Bos taurus)
SIRT1,SIRT3 deacetylate FOXO3 (Bos taurus)
SIRT1,SIRT3 [nucleoplasm] (Bos taurus)
SIRT1 [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:F1MQB8
Reference Genes
ENSEMBL:ENSBTAG00000014023.6
UCSC:F1MQB8
Other Identifiers
613629
Bt.13818.1.S1_at
Bt.20465.1.S1_at
GO:0000012
GO:0000122
GO:0000183
GO:0000720
GO:0000731
GO:0000785
GO:0000791
GO:0000792
GO:0000978
GO:0001525
GO:0001542
GO:0001650
GO:0001678
GO:0001938
GO:0002039
GO:0002821
GO:0003713
GO:0003714
GO:0003824
GO:0004857
GO:0005634
GO:0005635
GO:0005637
GO:0005654
GO:0005677
GO:0005730
GO:0005737
GO:0005739
GO:0005829
GO:0005975
GO:0006094
GO:0006281
GO:0006325
GO:0006355
GO:0006629
GO:0006642
GO:0006974
GO:0006979
GO:0007179
GO:0007283
GO:0007346
GO:0007623
GO:0008047
GO:0008284
GO:0008630
GO:0009267
GO:0010629
GO:0010824
GO:0010868
GO:0010875
GO:0010883
GO:0010906
GO:0016239
GO:0016567
GO:0016605
GO:0016740
GO:0016922
GO:0017136
GO:0019213
GO:0019432
GO:0019899
GO:0019904
GO:0022414
GO:0030154
GO:0030163
GO:0030225
GO:0030512
GO:0030968
GO:0031393
GO:0031507
GO:0031648
GO:0032007
GO:0032041
GO:0032436
GO:0032868
GO:0032922
GO:0032991
GO:0033210
GO:0033553
GO:0033558
GO:0034391
GO:0034979
GO:0035098
GO:0035329
GO:0035331
GO:0035356
GO:0035358
GO:0042127
GO:0042149
GO:0042393
GO:0042542
GO:0042595
GO:0042632
GO:0042771
GO:0042802
GO:0042981
GO:0043065
GO:0043066
GO:0043124
GO:0043161
GO:0043398
GO:0043425
GO:0043518
GO:0043524
GO:0043536
GO:0044321
GO:0045348
GO:0045599
GO:0045722
GO:0045739
GO:0045766
GO:0045786
GO:0045892
GO:0045944
GO:0046015
GO:0046628
GO:0046969
GO:0046970
GO:0050872
GO:0051019
GO:0051152
GO:0051658
GO:0051897
GO:0051898
GO:0055089
GO:0060766
GO:0060907
GO:0061773
GO:0070301
GO:0070403
GO:0070857
GO:0070914
GO:0071356
GO:0071456
GO:0071479
GO:0072331
GO:0072350
GO:0090335
GO:0090400
GO:0097009
GO:0098772
GO:0106231
GO:0140096
GO:0140297
GO:0140416
GO:0140861
GO:0140937
GO:0141050
GO:0141208
GO:0160012
GO:1901797
GO:1902166
GO:1902176
GO:1902237
GO:1904179
GO:1990254
GO:1990830
GO:1990841
GO:2000111
GO:2000655
GO:2000773
GO:2000774
GO:2000781
Participates
as an input of
Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) (Bos taurus)
SIRT1 binds to HSF1 (Bos taurus)
ZEB1 recruits MPHOSPH8 (MPP8) to CDH1 gene promoter (Bos taurus)
as a component of
eNoSC [nucleoplasm] (Bos taurus)
SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] (Bos taurus)
SIRT1:MPHOSPH8:ZEB1:CDH1 gene [nucleoplasm] (Bos taurus)
as an output of
SIRT1 deacetylates HSF1 (Bos taurus)
as a member of
SIRT1,SIRT3 [nucleoplasm] (Bos taurus)
This entity regulates
Positively
Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci
(Bos taurus)
HINT1 binds MITF-M
(Bos taurus)
Inferred From
SIRT1 [nucleoplasm]
(Homo sapiens)
Cross References
ENSEMBL
ENSBTAG00000014023
,
ENSBTAT00000018630
,
ENSBTAP00000018630
VGNC
34630
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