Reactome | GHRH [extracellular region]

GHRH [extracellular region]

Stable Identifier

R-BTA-420068

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

extracellular region

Synonyms

GHRH, P63292

Locations in the PathwayBrowser

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Signal Transduction (Bos taurus)

- Signaling by GPCR (Bos taurus)
  - GPCR downstream signalling (Bos taurus)
    - G alpha (s) signalling events (Bos taurus)
      - Liganded Gs-activating GPCR acts as a GEF for Gs (Bos taurus)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Bos taurus)
        
        GHRH receptor:GHRH [plasma membrane] (Bos taurus)
        
        GHRH [extracellular region] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Bos taurus)
        
        GHRH receptor:GHRH [plasma membrane] (Bos taurus)
        
        GHRH [extracellular region] (Bos taurus)
  - GPCR ligand binding (Bos taurus)
    - Class B/2 (Secretin family receptors) (Bos taurus)
      - Glucagon-type ligand receptors (Bos taurus)
        
        GHRH receptor binds GHRH (Bos taurus)
        
        GHRH [extracellular region] (Bos taurus)
        
        GHRH receptor:GHRH [plasma membrane] (Bos taurus)
        
        GHRH [extracellular region] (Bos taurus)

External Reference Information

External Reference

UniProt:P63292

Gene Names

GHRH

Reference Genes

BioGPS Gene:281191 GHRH

ENSEMBL:ENSBTAG00000012710

ENSEMBL:ENSBTAG00000012710.6 GHRH

KEGG Gene (Bos taurus):281191 GHRH

Monarch:281191 GHRH

NCBI Gene:281191 GHRH

Reference Transcript

RefSeq:NM_178325.1 GHRH

Other Identifiers

281191

GO:0005179

GO:0005184

GO:0005576

GO:0005615

GO:0007189

GO:0008284

GO:0016608

GO:0021984

GO:0023052

GO:0030252

GO:0031770

GO:0032024

GO:0032094

GO:0032880

GO:0035264

GO:0040018

GO:0043195

GO:0043204

GO:0045745

GO:0046879

GO:0046887

GO:0048018

GO:0048856

GO:0051428

GO:0060124

GO:0071277

GO:0098772

GO:1903489

Participates

as an input of

GHRH receptor binds GHRH (Bos taurus)

as a component of

GHRH receptor:GHRH [plasma membrane] (Bos taurus)

Inferred From

GHRH [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_847895.1

OpenTargets

ENSG00000118702

Ensembl

ENSBTAP00000016891, ENSBTAT00000016891, ENSBTAG00000012710

VGNC

29349

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