Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
ACTR1A [cytosol]
Stable Identifier
R-BTA-380258
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
ACTR1A, F2Z4F0
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Prometaphase (Bos taurus)
Recruitment of NuMA to mitotic centrosomes (Bos taurus)
Association of NuMA with microtubules (Bos taurus)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Bos taurus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Bos taurus)
Mature centrosome:nucleated microtubules [cytosol] (Bos taurus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Translocation of NuMA to the centrosomes (Bos taurus)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Bos taurus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Mitotic G2-G2/M phases (Bos taurus)
G2/M Transition (Bos taurus)
AURKA Activation by TPX2 (Bos taurus)
TPX2 binds AURKA at centrosomes (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
TPX2 promotes AURKA autophosphorylation (Bos taurus)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Centrosome:p-T288-AURKA:TPX2:HMMR [cytosol] (Bos taurus)
Centrosome:p-T288-AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Centrosome maturation (Bos taurus)
Loss of proteins required for interphase microtubule organization from the centrosome (Bos taurus)
Loss of C-Nap-1 from centrosomes (Bos taurus)
cNAP-1 depleted centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Loss of Nlp from mitotic centrosomes (Bos taurus)
Dissociation of Phospho-Nlp from the centrosome (Bos taurus)
Nlp-depleted centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
centrosome containing phosphorylated Nlp [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Plk1-mediated phosphorylation of Nlp (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
centrosome containing phosphorylated Nlp [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Recruitment of mitotic centrosome proteins and complexes (Bos taurus)
Recruitment of CDK11p58 to the centrosomes (Bos taurus)
Centrosomes containing recruited CDK11p58 [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Recruitment of Plk1 to centrosomes (Bos taurus)
Centrosome associated Plk1 [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Bos taurus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Regulation of PLK1 Activity at G2/M Transition (Bos taurus)
AJUBA binds centrosome-associated AURKA (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Centrosome:AURKA:AJUBA [cytosol] (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
AJUBA facilitates AURKA autophosphorylation (Bos taurus)
Centrosome:AURKA:AJUBA [cytosol] (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Centrosome:p-T288-AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
AURKA phosphorylates PLK1 (Bos taurus)
Centrosome:p-T288-AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Bos taurus)
Centrosome:p-T288-AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
BORA binds PLK1 and AURKA (Bos taurus)
Centrosome:p-T288-AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Bos taurus)
Centrosome:p-T288-AURKA [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Bos taurus)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Dynactin [cytosol] (Bos taurus)
Dynactin rod [cytosol] (Bos taurus)
Arp1 octameric polymer [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
MHC class II antigen presentation (Bos taurus)
Transport of antigen loaded MHC II molecules to surface (Bos taurus)
ARP-1 [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Dynactin [cytosol] (Bos taurus)
Dynactin rod [cytosol] (Bos taurus)
Arp1 octameric polymer [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Kinesins:Dynactin:microtubule [cytosol] (Bos taurus)
Dynactin [cytosol] (Bos taurus)
Dynactin rod [cytosol] (Bos taurus)
Arp1 octameric polymer [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Asparagine N-linked glycosylation (Bos taurus)
Transport to the Golgi and subsequent modification (Bos taurus)
ER to Golgi Anterograde Transport (Bos taurus)
COPI-mediated anterograde transport (Bos taurus)
ERGIC-to-Golgi vesicles bind dynein:dynactin (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Dynactin [cytosol] (Bos taurus)
Dynactin rod [cytosol] (Bos taurus)
Arp1 octameric polymer [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Dynactin [cytosol] (Bos taurus)
Dynactin rod [cytosol] (Bos taurus)
Arp1 octameric polymer [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Dynactin [cytosol] (Bos taurus)
Dynactin rod [cytosol] (Bos taurus)
Arp1 octameric polymer [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Dynactin [cytosol] (Bos taurus)
Dynactin rod [cytosol] (Bos taurus)
Arp1 octameric polymer [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Organelle biogenesis and maintenance (Bos taurus)
Cilium Assembly (Bos taurus)
Anchoring of the basal body to the plasma membrane (Bos taurus)
C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Bos taurus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
mother centriole:C2CD3 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
mother centriole:C2CD3 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
C2CD3 binds the mother centriole (Bos taurus)
mother centriole [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
mother centriole:C2CD3 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Bos taurus)
basal body:transition zone proteins [cytosol] (Bos taurus)
basal body [cytosol] (Bos taurus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Bos taurus)
basal body:transition zone proteins [cytosol] (Bos taurus)
basal body [cytosol] (Bos taurus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
CP110 and CEP97 dissociate from the centriole (Bos taurus)
basal body [cytosol] (Bos taurus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Bos taurus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Bos taurus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
mother centriole:C2CD3 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
MARK4 binds ODF2 in the centriole (Bos taurus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Bos taurus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
mother centriole:C2CD3 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Bos taurus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Bos taurus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
mother centriole:C2CD3 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Bos taurus)
basal body:transition zone proteins [cytosol] (Bos taurus)
basal body [cytosol] (Bos taurus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Recruitment of transition zone proteins (Bos taurus)
basal body [cytosol] (Bos taurus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
basal body:transition zone proteins [cytosol] (Bos taurus)
basal body [cytosol] (Bos taurus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
The distal appendage proteins recruit TTBK2 (Bos taurus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
mother centriole:C2CD3 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Bos taurus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
mother centriole:C2CD3 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Vesicle-mediated transport (Bos taurus)
Membrane Trafficking (Bos taurus)
ER to Golgi Anterograde Transport (Bos taurus)
COPI-mediated anterograde transport (Bos taurus)
ERGIC-to-Golgi vesicles bind dynein:dynactin (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Dynactin [cytosol] (Bos taurus)
Dynactin rod [cytosol] (Bos taurus)
Arp1 octameric polymer [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Dynactin [cytosol] (Bos taurus)
Dynactin rod [cytosol] (Bos taurus)
Arp1 octameric polymer [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Dynactin [cytosol] (Bos taurus)
Dynactin rod [cytosol] (Bos taurus)
Arp1 octameric polymer [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Dynactin [cytosol] (Bos taurus)
Dynactin rod [cytosol] (Bos taurus)
Arp1 octameric polymer [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
Intra-Golgi and retrograde Golgi-to-ER traffic (Bos taurus)
Golgi-to-ER retrograde transport (Bos taurus)
COPI-independent Golgi-to-ER retrograde traffic (Bos taurus)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Dynactin [cytosol] (Bos taurus)
Dynactin rod [cytosol] (Bos taurus)
Arp1 octameric polymer [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Dynactin [cytosol] (Bos taurus)
Dynactin rod [cytosol] (Bos taurus)
Arp1 octameric polymer [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Bos taurus)
Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Dynactin [cytosol] (Bos taurus)
Dynactin rod [cytosol] (Bos taurus)
Arp1 octameric polymer [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Dynactin [cytosol] (Bos taurus)
Dynactin rod [cytosol] (Bos taurus)
Arp1 octameric polymer [cytosol] (Bos taurus)
ACTR1A [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:F2Z4F0
Gene Names
ACTR1A
Reference Genes
BioGPS Gene:514371 ACTR1A
ENSEMBL:ENSBTAG00000021067.6
KEGG Gene (Bos taurus):514371 ACTR1A
Monarch:514371 ACTR1A
NCBI Gene:514371 ACTR1A
Reference Transcript
RefSeq:NM_001193248.2 ACTR1A
Other Identifiers
514371
Participates
as a component of
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
mother centriole [cytosol] (Bos taurus)
Arp1 octameric polymer [cytosol] (Bos taurus)
Nlp-depleted centrosome [cytosol] (Bos taurus)
centrosome containing phosphorylated Nlp [cytosol] (Bos taurus)
cNAP-1 depleted centrosome [cytosol] (Bos taurus)
centrosome [cytosol] (Bos taurus)
as a member of
ARP-1 [cytosol] (Bos taurus)
Inferred From
ACTR1A [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001180177.1
OpenTargets
ENSG00000138107
Ensembl
ENSBTAG00000021067
,
ENSBTAT00000028053
,
ENSBTAP00000028053
VGNC
25585
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
