Reactome | EIF3M [cytosol]

EIF3M [cytosol]

Stable Identifier

R-BTA-377448

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

EIF3M, A0A3Q1MNJ2

Locations in the PathwayBrowser

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Metabolism of proteins (Bos taurus)

- Translation (Bos taurus)
  - Eukaryotic Translation Initiation (Bos taurus)
    - Cap-dependent Translation Initiation (Bos taurus)
      - Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Bos taurus)
        
        Translation initiation complex formation (Bos taurus)
        
        Formation of translation initiation complexes containing mRNA that does not circularize (Bos taurus)
        
        43S complex [cytosol] (Bos taurus)
        
        eIF3 subunits complex [cytosol] (Bos taurus)
        
        Homologues of EIF3M [cytosol] (Bos taurus)
        
        EIF3M [cytosol] (Bos taurus)
        
        48S complex [cytosol] (Bos taurus)
        
        43S complex [cytosol] (Bos taurus)
        
        eIF3 subunits complex [cytosol] (Bos taurus)
        
        Homologues of EIF3M [cytosol] (Bos taurus)
        
        EIF3M [cytosol] (Bos taurus)
        
        Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Bos taurus)
        
        43S complex [cytosol] (Bos taurus)
        
        eIF3 subunits complex [cytosol] (Bos taurus)
        
        Homologues of EIF3M [cytosol] (Bos taurus)
        
        EIF3M [cytosol] (Bos taurus)
        
        43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Bos taurus)
        
        43S complex [cytosol] (Bos taurus)
        
        eIF3 subunits complex [cytosol] (Bos taurus)
        
        Homologues of EIF3M [cytosol] (Bos taurus)
        
        EIF3M [cytosol] (Bos taurus)
      - Formation of a pool of free 40S subunits (Bos taurus)
        
        eIF3 and eIF1A bind to the 40S subunit (Bos taurus)
        
        40S:eIF3:eIF1A [cytosol] (Bos taurus)
        
        eIF3 subunits complex [cytosol] (Bos taurus)
        
        Homologues of EIF3M [cytosol] (Bos taurus)
        
        EIF3M [cytosol] (Bos taurus)
        
        eIF3 subunits complex [cytosol] (Bos taurus)
        
        Homologues of EIF3M [cytosol] (Bos taurus)
        
        EIF3M [cytosol] (Bos taurus)
      - Formation of the ternary complex, and subsequently, the 43S complex (Bos taurus)
        
        Formation of the 43S pre-initiation complex (Bos taurus)
        
        40S:eIF3:eIF1A [cytosol] (Bos taurus)
        
        eIF3 subunits complex [cytosol] (Bos taurus)
        
        Homologues of EIF3M [cytosol] (Bos taurus)
        
        EIF3M [cytosol] (Bos taurus)
        
        43S complex [cytosol] (Bos taurus)
        
        eIF3 subunits complex [cytosol] (Bos taurus)
        
        Homologues of EIF3M [cytosol] (Bos taurus)
        
        EIF3M [cytosol] (Bos taurus)
      - Ribosomal scanning and start codon recognition (Bos taurus)
        
        Ribosomal scanning (Bos taurus)
        
        48S complex [cytosol] (Bos taurus)
        
        43S complex [cytosol] (Bos taurus)
        
        eIF3 subunits complex [cytosol] (Bos taurus)
        
        Homologues of EIF3M [cytosol] (Bos taurus)
        
        EIF3M [cytosol] (Bos taurus)
        
        Start codon recognition (Bos taurus)
        
        48S complex [cytosol] (Bos taurus)
        
        43S complex [cytosol] (Bos taurus)
        
        eIF3 subunits complex [cytosol] (Bos taurus)
        
        Homologues of EIF3M [cytosol] (Bos taurus)
        
        EIF3M [cytosol] (Bos taurus)
    - L13a-mediated translational silencing of Ceruloplasmin expression (Bos taurus)
      - Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Bos taurus)
        
        43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Bos taurus)
        
        43S complex [cytosol] (Bos taurus)
        
        eIF3 subunits complex [cytosol] (Bos taurus)
        
        Homologues of EIF3M [cytosol] (Bos taurus)
        
        EIF3M [cytosol] (Bos taurus)
        
        phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (Bos taurus)
        
        43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Bos taurus)
        
        43S complex [cytosol] (Bos taurus)
        
        eIF3 subunits complex [cytosol] (Bos taurus)
        
        Homologues of EIF3M [cytosol] (Bos taurus)
        
        EIF3M [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:A0A3Q1MNJ2

Gene Names

EIF3M

Reference Genes

BioGPS Gene:515543 EIF3M

ENSEMBL:ENSBTAG00000051084.1

KEGG:bta:515543 EIF3M

Monarch:515543 EIF3M

NCBI Gene:515543 EIF3M

UCSC:A0A3Q1MNJ2 EIF3M

Reference Transcript

RefSeq:NM_001035312.2 EIF3M

Participates

as a member of

Homologues of EIF3M [cytosol] (Bos taurus)

Inferred From

EIF3M [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001030389.2