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SEH1L [cytosol]
Stable Identifier
R-BTA-376246
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
SEH1L-1, A7YY75
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle Checkpoints (Bos taurus)
Mitotic Spindle Checkpoint (Bos taurus)
Amplification of signal from the kinetochores (Bos taurus)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Bos taurus)
MAD2 associates with the Mad1 kinetochore complex (Bos taurus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
MAD2 converted to an inhibitory state via interaction with Mad1 (Bos taurus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Mad1 binds kinetochore (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Release of activated MAD2 from kinetochores (Bos taurus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Metaphase and Anaphase (Bos taurus)
Mitotic Anaphase (Bos taurus)
Nuclear Envelope (NE) Reassembly (Bos taurus)
Postmitotic nuclear pore complex (NPC) reformation (Bos taurus)
AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Nup107-160 complex:AHCTF1:Chromatin [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
POM121 and NDC1 bind the Nup93 complex (Bos taurus)
Nup93 complex:NUP188:NDC1:POM121:AHCTF1:Chromatin [nuclear envelope] (Bos taurus)
POM121:Nup107-160 complex:AHCTF1:Chromatin [nuclear envelope] (Bos taurus)
Nup107-160 complex:AHCTF1:Chromatin [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
POM121:Nup107-160 complex:AHCTF1:Chromatin [nuclear envelope] (Bos taurus)
Nup107-160 complex:AHCTF1:Chromatin [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
POM121 binds the Nup107-Nup160 complex (Bos taurus)
Nup107-160 complex:AHCTF1:Chromatin [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
POM121:Nup107-160 complex:AHCTF1:Chromatin [nuclear envelope] (Bos taurus)
Nup107-160 complex:AHCTF1:Chromatin [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Separation of Sister Chromatids (Bos taurus)
ESPL1 (Separase) cleaves centromeric cohesin (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Separation of sister chromatids (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Mitotic Prometaphase (Bos taurus)
EML4 and NUDC in mitotic spindle formation (Bos taurus)
EML4 recruits NUDC to mitotic spindle (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Kinetochore capture of astral microtubules (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Resolution of Sister Chromatid Cohesion (Bos taurus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Kinetochore assembly (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
PP2A-B56 dephosphorylates centromeric cohesin (Bos taurus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Phosphorylation of cohesin by PLK1 at centromeres (Bos taurus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Mitotic Prophase (Bos taurus)
Nuclear Envelope Breakdown (Bos taurus)
Nuclear Pore Complex (NPC) Disassembly (Bos taurus)
CDK1 phosphorylates NUP98 (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Nuclear Pore Complex (p-2S,3T-NUP98) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
NEK6/NEK7 phosphorylates NUP98 (Bos taurus)
Nuclear Pore Complex (p-2S,3T-NUP98) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Partially Disassembled NPC [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to heat stress (Bos taurus)
Regulation of HSF1-mediated heat shock response (Bos taurus)
NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Gene expression (Transcription) (Bos taurus)
Gene Silencing by RNA (Bos taurus)
Transcriptional regulation by small RNAs (Bos taurus)
Importin-8 imports AGO2:miRNA into the nucleus (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Metabolism of RNA (Bos taurus)
Metabolism of non-coding RNA (Bos taurus)
snRNP Assembly (Bos taurus)
snRNP nuclear import and release (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Processing of Capped Intron-Containing Pre-mRNA (Bos taurus)
Transport of Mature Transcript to Cytoplasm (Bos taurus)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Bos taurus)
Transport of the export-competent mRNP complex through the NPC (Bos taurus)
NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
mRNP complex dissociates from cytosolic face of NPC (Bos taurus)
NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Transport of Mature mRNAs Derived from Intronless Transcripts (Bos taurus)
Transport of Mature mRNA Derived from an Intronless Transcript (Bos taurus)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Transport of the SLBP Dependant Mature mRNA (Bos taurus)
Docking of Mature Replication Dependent Histone mRNA with the NPC (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Transport of the SLBP independent Mature mRNA (Bos taurus)
Docking of Mature Histone mRNA complex:TAP at the NPC (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Release of the SLBP independent Histone mRNA from the NPC (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
SUMOylation (Bos taurus)
SUMO E3 ligases SUMOylate target proteins (Bos taurus)
SUMOylation of DNA damage response and repair proteins (Bos taurus)
RANBP2 SUMOylates PML with SUMO1 (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
RANBP2 SUMOylates PML with SUMO2 (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
SUMOylation of RNA binding proteins (Bos taurus)
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
SUMOylation of SUMOylation proteins (Bos taurus)
RANBP2 SUMOylates RANBP2 with SUMO1 (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
RANBP2 SUMOylates RANBP2 with SUMO2 (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
SUMOylation of chromatin organization proteins (Bos taurus)
RANBP2 SUMOylates HDAC4 with SUMO1 (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
RANBP2 SUMOylates HDAC4 with SUMO2,3 (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
SUMOylation of ubiquitinylation proteins (Bos taurus)
RANBP2 SUMOylates MDM2 with SUMO1 (Bos taurus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases Activate Formins (Bos taurus)
AURKB phosphorylates DIAPH2-2 at kinetochores (Bos taurus)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
CDC42:GTP recruits DIAPH2-2 to kinetochores (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Nup107-160 complex [cytosol] (Bos taurus)
SEH1L [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:A7YY75
Gene Names
SEH1L
Reference Genes
BioGPS Gene:506509 SEH1L
ENSEMBL:ENSBTAG00000010792
ENSEMBL:ENSBTAG00000010792.6 SEH1L
KEGG Gene (Bos taurus):506509 SEH1L
Monarch:506509 SEH1L
NCBI Gene:506509 SEH1L
Reference Transcript
RefSeq:NM_001103089.2 SEH1L
Other Identifiers
506509
GO:0005198
GO:0005515
Participates
as a component of
Nup107-160 complex [cytosol] (Bos taurus)
Other forms of this molecule
SEH1L [lysosomal membrane]
SEH1L [nuclear envelope]
Inferred From
SEH1L-1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001096559.1
OpenTargets
ENSG00000085415
Ensembl
ENSBTAG00000010792
,
ENSBTAT00000049050
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