Reactome | NPBWR2 [plasma membrane]

NPBWR2 [plasma membrane]

Stable Identifier

R-BTA-374797

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

plasma membrane

Synonyms

NPBWR2, Q8MJV2

Locations in the PathwayBrowser

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Signal Transduction (Bos taurus)

- Signaling by GPCR (Bos taurus)
  - GPCR downstream signalling (Bos taurus)
    - G alpha (i) signalling events (Bos taurus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Neuropeptides B/W receptor:neuropeptides B/W [plasma membrane] (Bos taurus)
        
        Neuropeptides B/W receptors [plasma membrane] (Bos taurus)
        
        NPBWR2 [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Neuropeptides B/W receptor:neuropeptides B/W [plasma membrane] (Bos taurus)
        
        Neuropeptides B/W receptors [plasma membrane] (Bos taurus)
        
        NPBWR2 [plasma membrane] (Bos taurus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Neuropeptides B/W receptor:neuropeptides B/W [plasma membrane] (Bos taurus)
        
        Neuropeptides B/W receptors [plasma membrane] (Bos taurus)
        
        NPBWR2 [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Neuropeptides B/W receptor:neuropeptides B/W [plasma membrane] (Bos taurus)
        
        Neuropeptides B/W receptors [plasma membrane] (Bos taurus)
        
        NPBWR2 [plasma membrane] (Bos taurus)
      - The Ligand:GPCR:Gi complex dissociates (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Neuropeptides B/W receptor:neuropeptides B/W [plasma membrane] (Bos taurus)
        
        Neuropeptides B/W receptors [plasma membrane] (Bos taurus)
        
        NPBWR2 [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Neuropeptides B/W receptor:neuropeptides B/W [plasma membrane] (Bos taurus)
        
        Neuropeptides B/W receptors [plasma membrane] (Bos taurus)
        
        NPBWR2 [plasma membrane] (Bos taurus)
  - GPCR ligand binding (Bos taurus)
    - Class A/1 (Rhodopsin-like receptors) (Bos taurus)
      - Peptide ligand-binding receptors (Bos taurus)
        
        GPCR neuropeptide receptor binds neuropeptides B and W (Bos taurus)
        
        Neuropeptides B/W receptor:neuropeptides B/W [plasma membrane] (Bos taurus)
        
        Neuropeptides B/W receptors [plasma membrane] (Bos taurus)
        
        NPBWR2 [plasma membrane] (Bos taurus)
        
        Neuropeptides B/W receptors [plasma membrane] (Bos taurus)
        
        NPBWR2 [plasma membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:Q8MJV2

Gene Names

NPBWR2

Reference Genes

BioGPS Gene:281208 NPBWR2

ENSEMBL:ENSBTAG00000047704

ENSEMBL:ENSBTAG00000047704.2 NPBWR2

KEGG Gene (Bos taurus):281208 NPBWR2

Monarch:281208 NPBWR2

NCBI Gene:281208 NPBWR2

Reference Transcript

RefSeq:NM_174075.1 NPBWR2

Other Identifiers

281208

GO:0004930

GO:0007186

GO:0008188

GO:0016020

GO:0023052

GO:0060089

Participates

as a member of

Neuropeptides B/W receptors [plasma membrane] (Bos taurus)

Inferred From

NPBWR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_776500.1

OpenTargets

ENSG00000125522

Ensembl

ENSBTAT00000065755, ENSBTAG00000047704, ENSBTAP00000054391

VGNC

106846