Reactome | SST [extracellular region]

SST [extracellular region]

Stable Identifier

R-BTA-374738

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

extracellular region

Synonyms

SST(103-116), F1N145

Locations in the PathwayBrowser

Expand all

Signal Transduction (Bos taurus)

- Signaling by GPCR (Bos taurus)
  - GPCR downstream signalling (Bos taurus)
    - G alpha (i) signalling events (Bos taurus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Bos taurus)
        
        Somatostatin, cortistatin [extracellular region] (Bos taurus)
        
        SST [extracellular region] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Bos taurus)
        
        Somatostatin, cortistatin [extracellular region] (Bos taurus)
        
        SST [extracellular region] (Bos taurus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Bos taurus)
        
        Somatostatin, cortistatin [extracellular region] (Bos taurus)
        
        SST [extracellular region] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Bos taurus)
        
        Somatostatin, cortistatin [extracellular region] (Bos taurus)
        
        SST [extracellular region] (Bos taurus)
      - The Ligand:GPCR:Gi complex dissociates (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Bos taurus)
        
        Somatostatin, cortistatin [extracellular region] (Bos taurus)
        
        SST [extracellular region] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Bos taurus)
        
        Somatostatin, cortistatin [extracellular region] (Bos taurus)
        
        SST [extracellular region] (Bos taurus)
  - GPCR ligand binding (Bos taurus)
    - Class A/1 (Rhodopsin-like receptors) (Bos taurus)
      - Peptide ligand-binding receptors (Bos taurus)
        
        Somatostatin receptors bind somatostatin and cortistatin (Bos taurus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Bos taurus)
        
        Somatostatin, cortistatin [extracellular region] (Bos taurus)
        
        SST [extracellular region] (Bos taurus)
        
        Somatostatin, cortistatin [extracellular region] (Bos taurus)
        
        SST [extracellular region] (Bos taurus)

External Reference Information

External Reference

UniProt:F1N145

Gene Names

SST

Reference Genes

ENSEMBL:ENSBTAG00000017312.4

Other Identifiers

280932

GO:0005179

GO:0005576

GO:0005615

GO:0023052

GO:0030334

GO:0038170

GO:0048018

GO:0048870

GO:0098772

GO:0098982

GO:0099072

Participates

as a member of

Somatostatin, cortistatin [extracellular region] (Bos taurus)

Other forms of this molecule

SST [extracellular region]

Inferred From

Somatostatin [extracellular region] (Homo sapiens)

SST(103-116) [extracellular region] (Homo sapiens)

Cross References

OpenTargets

ENSG00000157005

Ensembl

ENSBTAG00000017312, ENSBTAP00000023020, ENSBTAT00000023020

VGNC

35324