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TNKS [cytosol]
Stable Identifier
R-BTA-3640825
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
TNKS, E1B8R5
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Deubiquitination (Bos taurus)
Ub-specific processing proteases (Bos taurus)
USP34 deubiquitinates AXIN1,AXIN2 (Bos taurus)
RibC-AXIN:TNKS:RNF146 [cytosol] (Bos taurus)
RibC-AXIN:TNKS [cytosol] (Bos taurus)
TNKS1/2 [cytosol] (Bos taurus)
TNKS [cytosol] (Bos taurus)
Ub-RibC-AXIN:TNKS:RNF146 [cytosol] (Bos taurus)
TNKS1/2 [cytosol] (Bos taurus)
TNKS [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Intracellular signaling by second messengers (Bos taurus)
PIP3 activates AKT signaling (Bos taurus)
PTEN Regulation (Bos taurus)
Regulation of PTEN stability and activity (Bos taurus)
TNKS and TNKS2 PARylate PTEN (Bos taurus)
TNKS1/2 [cytosol] (Bos taurus)
TNKS [cytosol] (Bos taurus)
Signaling by WNT (Bos taurus)
TCF dependent signaling in response to WNT (Bos taurus)
Degradation of AXIN (Bos taurus)
RNF146 binds RibC-AXIN:TNKS complex (Bos taurus)
RibC-AXIN:TNKS [cytosol] (Bos taurus)
TNKS1/2 [cytosol] (Bos taurus)
TNKS [cytosol] (Bos taurus)
RibC-AXIN:TNKS:RNF146 [cytosol] (Bos taurus)
RibC-AXIN:TNKS [cytosol] (Bos taurus)
TNKS1/2 [cytosol] (Bos taurus)
TNKS [cytosol] (Bos taurus)
RNF146 ubiquitinates ADP-ribosylated AXIN (Bos taurus)
RibC-AXIN:TNKS:RNF146 [cytosol] (Bos taurus)
RibC-AXIN:TNKS [cytosol] (Bos taurus)
TNKS1/2 [cytosol] (Bos taurus)
TNKS [cytosol] (Bos taurus)
Ub-RibC-AXIN:TNKS:RNF146 [cytosol] (Bos taurus)
TNKS1/2 [cytosol] (Bos taurus)
TNKS [cytosol] (Bos taurus)
Tankyrase ADP-ribosylates AXIN (Bos taurus)
AXIN:TNKS [cytosol] (Bos taurus)
TNKS1/2 [cytosol] (Bos taurus)
TNKS [cytosol] (Bos taurus)
RibC-AXIN:TNKS [cytosol] (Bos taurus)
TNKS1/2 [cytosol] (Bos taurus)
TNKS [cytosol] (Bos taurus)
TNKS1/2 [cytosol] (Bos taurus)
TNKS [cytosol] (Bos taurus)
Tankyrase binds AXIN (Bos taurus)
AXIN:TNKS [cytosol] (Bos taurus)
TNKS1/2 [cytosol] (Bos taurus)
TNKS [cytosol] (Bos taurus)
TNKS1/2 [cytosol] (Bos taurus)
TNKS [cytosol] (Bos taurus)
Ub-RibC-AXIN is degraded by the proteasome (Bos taurus)
TNKS1/2 [cytosol] (Bos taurus)
TNKS [cytosol] (Bos taurus)
Ub-RibC-AXIN:TNKS:RNF146 [cytosol] (Bos taurus)
TNKS1/2 [cytosol] (Bos taurus)
TNKS [cytosol] (Bos taurus)
USP34 deubiquitinates AXIN1,AXIN2 (Bos taurus)
RibC-AXIN:TNKS:RNF146 [cytosol] (Bos taurus)
RibC-AXIN:TNKS [cytosol] (Bos taurus)
TNKS1/2 [cytosol] (Bos taurus)
TNKS [cytosol] (Bos taurus)
Ub-RibC-AXIN:TNKS:RNF146 [cytosol] (Bos taurus)
TNKS1/2 [cytosol] (Bos taurus)
TNKS [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:E1B8R5
Gene Names
TNKS
Reference Genes
BioGPS Gene:535030 TNKS
ENSEMBL:ENSBTAG00000001463.5
ENSEMBL:ENSBTAG00000001463.6 TNKS
KEGG Gene (Bos taurus):535030 TNKS
Monarch:535030 TNKS
NCBI Gene:535030 TNKS
Reference Transcript
RefSeq:NM_001206160.1 TNKS
RefSeq:XM_015460863.1 TNKS
Other Identifiers
535030
GO:0000209
GO:0000278
GO:0000781
GO:0003824
GO:0003950
GO:0005634
GO:0005635
GO:0005654
GO:0005694
GO:0005794
GO:0005829
GO:0005856
GO:0006351
GO:0006355
GO:0007059
GO:0008270
GO:0016604
GO:0016740
GO:0023052
GO:0031965
GO:0032200
GO:0032212
GO:0036211
GO:0042393
GO:0043226
GO:0045944
GO:0070198
GO:0070213
GO:0090263
GO:0097431
GO:0140014
GO:0140096
GO:1904355
GO:1904357
GO:1904908
GO:1990404
Participates
as a member of
TNKS1/2 [cytosol] (Bos taurus)
Inferred From
TNKS [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001193089.1
,
XP_015316349.1
OpenTargets
ENSG00000173273
Ensembl
ENSBTAG00000001463
,
ENSBTAT00000001917
,
ENSBTAP00000001917
VGNC
36184
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