Gnat1-GDP binds to Gnb1:Gngt1

Stable Identifier
R-BTA-3229197
Type
Reaction [binding]
Species
Bos taurus
Compartment
photoreceptor disc membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Gnat1-GDP binds to Gnb1:Gngt1
Once transducin alpha subunit (Gnat1) is deactivated by hydrolysis of bound GTP to GDP, it reassociates with transducin beta:gamma subunits (Gnb1:Gngt1) to form inactive transducin (Gt-GDP). A stoichiometric overabundance of Gnb1:Gngt1 facilitates the reassociation event (Clark et al. 2006, Fung et al. 1981).
Literature References
PubMed ID Title Journal Year
6264430 Flow of information in the light-triggered cyclic nucleotide cascade of vision

Fung, BK, Hurley, JB, Stryer, L

Proc. Natl. Acad. Sci. U.S.A. 1981
16895762 Transducin subunit stoichiometry and cellular distribution in rod outer segments

Springmeyer, ML, Clark, CR, Clack, JW, Witzmann, FA

Cell Biol. Int. 2006
Participants
Input
Output
Orthologous Events
GNAT1-GDP binds to GNB1:GNGT1 (Homo sapiens)
Authored
Jassal, B  (2013-03-26)
Reviewed
Makino, C  (2013-04-11)
Created
Jassal, B  (2013-03-26)
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