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CXCL12 [extracellular region]
Stable Identifier
R-BTA-2980693
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
extracellular region
Synonyms
CXCL12(22-93), A0A3Q1M085
Locations in the PathwayBrowser
Expand all
Developmental Biology (Bos taurus)
Nervous system development (Bos taurus)
Axon guidance (Bos taurus)
Signaling by ROBO receptors (Bos taurus)
SLIT2:ROBO1 binds CXCR4 (Bos taurus)
CXCL12:CXCR4:ROBO1:SLIT2 [plasma membrane] (Bos taurus)
CXCR4:CXCL12 [plasma membrane] (Bos taurus)
CXCL12 [extracellular region] (Bos taurus)
CXCR4:CXCL12 [plasma membrane] (Bos taurus)
CXCL12 [extracellular region] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (i) signalling events (Bos taurus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
CXCR4,7:CXCL12 [plasma membrane] (Bos taurus)
CXCL12 [extracellular region] (Bos taurus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
CXCR4,7:CXCL12 [plasma membrane] (Bos taurus)
CXCL12 [extracellular region] (Bos taurus)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
CXCR4,7:CXCL12 [plasma membrane] (Bos taurus)
CXCL12 [extracellular region] (Bos taurus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
CXCR4,7:CXCL12 [plasma membrane] (Bos taurus)
CXCL12 [extracellular region] (Bos taurus)
The Ligand:GPCR:Gi complex dissociates (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
CXCR4,7:CXCL12 [plasma membrane] (Bos taurus)
CXCL12 [extracellular region] (Bos taurus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
CXCR4,7:CXCL12 [plasma membrane] (Bos taurus)
CXCL12 [extracellular region] (Bos taurus)
GPCR ligand binding (Bos taurus)
Class A/1 (Rhodopsin-like receptors) (Bos taurus)
Peptide ligand-binding receptors (Bos taurus)
Chemokine receptors bind chemokines (Bos taurus)
Receptors CXCR4 and 7 bind CXCL12 ligand (Bos taurus)
CXCL12 [extracellular region] (Bos taurus)
CXCR4,7:CXCL12 [plasma membrane] (Bos taurus)
CXCL12 [extracellular region] (Bos taurus)
External Reference Information
External Reference
UniProt:A0A3Q1M085
Gene Names
CXCL12
Reference Genes
BioGPS Gene:613811 CXCL12
ENSEMBL:ENSBTAG00000005077.5
ENSEMBL:ENSBTAG00000005077.6 CXCL12
Monarch:613811 CXCL12
NCBI Gene:613811 CXCL12
Reference Transcript
RefSeq:XM_005226615.3 CXCL12
Other Identifiers
613811
GO:0002376
GO:0005178
GO:0007155
GO:0008009
GO:0012501
GO:0023052
GO:0033622
GO:0038146
GO:0038160
GO:0042379
GO:0045236
GO:0045785
GO:0048018
GO:0048856
GO:0048870
GO:0060326
GO:0065003
GO:0070098
GO:0090026
GO:0098772
GO:1902230
GO:1903237
GO:1904018
GO:1990869
GO:2000406
GO:2000669
Participates
as a component of
CXCR4:CXCL12 [plasma membrane] (Bos taurus)
CXCR4,7:CXCL12 [plasma membrane] (Bos taurus)
as an input of
Receptors CXCR4 and 7 bind CXCL12 ligand (Bos taurus)
Inferred From
CXCL12(22-93) [extracellular region]
(Homo sapiens)
Cross References
RefSeq
XP_005226672.1
OpenTargets
ENSG00000107562
Ensembl
ENSBTAT00000077980
,
ENSBTAG00000005077
,
ENSBTAP00000066613
VGNC
27848
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