BGN binds Collagen types II, III, IV

Stable Identifier
Reaction [binding]
Bos taurus
SVG |   | PPTX  | SBGN
BGN binds Collagen types II, III, IV

Biglycan is a member of the small leucine-rich repeat proteoglycan (SLRP) family, which also includes decorin, fibromodulin (Hedlund et al. 1994 - binding to collagen II), lumican and asporin (Hedbom & Heinegard 1993, Ezura et al. 2000). All appear to be involved in collagen fibril formation and matrix assembly (Ameye & Young 2002). Biglycan binds collagen types I (Schönherr et al. 1995), II (Bovine, using pig byglycan - Vynios et al. 2001, Bovine, using bovine biglycan - Douglas et al. 2008), III (Bovine, using bovine biglycan - Douglas et al. 2008), VI (Wiberg et al. 2001) and IX (Chen et al. 2006 - species source of collagen/biglycan unknown).

Literature References
PubMed ID Title Journal Year
19542224 The first draft of the endostatin interaction network

Faye, C, Chautard, E, Olsen, BR, Ricard-Blum, S

J. Biol. Chem. 2009
17635036 Influence of collagen-fibril-based coatings containing decorin and biglycan on osteoblast behavior

Douglas, T, Hempel, U, Mietrach, C, Viola, M, Vigetti, D, Heinemann, S, Bierbaum, S, Scharnweber, D, Worch, H

J Biomed Mater Res A 2008
11698112 The interactions of cartilage proteoglycans with collagens are determined by their structures

Vynios, DH, Papageorgakopoulou, N, Sazakli, H, Tsiganos, CP

Biochimie 2001
Orthologous Events
Cite Us!