Reactome | PKLR [cytosol]

PKLR [cytosol]

Stable Identifier

R-BTA-211388

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

PKLR-2, Q1JPG7

Locations in the PathwayBrowser

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Metabolism (Bos taurus)

- Aerobic respiration and respiratory electron transport (Bos taurus)
  - Pyruvate metabolism (Bos taurus)
    - PKM dephosphorylates PEP to PYR (Bos taurus)
      - pyruvate kinase tetramer [cytosol] (Bos taurus)
        
        pyruvate kinase complex, liver and RBC [cytosol] (Bos taurus)
        
        PKLR [cytosol] (Bos taurus)
- Metabolism of carbohydrates (Bos taurus)
  - Glucose metabolism (Bos taurus)
    - Glycolysis (Bos taurus)
      - PKM dephosphorylates PEP to PYR (Bos taurus)
        
        pyruvate kinase tetramer [cytosol] (Bos taurus)
        
        pyruvate kinase complex, liver and RBC [cytosol] (Bos taurus)
        
        PKLR [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:Q1JPG7

Gene Names

PKLR

Reference Genes

BioGPS Gene:539579 PKLR

ENSEMBL:ENSBTAG00000017056.6

KEGG Gene (Bos taurus):539579 PKLR

Monarch:539579 PKLR

NCBI Gene:539579 PKLR

Reference Transcript

RefSeq:NM_001076176.1 PKLR

Other Identifiers

539579

GO:0000166

GO:0000287

GO:0003824

GO:0004743

GO:0005524

GO:0005737

GO:0005975

GO:0006091

GO:0006096

GO:0008152

GO:0016301

GO:0016310

GO:0016740

GO:0030955

GO:0032869

GO:0046872

GO:0055086

GO:1901135

Participates

as a component of

pyruvate kinase complex, liver and RBC [cytosol] (Bos taurus)

Inferred From

Pyruvate kinase, R/L type [cytosol] (Homo sapiens)

PKLR-2 [cytosol] (Homo sapiens)

PKLR-1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001069644.1

OpenTargets

ENSG00000143627

Ensembl

ENSBTAG00000017056, ENSBTAT00000046947, ENSBTAT00000086042, ENSBTAP00000061000, ENSBTAP00000044193

VGNC

32943

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