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VCAN [Golgi lumen]
Stable Identifier
R-BTA-2064010
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
Golgi lumen
Synonyms
Gal-Gal-Xyl-VCAN, P81282
Locations in the PathwayBrowser
Expand all
Metabolism (Bos taurus)
Metabolism of carbohydrates (Bos taurus)
Glycosaminoglycan metabolism (Bos taurus)
Chondroitin sulfate/dermatan sulfate metabolism (Bos taurus)
A tetrasaccharide linker sequence is required for GAG synthesis (Bos taurus)
B3GALT6 transfers Gal to the tetrasaccharide linker (Bos taurus)
Gal-Gal-Xyl-proteins [Golgi lumen] (Bos taurus)
VCAN [Golgi lumen] (Bos taurus)
B3GAT dimers transfer GlcA to tetrasaccharide linker (Bos taurus)
Gal-Gal-Xyl-proteins [Golgi lumen] (Bos taurus)
VCAN [Golgi lumen] (Bos taurus)
B3GAT3 dimer transfers GlcA to tetrasaccharide linker (Bos taurus)
Gal-Gal-Xyl-proteins [Golgi lumen] (Bos taurus)
VCAN [Golgi lumen] (Bos taurus)
Heparan sulfate/heparin (HS-GAG) metabolism (Bos taurus)
A tetrasaccharide linker sequence is required for GAG synthesis (Bos taurus)
B3GALT6 transfers Gal to the tetrasaccharide linker (Bos taurus)
Gal-Gal-Xyl-proteins [Golgi lumen] (Bos taurus)
VCAN [Golgi lumen] (Bos taurus)
B3GAT dimers transfer GlcA to tetrasaccharide linker (Bos taurus)
Gal-Gal-Xyl-proteins [Golgi lumen] (Bos taurus)
VCAN [Golgi lumen] (Bos taurus)
B3GAT3 dimer transfers GlcA to tetrasaccharide linker (Bos taurus)
Gal-Gal-Xyl-proteins [Golgi lumen] (Bos taurus)
VCAN [Golgi lumen] (Bos taurus)
External Reference Information
External Reference
UniProt:P81282
Gene Names
VCAN
Reference Genes
BioGPS Gene:282662 VCAN
ENSEMBL:ENSBTAG00000014906
ENSEMBL:ENSBTAG00000014906.7 VCAN
KEGG Gene (Bos taurus):282662 VCAN
Monarch:282662 VCAN
NCBI Gene:282662 VCAN
Reference Transcript
RefSeq:XM_015472358.1 VCAN
RefSeq:NM_181035.2 VCAN
Other Identifiers
282662
GO:0001501
GO:0001750
GO:0002052
GO:0005509
GO:0005540
GO:0005576
GO:0005615
GO:0005929
GO:0007155
GO:0007417
GO:0010001
GO:0030154
GO:0030246
GO:0030312
GO:0031012
GO:0033165
GO:0042995
GO:0043226
GO:0045202
GO:0048856
GO:0072534
Participates
as a member of
Gal-Gal-Xyl-proteins [Golgi lumen] (Bos taurus)
Other forms of this molecule
VCAN [Golgi lumen]
VCAN [Golgi lumen]
VCAN [Golgi lumen]
VCAN [Golgi lumen]
VCAN [lysosomal lumen]
VCAN [lysosomal lumen]
VCAN [lysosomal lumen]
VCAN [lysosomal lumen]
VCAN [lysosomal lumen]
VCAN [extracellular region]
VCAN [extracellular region]
VCAN [endoplasmic reticulum lumen]
phospho-VCAN [endoplasmic reticulum lumen]
VCAN [Golgi lumen]
VCAN [Golgi lumen]
VCAN [Golgi lumen]
VCAN [Golgi lumen]
VCAN [Golgi lumen]
VCAN [Golgi lumen]
VCAN [Golgi lumen]
VCAN [Golgi lumen]
VCAN [Golgi lumen]
VCAN [Golgi lumen]
VCAN [extracellular region]
VCAN [extracellular region]
VCAN [extracellular region]
VCAN [lysosomal lumen]
VCAN [lysosomal lumen]
VCAN [extracellular region]
Inferred From
Gal-Gal-Xyl-VCAN [Golgi lumen]
(Homo sapiens)
Modified Residues
Name
O-xylosyl-L-serine (ChEBI:63503) at unknown position
Modification
beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group
PsiMod Name
O-xylosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-xylosylserine.
Cross References
RefSeq
NP_851378.1
,
XP_015327844.1
OpenTargets
ENSG00000038427
Ensembl
ENSBTAT00000042717
,
ENSBTAG00000014906
,
ENSBTAP00000040348
VGNC
36778
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