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YWHAB dimer [cytosol]
Stable Identifier
R-BTA-2028645
Type
Complex
Species
Bos taurus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle Checkpoints (Bos taurus)
G2/M Checkpoints (Bos taurus)
G2/M DNA damage checkpoint (Bos taurus)
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Bos taurus)
Association of p-S216-CDC25C with 14-3-3 proteins (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
FOXO-mediated transcription (Bos taurus)
Regulation of localization of FOXO transcription factors (Bos taurus)
14-3-3 proteins bind AKT-phosphorylated FOXO1 (Bos taurus)
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p-T24,S256,S319-FOXO1:YWHAZ,YWHAQ,YWHAG,YWHAB [cytosol] (Bos taurus)
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
TP53 Regulates Metabolic Genes (Bos taurus)
DDIT4 binds 14-3-3 dimer (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
DDIT4:14-3-3 dimer [cytosol] (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
DDIT4:14-3-3 dimer [cytosol] (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p-S939,T1462-TSC2:14-3-3 dimer [cytosol] (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
Programmed Cell Death (Bos taurus)
Apoptosis (Bos taurus)
Intrinsic Pathway for Apoptosis (Bos taurus)
Activation of BH3-only proteins (Bos taurus)
Activation of BAD and translocation to mitochondria (Bos taurus)
Activation of BAD by calcineurin (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
14-3-3 proteins:p-S99-BAD complex [cytosol] (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
Sequestration of BAD protein by 14-3-3 (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
14-3-3 proteins:p-S99-BAD complex [cytosol] (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
MAP2K and MAPK activation (Bos taurus)
Dissociation of RAS:RAF complex (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
Dual mechanism MAPK inhibitors bind MAPKs (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
MAP2Ks and MAPKs bind to the activated RAF complex (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
MAP2Ks phosphorylate MAPKs (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
RAF phosphorylates MAP2K dimer (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
Negative regulation of MAPK pathway (Bos taurus)
PEBP1 binds activated RAF1 (Bos taurus)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
PP2A dephosphorylates RAF1 (Bos taurus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
PP5 dephosphorylates RAF1 S338 (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
RAF activation (Bos taurus)
"Activator" RAF:YWHAB dimer binds RAS:GTP (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
Inactive RAFs bind YWHAB (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
inactive RAFs:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs (Bos taurus)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
inactive RAFs:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
PP2A dephosphorylates KSR1 (Bos taurus)
p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
PP2A dephosphorylates inactive RAFs (Bos taurus)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
inactive RAFs:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
Phosphorylation of RAF (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
Raf dimer inhibitors bind RAF heterodimers (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer dissociates from KSR1:MARK3 (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer dissociates from dephosphorylated RAF (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
Signaling by Hippo (Bos taurus)
YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p-YAP1:YWHAB [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases activate PKNs (Bos taurus)
Association of p-S216-CDC25C with 14-3-3 proteins (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
YWHAB dimer [cytosol] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
YWHAB [cytosol]
(Bos taurus)
Participates
as a member of
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Bos taurus)
14-3-3 dimer [cytosol] (Bos taurus)
as an input of
YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 (Bos taurus)
Inactive RAFs bind YWHAB (Bos taurus)
p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Bos taurus)
as a component of
p-YAP1:YWHAB [cytosol] (Bos taurus)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Bos taurus)
inactive RAFs:YWHAB dimer [cytosol] (Bos taurus)
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Bos taurus)
p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
'activator' RAF:YWHAB dimer [cytosol] (Bos taurus)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
as an output of
YWHAB dimer dissociates from dephosphorylated RAF (Bos taurus)
YWHAB dimer dissociates from KSR1:MARK3 (Bos taurus)
Inferred From
YWHAB dimer [cytosol]
(Homo sapiens)
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