Reactome | BCL10 [cytosol]

BCL10 [cytosol]

Stable Identifier

R-BTA-202447

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

Q17QJ6

Locations in the PathwayBrowser

Expand all

Immune System (Bos taurus)

- Adaptive Immune System (Bos taurus)
  - TCR signaling (Bos taurus)
    - Downstream TCR signaling (Bos taurus)
      - Interaction of Bcl10 to CARMA1 (Bos taurus)
        
        BCL10 [cytosol] (Bos taurus)
        
        Bcl10 bound to CARMA1 [plasma membrane] (Bos taurus)
        
        BCL10 [cytosol] (Bos taurus)
      - Phosphorylation of Bcl10 (Bos taurus)
        
        Bcl10 bound to CARMA1 [plasma membrane] (Bos taurus)
        
        BCL10 [cytosol] (Bos taurus)
- Innate Immune System (Bos taurus)
  - C-type lectin receptors (CLRs) (Bos taurus)
    - CLEC7A (Dectin-1) signaling (Bos taurus)
      - BCL10 binds CARD9 (Bos taurus)
        
        BCL10 [cytosol] (Bos taurus)
        
        p-T231-CARD9 oligomer:BCL10 [plasma membrane] (Bos taurus)
        
        BCL10 [cytosol] (Bos taurus)
      - BCL10 oligomerizes (Bos taurus)
        
        BCL10 [cytosol] (Bos taurus)
        
        p-T231-CARD9 oligomer:BCL10 [plasma membrane] (Bos taurus)
        
        BCL10 [cytosol] (Bos taurus)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Bos taurus)
        
        BCL10 oligomer [cytosol] (Bos taurus)
        
        BCL10 [cytosol] (Bos taurus)
      - TRAF6 oligomerizes (Bos taurus)
        
        p-T231-CARD9:BCL10:MALT1 oligomers:TRAF6 [plasma membrane] (Bos taurus)
        
        p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane] (Bos taurus)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Bos taurus)
        
        BCL10 oligomer [cytosol] (Bos taurus)
        
        BCL10 [cytosol] (Bos taurus)
        
        p-T231-CARD9:BCL10:MALT1:TRAF6 oligomers [plasma membrane] (Bos taurus)
        
        p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane] (Bos taurus)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Bos taurus)
        
        BCL10 oligomer [cytosol] (Bos taurus)
        
        BCL10 [cytosol] (Bos taurus)
  - Fc epsilon receptor (FCERI) signaling (Bos taurus)
    - FCERI mediated NF-kB activation (Bos taurus)
      - Activation of TAK1 complex bound to pUb-TRAF6 (Bos taurus)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Bos taurus)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6 [plasma membrane] (Bos taurus)
        
        CBM oligomer:oligo-K63-poly Ub-TRAF6 oligomer [plasma membrane] (Bos taurus)
        
        BCL10 oligomer [cytosol] (Bos taurus)
        
        BCL10 [cytosol] (Bos taurus)
      - Oligomerization of TRAF6 (Bos taurus)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6 [plasma membrane] (Bos taurus)
        
        CBM oligomer:TRAF6 [plasma membrane] (Bos taurus)
        
        BCL10 oligomer:MALT1 oligomer:TRAF6 [cytosol] (Bos taurus)
        
        BCL10 oligomer [cytosol] (Bos taurus)
        
        BCL10 [cytosol] (Bos taurus)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6 oligomer [plasma membrane] (Bos taurus)
        
        CBM oligomer:TRAF6 oligomer [plasma membrane] (Bos taurus)
        
        BCL10 oligomer [cytosol] (Bos taurus)
        
        BCL10 [cytosol] (Bos taurus)
      - Recruitment of TRAF6 to CBM complex by binding to MALT1 (Bos taurus)
        
        DAG:p-5Y-PKC-theta:CBM oligomer [plasma membrane] (Bos taurus)
        
        CBM oligomer [plasma membrane] (Bos taurus)
        
        BCL10 oligomer [cytosol] (Bos taurus)
        
        BCL10 [cytosol] (Bos taurus)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6 [plasma membrane] (Bos taurus)
        
        CBM oligomer:TRAF6 [plasma membrane] (Bos taurus)
        
        BCL10 oligomer:MALT1 oligomer:TRAF6 [cytosol] (Bos taurus)
        
        BCL10 oligomer [cytosol] (Bos taurus)
        
        BCL10 [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:Q17QJ6

Reference Genes

BioGPS Gene:540824

ENSEMBL:ENSBTAG00000013851

KEGG Gene (Bos taurus):540824

Monarch:540824

NCBI Gene:540824

Reference Transcript

RefSeq:NM_001078028.1

Other Identifiers

540824

Bt.11445.1.A1_at

Bt.19656.1.S1_at

Bt.19656.3.A1_at

GO:0001772

GO:0001783

GO:0001843

GO:0002020

GO:0002096

GO:0002224

GO:0002250

GO:0002376

GO:0002906

GO:0003674

GO:0003713

GO:0005575

GO:0005622

GO:0005634

GO:0005737

GO:0005764

GO:0005773

GO:0005829

GO:0005856

GO:0005881

GO:0005886

GO:0006464

GO:0006915

GO:0006950

GO:0006968

GO:0007155

GO:0007165

GO:0007249

GO:0008022

GO:0008134

GO:0008150

GO:0008219

GO:0009058

GO:0009620

GO:0009790

GO:0016064

GO:0019209

GO:0019899

GO:0019900

GO:0019901

GO:0030234

GO:0031398

GO:0031625

GO:0031663

GO:0032094

GO:0032449

GO:0032757

GO:0032991

GO:0033674

GO:0034641

GO:0042327

GO:0042592

GO:0042802

GO:0042981

GO:0043065

GO:0043123

GO:0043226

GO:0043280

GO:0043422

GO:0043621

GO:0045087

GO:0045121

GO:0045893

GO:0048471

GO:0048646

GO:0048856

GO:0050700

GO:0050852

GO:0050856

GO:0050870

GO:0051059

GO:0051092

GO:0070231

GO:0071222

GO:0071260

GO:2001238

Participant Of

input

hasComponent

repeatedUnit

BCL10 oligomer [cytosol]

Other forms of this molecule

K48polyUb-BCL10 [cytosol]

phospho-p-BCL10 [cytosol]

Inferred From

BCL10 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001071496.1

Ensembl

ENSBTAT00000018398, ENSBTAP00000018398, ENSBTAG00000013851

VGNC

53853

Cite Us!