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ACVR2A [plasma membrane]
Stable Identifier
R-BTA-201659
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
plasma membrane
Synonyms
Q28043
Locations in the PathwayBrowser
Expand all
Signal Transduction (Bos taurus)
Signaling by TGFB family members (Bos taurus)
Signaling by Activin (Bos taurus)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Bos taurus)
ACVR2A,B [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
Activin A,AB,B:ACVR2A,B:ACVR1B [plasma membrane] (Bos taurus)
ACVR2A,B [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
Activin A,AB,B:ACVR2A,B:p-ACVR1B [plasma membrane] (Bos taurus)
ACVR2A,B [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B (Bos taurus)
ACVR2A,B [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
Activin A,AB,B:ACVR2A,B:ACVR1B [plasma membrane] (Bos taurus)
ACVR2A,B [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
INHIBIN-A:TGFBR3:ACVR2A [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Bos taurus)
Activin:ACVR2A,B:p-ACVR1B,C [plasma membrane] (Bos taurus)
Activin A,AB,B:ACVR2A,B:p-ACVR1B [plasma membrane] (Bos taurus)
ACVR2A,B [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
Activin AB,B:ACVR2A,B:p-ACVR1C [plasma membrane] (Bos taurus)
ACVR2A,B [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
Signaling by BMP (Bos taurus)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Bos taurus)
BMP:p-BMPR:Endofin:SMAD1/5/8 [early endosome membrane] (Bos taurus)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Bos taurus)
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Bos taurus)
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
An anchoring protein, Endofin, recruits R-Smad1/5/8 (Bos taurus)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Bos taurus)
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
BMP:p-BMPR:Endofin:SMAD1/5/8 [early endosome membrane] (Bos taurus)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Bos taurus)
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
BMP2 binds to the receptor complex (Bos taurus)
BMP:BMPRII:BMPRI [plasma membrane] (Bos taurus)
BMPRII:BMPRI [plasma membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Bos taurus)
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
BMPRII:BMPRI [plasma membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Bos taurus)
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
INHIBIN-A:TGFBR3:ACVR2A [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
Formation of a heteromeric BMP receptor complex (Bos taurus)
BMPRII dimer [plasma membrane] (Bos taurus)
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
BMPRII:BMPRI [plasma membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Bos taurus)
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Bos taurus)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Bos taurus)
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
BMP:p-BMPR:I-SMAD:SMURF [plasma membrane] (Bos taurus)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Bos taurus)
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
I-Smad competes with R-Smad1/5/8 for type I receptor (Bos taurus)
BMP2:BMP type II receptor:Phospho-BMP type I receptor:I-SMAD [plasma membrane] (Bos taurus)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Bos taurus)
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Bos taurus)
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
Phospho-R-Smad1/5/8 dissociates from the receptor complex (Bos taurus)
BMP:p-BMPR:Endofin [early endosome membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Bos taurus)
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Bos taurus)
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
Type II receptor phosphorylates type I receptor (Bos taurus)
BMP:BMPRII:BMPRI [plasma membrane] (Bos taurus)
BMPRII:BMPRI [plasma membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Bos taurus)
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Bos taurus)
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
Signaling by TGFBR3 (Bos taurus)
TGFBR3 regulates activin signaling (Bos taurus)
InhibinA-TGFBR3 binding to ACVR2A (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
INHIBIN-A:TGFBR3:ACVR2A [plasma membrane] (Bos taurus)
ACVR2A [plasma membrane] (Bos taurus)
External Reference Information
External Reference
UniProt:Q28043
Reference Genes
BioGPS Gene:281598
ENSEMBL:ENSBTAG00000018114
ENSEMBL:ENSBTAG00000018114.7
KEGG Gene (Bos taurus):281598
Monarch:281598
NCBI Gene:281598
Reference Transcript
RefSeq:NM_174227.3
Other Identifiers
281598
Participates
as an input of
InhibinA-TGFBR3 binding to ACVR2A (Bos taurus)
as a member of
Type II receptor [plasma membrane] (Bos taurus)
ACVR2A,B [plasma membrane] (Bos taurus)
as a component of
INHIBIN-A:TGFBR3:ACVR2A [plasma membrane] (Bos taurus)
Inferred From
ACVR2A [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_776652.1
Ensembl
ENSBTAP00000024108
,
ENSBTAG00000018114
,
ENSBTAT00000024108
VGNC
25595
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