Reactome | CD3D [plasma membrane]

CD3D [plasma membrane]

Stable Identifier

R-BTA-198171

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

plasma membrane

Synonyms

CD3D, Q28072

Locations in the PathwayBrowser

Expand all

Immune System (Bos taurus)

- Adaptive Immune System (Bos taurus)
  - Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Bos taurus)
    - TCR binds microbial lipid-based antigen via CD1 (Bos taurus)
      - CD1:B2M:microbial lipid:TCR [plasma membrane] (Bos taurus)
        
        T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
      - T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
    - TCR binds self-lipid-based antigen via CD1 (Bos taurus)
      - CD1:B2M:self-lipid:TCR [plasma membrane] (Bos taurus)
        
        T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
      - T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
    - TCR complex interacts with peptide antigen-presenting MHC Class I (Bos taurus)
      - T-cell receptor complex with CD8 [plasma membrane] (Bos taurus)
        
        T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
      - TCR interacting with antigen-bearing MHC Class I [plasma membrane] (Bos taurus)
        
        T-cell receptor complex with CD8 [plasma membrane] (Bos taurus)
        
        T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
  - TCR signaling (Bos taurus)
    - Downstream TCR signaling (Bos taurus)
      - Change of PKC theta conformation (Bos taurus)
        
        Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Bos taurus)
        
        T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
    - Phosphorylation of CD3 and TCR zeta chains (Bos taurus)
      - Activation of Lck (Bos taurus)
        
        Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Bos taurus)
        
        T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
        
        Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Bos taurus)
        
        T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
      - Dephosphorylation of Lck-pY505 by CD45 (Bos taurus)
        
        Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Bos taurus)
        
        T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
        
        Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Bos taurus)
        
        T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
      - Inactivation of LCK by PTPN22 (Bos taurus)
        
        Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Bos taurus)
        
        T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
        
        Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Bos taurus)
        
        T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
      - Inactivation of Lck by Csk (Bos taurus)
        
        Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Bos taurus)
        
        T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
        
        Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Bos taurus)
        
        T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
      - Phosphorylation of ITAM motifs in CD3 complexes (Bos taurus)
        
        Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Bos taurus)
        
        T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
    - Translocation of ZAP-70 to Immunological synapse (Bos taurus)
      - Phosphorylation of ZAP-70 by Lck (Bos taurus)
        
        Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Bos taurus)
        
        T-cell receptor complex [plasma membrane] (Bos taurus)
        
        CD3 epsilon delta [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)

Vesicle-mediated transport (Bos taurus)

- Membrane Trafficking (Bos taurus)
  - Clathrin-mediated endocytosis (Bos taurus)
    - BAR domain proteins recruit dynamin (Bos taurus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
    - CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Bos taurus)
      - CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
    - Cargo recognition for clathrin-mediated endocytosis (Bos taurus)
      - AP-2 directly binds some endocytic cargo (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
    - Clathrin recruits PIK3C2A (Bos taurus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
    - Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Bos taurus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Bos taurus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Bos taurus)
        
        CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
    - Endophilins recruit synaptojanins to the clathrin-coated pit (Bos taurus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
    - F- and N- BAR domain proteins bind the clathrin-coated pit (Bos taurus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
    - SNX9 recruits components of the actin polymerizing machinery (Bos taurus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
    - SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Bos taurus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Bos taurus)
        
        CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        CLASP proteins:cargo [plasma membrane] (Bos taurus)
        
        AP-2:cargo [plasma membrane] (Bos taurus)
        
        AP-2 cargo [plasma membrane] (Bos taurus)
        
        AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)
        
        CD3D [plasma membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:Q28072

Gene Names

CD3D

Reference Genes

BioGPS Gene:281053 CD3D

ENSEMBL:ENSBTAG00000006452

ENSEMBL:ENSBTAG00000006452.6 CD3D

KEGG Gene (Bos taurus):281053 CD3D

Monarch:281053 CD3D

NCBI Gene:281053 CD3D

Reference Transcript

RefSeq:NM_001034033.2 CD3D

Other Identifiers

281053

GO:0002250

GO:0002376

GO:0004888

GO:0005886

GO:0007166

GO:0009897

GO:0016020

GO:0023052

GO:0030154

GO:0042105

GO:0045059

GO:0048856

GO:0060089

Participates

as a member of

AP-2 dileucine-containing cargo [plasma membrane] (Bos taurus)

as a component of

CD3 epsilon delta [plasma membrane] (Bos taurus)

Other forms of this molecule

CD3D [clathrin-coated endocytic vesicle membrane]

phospho-CD3D [plasma membrane]

Inferred From

CD3D [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001029205.1

OpenTargets

ENSG00000167286

Ensembl

ENSBTAP00000008462, ENSBTAT00000008462, ENSBTAG00000006452

VGNC

27028

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