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phospho-SPRY2 [cytosol]
Stable Identifier
R-BTA-182950
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
p-Y55-SPRY2, Q08E39
Locations in the PathwayBrowser
Expand all
Signal Transduction (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by EGFR (Bos taurus)
EGFR downregulation (Bos taurus)
CBL binds and ubiquitinates phosphorylated Sprouty (Bos taurus)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Bos taurus)
Ub-p-Y53/55-SPRY1/2 [cytosol] (Bos taurus)
p-Y53/55-SPRY1/2 [cytosol] (Bos taurus)
phospho-SPRY2 [cytosol] (Bos taurus)
CBL ubiquitinates Sprouty (Bos taurus)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Bos taurus)
Ub-p-Y53/55-SPRY1/2 [cytosol] (Bos taurus)
p-Y53/55-SPRY1/2 [cytosol] (Bos taurus)
phospho-SPRY2 [cytosol] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:CBL:p-Y53/55-SPRY1/2 [plasma membrane] (Bos taurus)
p-Y53/55-SPRY1/2 [cytosol] (Bos taurus)
phospho-SPRY2 [cytosol] (Bos taurus)
Sprouty lures CBL away from EGFR (Bos taurus)
phospho-SPRY2 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:Q08E39
Gene Names
SPRY2
Reference Genes
BioGPS Gene:539090 SPRY2
ENSEMBL:ENSBTAG00000001774
KEGG:bta:539090 SPRY2
Monarch:539090 SPRY2
NCBI Gene:539090 SPRY2
UCSC:Q08E39 SPRY2
Reference Transcript
RefSeq:NM_001076147.1 SPRY2
RefSeq:XM_005213881.5 SPRY2
Other Identifiers
539090
Bt.18298.1.A1_at
Bt.28178.1.A1_at
GO:0000132
GO:0005634
GO:0005829
GO:0005856
GO:0007010
GO:0007275
GO:0007605
GO:0008285
GO:0008543
GO:0009966
GO:0010628
GO:0010719
GO:0015629
GO:0015630
GO:0016020
GO:0016525
GO:0019901
GO:0030291
GO:0030324
GO:0030335
GO:0030512
GO:0031345
GO:0031397
GO:0035924
GO:0040037
GO:0042059
GO:0042472
GO:0043066
GO:0043539
GO:0045165
GO:0045742
GO:0046580
GO:0048754
GO:0048856
GO:0050877
GO:0051387
GO:0051897
GO:0055105
GO:0060425
GO:0060437
GO:0060449
GO:0060541
GO:0070371
GO:0070373
GO:0070374
GO:0098772
GO:0140678
GO:1900747
GO:1902747
GO:1990752
GO:1990830
Participates
as a member of
p-Y53/55-SPRY1/2 [cytosol] (Bos taurus)
as an input of
Sprouty lures CBL away from EGFR (Bos taurus)
Other forms of this molecule
phospho-SPRY2 [cytosol]
phospho-SPRY2 [plasma membrane]
phospho-SPRY2 [plasma membrane]
SPRY2 [plasma membrane]
SPRY2 [cytosol]
phospho-SPRY2 [cytosol]
Inferred From
p-Y55-SPRY2 [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 55 (in Homo sapiens)
Coordinate
55
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
XP_005213938.1
,
NP_001069615.1
ENSEMBL
ENSBTAT00000120651
,
ENSBTAT00000121631
,
ENSBTAP00000078798
,
ENSBTAT00000095934
,
ENSBTAP00000043748
,
ENSBTAP00000090374
,
ENSBTAT00000110719
,
ENSBTAP00000095855
,
ENSBTAT00000002324
,
ENSBTAP00000081341
,
ENSBTAP00000084199
,
ENSBTAG00000001774
,
ENSBTAT00000134385
VGNC
35242
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