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SPRY2 [plasma membrane]
Stable Identifier
R-BTA-182924
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
plasma membrane
Synonyms
SPRY2, Q08E39
Locations in the PathwayBrowser
Expand all
Signal Transduction (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by EGFR (Bos taurus)
EGFR downregulation (Bos taurus)
Sprouty sequesters CBL away from active EGFR (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:SPRY1/2:Endophilin:Epsin:Eps15L1:EPS15 [plasma membrane] (Bos taurus)
SPRY1/2 [plasma membrane] (Bos taurus)
SPRY2 [plasma membrane] (Bos taurus)
SPRY1/2 [plasma membrane] (Bos taurus)
SPRY2 [plasma membrane] (Bos taurus)
Signaling by FGFR (Bos taurus)
Signaling by FGFR1 (Bos taurus)
Negative regulation of FGFR1 signaling (Bos taurus)
Spry regulation of FGF signaling (Bos taurus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Bos taurus)
PP2A(A:C):SPRY2 [plasma membrane] (Bos taurus)
SPRY2 [plasma membrane] (Bos taurus)
SPRY2 translocates to the plasma membrane (Bos taurus)
PP2A(A:C):SPRY2 [plasma membrane] (Bos taurus)
SPRY2 [plasma membrane] (Bos taurus)
SRC phosphorylates SPRY2 on Y55 and Y227 (Bos taurus)
PP2A(A:C):SPRY2 [plasma membrane] (Bos taurus)
SPRY2 [plasma membrane] (Bos taurus)
Signaling by FGFR2 (Bos taurus)
Negative regulation of FGFR2 signaling (Bos taurus)
Spry regulation of FGF signaling (Bos taurus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Bos taurus)
PP2A(A:C):SPRY2 [plasma membrane] (Bos taurus)
SPRY2 [plasma membrane] (Bos taurus)
SPRY2 translocates to the plasma membrane (Bos taurus)
PP2A(A:C):SPRY2 [plasma membrane] (Bos taurus)
SPRY2 [plasma membrane] (Bos taurus)
SRC phosphorylates SPRY2 on Y55 and Y227 (Bos taurus)
PP2A(A:C):SPRY2 [plasma membrane] (Bos taurus)
SPRY2 [plasma membrane] (Bos taurus)
Signaling by FGFR3 (Bos taurus)
Negative regulation of FGFR3 signaling (Bos taurus)
Spry regulation of FGF signaling (Bos taurus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Bos taurus)
PP2A(A:C):SPRY2 [plasma membrane] (Bos taurus)
SPRY2 [plasma membrane] (Bos taurus)
SPRY2 translocates to the plasma membrane (Bos taurus)
PP2A(A:C):SPRY2 [plasma membrane] (Bos taurus)
SPRY2 [plasma membrane] (Bos taurus)
SRC phosphorylates SPRY2 on Y55 and Y227 (Bos taurus)
PP2A(A:C):SPRY2 [plasma membrane] (Bos taurus)
SPRY2 [plasma membrane] (Bos taurus)
Signaling by FGFR4 (Bos taurus)
Negative regulation of FGFR4 signaling (Bos taurus)
Spry regulation of FGF signaling (Bos taurus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Bos taurus)
PP2A(A:C):SPRY2 [plasma membrane] (Bos taurus)
SPRY2 [plasma membrane] (Bos taurus)
SPRY2 translocates to the plasma membrane (Bos taurus)
PP2A(A:C):SPRY2 [plasma membrane] (Bos taurus)
SPRY2 [plasma membrane] (Bos taurus)
SRC phosphorylates SPRY2 on Y55 and Y227 (Bos taurus)
PP2A(A:C):SPRY2 [plasma membrane] (Bos taurus)
SPRY2 [plasma membrane] (Bos taurus)
External Reference Information
External Reference
UniProt:Q08E39
Gene Names
SPRY2
Reference Genes
BioGPS Gene:539090 SPRY2
ENSEMBL:ENSBTAG00000001774
ENSEMBL:ENSBTAG00000001774.5 SPRY2
KEGG Gene (Bos taurus):539090 SPRY2
Monarch:539090 SPRY2
NCBI Gene:539090 SPRY2
Reference Transcript
RefSeq:NM_001076147.1 SPRY2
RefSeq:XM_005213881.3 SPRY2
Other Identifiers
539090
GO:0007275
GO:0009966
GO:0016020
GO:0023052
GO:0048856
Participates
as a component of
PP2A(A:C):SPRY2 [plasma membrane] (Bos taurus)
as a member of
SPRY1/2 [plasma membrane] (Bos taurus)
Other forms of this molecule
phospho-SPRY2 [cytosol]
phospho-SPRY2 [plasma membrane]
phospho-SPRY2 [plasma membrane]
phospho-SPRY2 [cytosol]
SPRY2 [cytosol]
phospho-SPRY2 [cytosol]
Inferred From
SPRY2 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
XP_005213938.1
,
NP_001069615.1
OpenTargets
ENSG00000136158
Ensembl
ENSBTAG00000001774
,
ENSBTAP00000043748
,
ENSBTAT00000002324
VGNC
35242
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