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AURKA [cytosol]
Stable Identifier
R-BTA-174254
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
AURKA, Q2TA06
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
Mitotic G2-G2/M phases (Bos taurus)
G2/M Transition (Bos taurus)
AURKA Activation by TPX2 (Bos taurus)
TPX2 binds AURKA at centrosomes (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
AURKA [cytosol] (Bos taurus)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
AURKA [cytosol] (Bos taurus)
TPX2 promotes AURKA autophosphorylation (Bos taurus)
AURKA [cytosol] (Bos taurus)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
AURKA [cytosol] (Bos taurus)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Bos taurus)
SCF-FBXL7 ubiquitinates AURKA (Bos taurus)
SCF-FBXL7:AURKA [cytosol] (Bos taurus)
AURKA [cytosol] (Bos taurus)
SCF:FBXL7 binds AURKA (Bos taurus)
AURKA [cytosol] (Bos taurus)
SCF-FBXL7:AURKA [cytosol] (Bos taurus)
AURKA [cytosol] (Bos taurus)
Interaction between PHLDA1 and AURKA (Bos taurus)
AURKA phosphorylates PHLDA1 (Bos taurus)
AURKA [cytosol] (Bos taurus)
AURKA:PHLDA1 [cytosol] (Bos taurus)
AURKA [cytosol] (Bos taurus)
PHLDA1 binds AURKA (Bos taurus)
AURKA [cytosol] (Bos taurus)
AURKA:PHLDA1 [cytosol] (Bos taurus)
AURKA [cytosol] (Bos taurus)
Regulation of PLK1 Activity at G2/M Transition (Bos taurus)
AJUBA binds centrosome-associated AURKA (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
AURKA [cytosol] (Bos taurus)
Centrosome:AURKA:AJUBA [cytosol] (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
AURKA [cytosol] (Bos taurus)
AJUBA facilitates AURKA autophosphorylation (Bos taurus)
AURKA [cytosol] (Bos taurus)
Centrosome:AURKA:AJUBA [cytosol] (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
AURKA [cytosol] (Bos taurus)
Regulation of mitotic cell cycle (Bos taurus)
APC/C-mediated degradation of cell cycle proteins (Bos taurus)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Bos taurus)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Bos taurus)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Bos taurus)
AURKA [cytosol] (Bos taurus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Bos taurus)
AURKA [cytosol] (Bos taurus)
Degradation of multiubiquitinated cell cycle proteins (Bos taurus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Bos taurus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Bos taurus)
AURKA [cytosol] (Bos taurus)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Bos taurus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Bos taurus)
AURKA [cytosol] (Bos taurus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Bos taurus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Bos taurus)
AURKA [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:Q2TA06
Gene Names
AURKA
Reference Genes
BioGPS Gene:504437 AURKA
ENSEMBL:ENSBTAG00000013009
KEGG:bta:504437 AURKA
Monarch:504437 AURKA
NCBI Gene:504437 AURKA
UCSC:Q2TA06 AURKA
Reference Transcript
RefSeq:NM_001038028.1 AURKA
RefSeq:XM_005214525.5 AURKA
Other Identifiers
504437
Bt.26683.1.S1_at
Bt.26683.2.S1_at
GO:0000212
GO:0000226
GO:0000278
GO:0000922
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0005634
GO:0005654
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0005876
GO:0006468
GO:0006915
GO:0007010
GO:0007051
GO:0007052
GO:0007057
GO:0007098
GO:0007100
GO:0009611
GO:0009948
GO:0010629
GO:0014069
GO:0015630
GO:0016740
GO:0019901
GO:0022414
GO:0030163
GO:0031616
GO:0031625
GO:0031647
GO:0032436
GO:0035175
GO:0036064
GO:0042585
GO:0043066
GO:0043161
GO:0043203
GO:0043226
GO:0044782
GO:0045120
GO:0046982
GO:0048471
GO:0048856
GO:0051321
GO:0051642
GO:0061523
GO:0071539
GO:0072686
GO:0072687
GO:0090141
GO:0097421
GO:0097431
GO:0098978
GO:0140096
GO:1900195
GO:1990138
Participates
as an input of
SCF:FBXL7 binds AURKA (Bos taurus)
PHLDA1 binds AURKA (Bos taurus)
as a component of
SCF-FBXL7:AURKA [cytosol] (Bos taurus)
AURKA:PHLDA1 [cytosol] (Bos taurus)
Centrosome:AURKA [cytosol] (Bos taurus)
as an output of
AURKA phosphorylates PHLDA1 (Bos taurus)
as a member of
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Bos taurus)
Other forms of this molecule
phospho-AURKA [nucleoplasm]
AURKA [nucleoplasm]
AURKA [cytosol]
phospho-AURKA [cytosol]
Inferred From
AURKA [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_005214582.1
,
NP_001033117.1
ENSEMBL
ENSBTAG00000013009
,
ENSBTAP00000042073
,
ENSBTAT00000044590
VGNC
26349
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