Reactome | C1R C-terminal fragment [extracellular region]

C1R C-terminal fragment [extracellular region]

Stable Identifier

R-BTA-173603

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

extracellular region

Synonyms

A0A3Q1MGP1

Locations in the PathwayBrowser

Expand all

Immune System (Bos taurus)

- Innate Immune System (Bos taurus)
  - Complement cascade (Bos taurus)
    - Initial triggering of complement (Bos taurus)
      - Conversion of C2 into C2a and C2b (Bos taurus)
        
        C4 activators [plasma membrane] (Bos taurus)
        
        Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Bos taurus)
        
        C1Q:2x Activated C1R:2x Activated C1S [extracellular region] (Bos taurus)
        
        2x Activated C1R:2x Activated C1S [extracellular region] (Bos taurus)
        
        Activated C1R [extracellular region] (Bos taurus)
        
        C1R C-terminal fragment [extracellular region] (Bos taurus)
      - Conversion of C4 into C4a and C4b (Bos taurus)
        
        C4 activators [plasma membrane] (Bos taurus)
        
        Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Bos taurus)
        
        C1Q:2x Activated C1R:2x Activated C1S [extracellular region] (Bos taurus)
        
        2x Activated C1R:2x Activated C1S [extracellular region] (Bos taurus)
        
        Activated C1R [extracellular region] (Bos taurus)
        
        C1R C-terminal fragment [extracellular region] (Bos taurus)
      - Creation of C4 and C2 activators (Bos taurus)
        
        Classical antibody-mediated complement activation (Bos taurus)
        
        Activation of C1r (Bos taurus)
        
        Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Bos taurus)
        
        C1Q:2x Activated C1R:2xC1S [extracellular region] (Bos taurus)
        
        2x Activated C1R:2xC1S [extracellular region] (Bos taurus)
        
        Activated C1R [extracellular region] (Bos taurus)
        
        C1R C-terminal fragment [extracellular region] (Bos taurus)
        
        Activation of C1s (Bos taurus)
        
        Activated C1R [extracellular region] (Bos taurus)
        
        C1R C-terminal fragment [extracellular region] (Bos taurus)
        
        Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Bos taurus)
        
        C1Q:2x Activated C1R:2x Activated C1S [extracellular region] (Bos taurus)
        
        2x Activated C1R:2x Activated C1S [extracellular region] (Bos taurus)
        
        Activated C1R [extracellular region] (Bos taurus)
        
        C1R C-terminal fragment [extracellular region] (Bos taurus)
        
        Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Bos taurus)
        
        C1Q:2x Activated C1R:2xC1S [extracellular region] (Bos taurus)
        
        2x Activated C1R:2xC1S [extracellular region] (Bos taurus)
        
        Activated C1R [extracellular region] (Bos taurus)
        
        C1R C-terminal fragment [extracellular region] (Bos taurus)
    - Regulation of Complement cascade (Bos taurus)
      - Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Bos taurus)
        
        Activated C1R:SERPING1 [extracellular region] (Bos taurus)
        
        Activated C1R [extracellular region] (Bos taurus)
        
        C1R C-terminal fragment [extracellular region] (Bos taurus)
        
        Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Bos taurus)
        
        2x Activated C1R:SERPING1:2x Activated C1S:SERPING1 [extracellular region] (Bos taurus)
        
        Activated C1R:SERPING1 [extracellular region] (Bos taurus)
        
        Activated C1R [extracellular region] (Bos taurus)
        
        C1R C-terminal fragment [extracellular region] (Bos taurus)
      - C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Bos taurus)
        
        Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Bos taurus)
        
        C1Q:2x Activated C1R:2x Activated C1S [extracellular region] (Bos taurus)
        
        2x Activated C1R:2x Activated C1S [extracellular region] (Bos taurus)
        
        Activated C1R [extracellular region] (Bos taurus)
        
        C1R C-terminal fragment [extracellular region] (Bos taurus)
        
        Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Bos taurus)
        
        Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Bos taurus)
        
        C1Q:2x Activated C1R:2x Activated C1S [extracellular region] (Bos taurus)
        
        2x Activated C1R:2x Activated C1S [extracellular region] (Bos taurus)
        
        Activated C1R [extracellular region] (Bos taurus)
        
        C1R C-terminal fragment [extracellular region] (Bos taurus)
      - C1-Inh binds and inactivates C1r, C1s (Bos taurus)
        
        Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Bos taurus)
        
        Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Bos taurus)
        
        C1Q:2x Activated C1R:2x Activated C1S [extracellular region] (Bos taurus)
        
        2x Activated C1R:2x Activated C1S [extracellular region] (Bos taurus)
        
        Activated C1R [extracellular region] (Bos taurus)
        
        C1R C-terminal fragment [extracellular region] (Bos taurus)
        
        Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Bos taurus)
        
        2x Activated C1R:SERPING1:2x Activated C1S:SERPING1 [extracellular region] (Bos taurus)
        
        Activated C1R:SERPING1 [extracellular region] (Bos taurus)
        
        Activated C1R [extracellular region] (Bos taurus)
        
        C1R C-terminal fragment [extracellular region] (Bos taurus)

External Reference Information

External Reference

UniProt:A0A3Q1MGP1

Reference Genes

BioGPS Gene:511581

ENSEMBL:ENSBTAG00000008612.5

Monarch:511581

NCBI Gene:511581

Reference Transcript

RefSeq:XM_005207128.2

Other Identifiers

511581

GO:0002376

GO:0003824

GO:0004252

GO:0005509

GO:0005576

GO:0005615

GO:0006508

GO:0006956

GO:0008236

GO:0016787

GO:0031638

GO:0045087

GO:0051604

GO:0098542

GO:0140096

Participates

as a component of

Activated C1R [extracellular region] (Bos taurus)

Other forms of this molecule

C1R(18-705) [extracellular region]

C1R N-terminal fragment [extracellular region]

Inferred From

C1R C-terminal fragment [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_005207185.1

Ensembl

ENSBTAP00000069754, ENSBTAT00000073935, ENSBTAG00000008612

VGNC

56194

Cite Us!