Reactome | GNAT2 [plasma membrane]

GNAT2 [plasma membrane]

Stable Identifier

R-BTA-167417

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

plasma membrane

Synonyms

P04696

Locations in the PathwayBrowser

Expand all

Signal Transduction (Bos taurus)

- Signaling by GPCR (Bos taurus)
  - GPCR downstream signalling (Bos taurus)
    - G alpha (i) signalling events (Bos taurus)
      - G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) (Bos taurus)
        
        G-alpha(t)-GTP [plasma membrane] (Bos taurus)
        
        G-protein alpha (t) subunit [plasma membrane] (Bos taurus)
        
        GNAT2 [plasma membrane] (Bos taurus)
        
        G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Bos taurus)
        
        G-alpha(t)-GTP:G-beta-gamma [plasma membrane] (Bos taurus)
        
        G-alpha(t)-GTP [plasma membrane] (Bos taurus)
        
        G-protein alpha (t) subunit [plasma membrane] (Bos taurus)
        
        GNAT2 [plasma membrane] (Bos taurus)
      - Opsins act as GEFs for G alpha-t (Bos taurus)
        
        G-alpha(t):GDP:G-beta-gamma:Opsins [plasma membrane] (Bos taurus)
        
        G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (Bos taurus)
        
        G-alpha(t)-GDP [plasma membrane] (Bos taurus)
        
        G-protein alpha (t) subunit [plasma membrane] (Bos taurus)
        
        GNAT2 [plasma membrane] (Bos taurus)
        
        G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Bos taurus)
        
        G-alpha(t)-GTP:G-beta-gamma [plasma membrane] (Bos taurus)
        
        G-alpha(t)-GTP [plasma membrane] (Bos taurus)
        
        G-protein alpha (t) subunit [plasma membrane] (Bos taurus)
        
        GNAT2 [plasma membrane] (Bos taurus)
      - Opsins binds G alpha-t (Bos taurus)
        
        G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (Bos taurus)
        
        G-alpha(t)-GDP [plasma membrane] (Bos taurus)
        
        G-protein alpha (t) subunit [plasma membrane] (Bos taurus)
        
        GNAT2 [plasma membrane] (Bos taurus)
        
        G-alpha(t):GDP:G-beta-gamma:Opsins [plasma membrane] (Bos taurus)
        
        G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (Bos taurus)
        
        G-alpha(t)-GDP [plasma membrane] (Bos taurus)
        
        G-protein alpha (t) subunit [plasma membrane] (Bos taurus)
        
        GNAT2 [plasma membrane] (Bos taurus)
- Signaling by WNT (Bos taurus)
  - Beta-catenin independent WNT signaling (Bos taurus)
    - Ca2+ pathway (Bos taurus)
      - G-protein subunits dissociate from WNT:FZD complex (Bos taurus)
        
        G-protein alpha (o/t2) [plasma membrane] (Bos taurus)
        
        GNAT2 [plasma membrane] (Bos taurus)
        
        WNT5A/11:FZD:G-protein (alpha o/t2) active [plasma membrane] (Bos taurus)
        
        G-protein alpha (o/t2):GTP [plasma membrane] (Bos taurus)
        
        G-protein alpha (o/t2) [plasma membrane] (Bos taurus)
        
        GNAT2 [plasma membrane] (Bos taurus)
      - PDE6 hydrolyses cGMP to GMP (Bos taurus)
        
        GNAT2:PDE6 [plasma membrane] (Bos taurus)
        
        GNAT2:GTP [plasma membrane] (Bos taurus)
        
        GNAT2 [plasma membrane] (Bos taurus)
      - WNT:FZD complex promotes G-protein nucleotide exchange (Bos taurus)
        
        WNT5A/11:FZD:G-protein (alpha o/t2) active [plasma membrane] (Bos taurus)
        
        G-protein alpha (o/t2):GTP [plasma membrane] (Bos taurus)
        
        G-protein alpha (o/t2) [plasma membrane] (Bos taurus)
        
        GNAT2 [plasma membrane] (Bos taurus)
        
        WNT5A/11:FZD:G-protein (alpha o/t2) inactive [plasma membrane] (Bos taurus)
        
        Heterotrimeric G-protein (o/t2) (inactive) [plasma membrane] (Bos taurus)
        
        G-protein alpha (o/t2):GDP [plasma membrane] (Bos taurus)
        
        G-protein alpha (o/t2) [plasma membrane] (Bos taurus)
        
        GNAT2 [plasma membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:P04696

Reference Genes

BioGPS Gene:281795

ENSEMBL:ENSBTAG00000013017

ENSEMBL:ENSBTAG00000013017.4

KEGG Gene (Bos taurus):281795

Monarch:281795

NCBI Gene:281795

Reference Transcript

RefSeq:NM_174326.2

Other Identifiers

GO:0000166

GO:0000902

GO:0001580

GO:0001664

GO:0001750

GO:0001917

GO:0003824

GO:0003924

GO:0005525

GO:0005834

GO:0005886

GO:0005929

GO:0006954

GO:0007165

GO:0007186

GO:0007188

GO:0007601

GO:0007602

GO:0007632

GO:0008104

GO:0009411

GO:0009416

GO:0009583

GO:0009642

GO:0010467

GO:0014070

GO:0016787

GO:0019001

GO:0023052

GO:0030154

GO:0031683

GO:0042417

GO:0042622

GO:0042670

GO:0042995

GO:0043010

GO:0043226

GO:0045202

GO:0046549

GO:0046872

GO:0048771

GO:0048856

GO:0048877

GO:0050877

GO:0050896

GO:0050908

GO:0051938

GO:0060221

GO:0097719

GO:0120302

GO:0150103

GO:1904390

Participates

as a member of

as a component of

GNAT2:GTP [plasma membrane] (Bos taurus)

Inferred From

GNAT2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_776751.1

Ensembl

ENSBTAG00000013017, ENSBTAP00000017305, ENSBTAT00000017305

VGNC

29455

PDB

6PH7, 6PGS