Reactome | NDUFA9:FAD [mitochondrial matrix]

NDUFA9:FAD [mitochondrial matrix]

Stable Identifier

R-BTA-164289

Type

Complex

Species

Bos taurus

Compartment

mitochondrial matrix

Locations in the PathwayBrowser

Expand all

Metabolism (Bos taurus)

- Aerobic respiration and respiratory electron transport (Bos taurus)
  - Respiratory electron transport (Bos taurus)
    - Complex I biogenesis (Bos taurus)
      - IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 (Bos taurus)
        
        IP subcomplex [mitochondrial matrix] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)
        
        Intermediate 1 [mitochondrial inner membrane] (Bos taurus)
        
        IP subcomplex [mitochondrial matrix] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)
      - Intermediate 1 binds HP subcomplex to form Intermediate 2 (Bos taurus)
        
        Intermediate 1 [mitochondrial inner membrane] (Bos taurus)
        
        IP subcomplex [mitochondrial matrix] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 1 [mitochondrial inner membrane] (Bos taurus)
        
        IP subcomplex [mitochondrial matrix] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)
      - Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Bos taurus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 1 [mitochondrial inner membrane] (Bos taurus)
        
        IP subcomplex [mitochondrial matrix] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 1 [mitochondrial inner membrane] (Bos taurus)
        
        IP subcomplex [mitochondrial matrix] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)
      - ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Bos taurus)
        
        550kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 1 [mitochondrial inner membrane] (Bos taurus)
        
        IP subcomplex [mitochondrial matrix] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)
        
        815kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        550kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 1 [mitochondrial inner membrane] (Bos taurus)
        
        IP subcomplex [mitochondrial matrix] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)
      - NDUF subunits bind to form the IP subcomplex (Bos taurus)
        
        IP subcomplex [mitochondrial matrix] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)
      - Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Bos taurus)
        
        815kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        550kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 1 [mitochondrial inner membrane] (Bos taurus)
        
        IP subcomplex [mitochondrial matrix] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)
        
        980kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        815kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        550kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 1 [mitochondrial inner membrane] (Bos taurus)
        
        IP subcomplex [mitochondrial matrix] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)
      - The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Bos taurus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 1 [mitochondrial inner membrane] (Bos taurus)
        
        IP subcomplex [mitochondrial matrix] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)
        
        550kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 1 [mitochondrial inner membrane] (Bos taurus)
        
        IP subcomplex [mitochondrial matrix] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)
      - The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Bos taurus)
        
        980kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        815kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        550kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 1 [mitochondrial inner membrane] (Bos taurus)
        
        IP subcomplex [mitochondrial matrix] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)
        
        Complex I [mitochondrial inner membrane] (Bos taurus)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 1 (-NDUFAF3,4,7, TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)
    - Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 (Bos taurus)
      - Complex I [mitochondrial inner membrane] (Bos taurus)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 1 (-NDUFAF3,4,7, TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        NDUFA9:FAD [mitochondrial matrix] (Bos taurus)

General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

Participates

as an input of

NDUF subunits bind to form the IP subcomplex (Bos taurus)

as a component of

Inferred From

NDUFA9:FAD [mitochondrial matrix] (Homo sapiens)

Cite Us!