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phospho-LRP6 [plasma membrane]
Stable Identifier
R-BTA-1458895
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
plasma membrane
Synonyms
p-4S,3T,T1479,S1490,T1493-LRP6, F1MDE1
Locations in the PathwayBrowser
Expand all
Signal Transduction (Bos taurus)
Signaling by WNT (Bos taurus)
TCF dependent signaling in response to WNT (Bos taurus)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Bos taurus)
Beta-catenin is released from the destruction complex (Bos taurus)
WNT:FZD:p10S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Bos taurus)
p10S/T-LRP5/6 [plasma membrane] (Bos taurus)
phospho-LRP6 [plasma membrane] (Bos taurus)
WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Bos taurus)
WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [plasma membrane] (Bos taurus)
phospho-LRP6 [plasma membrane] (Bos taurus)
External Reference Information
External Reference
UniProt:F1MDE1
Gene Names
LRP6
Reference Genes
BioGPS Gene:536328 LRP6
ENSEMBL:ENSBTAG00000011761.7
KEGG Gene (Bos taurus):536328 LRP6
Monarch:536328 LRP6
NCBI Gene:536328 LRP6
Reference Transcript
RefSeq:XM_002687783.5 LRP6
RefSeq:XM_015463447.1 LRP6
Other Identifiers
536328
GO:0005515
GO:0005886
GO:0006897
GO:0007268
GO:0016020
GO:0016055
GO:0016192
GO:0017147
GO:0023052
GO:0042813
GO:0045202
GO:0048856
GO:0060070
GO:0060089
GO:0090118
GO:0090244
Participates
as a component of
WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [plasma membrane] (Bos taurus)
as a member of
p10S/T-LRP5/6 [plasma membrane] (Bos taurus)
Other forms of this molecule
LRP6 [early endosome membrane]
phospho-LRP6 [early endosome membrane]
phospho-LRP6 [plasma membrane]
LRP6 [plasma membrane]
Inferred From
p-4S,3T,T1479,S1490,T1493-LRP6 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 1490 (in Homo sapiens)
Coordinate
1490
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 1479 (in Homo sapiens)
Coordinate
1479
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 1493 (in Homo sapiens)
Coordinate
1493
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at unknown position
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at unknown position
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at unknown position
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
XP_015318933.1
,
XP_002687829.2
OpenTargets
ENSG00000070018
Ensembl
ENSBTAG00000011761
,
ENSBTAT00000061164
,
ENSBTAP00000053723
VGNC
30993
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