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POLH [nucleoplasm]
Stable Identifier
R-BTA-110287
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
POLH, F1MZ79
Locations in the PathwayBrowser
Expand all
DNA Repair (Bos taurus)
DNA Damage Bypass (Bos taurus)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Bos taurus)
Termination of translesion DNA synthesis (Bos taurus)
TRIM25 binds monoUb:164-PCNA (Bos taurus)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
DNA polymerase Y [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
DNA polymerase Y [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA (Bos taurus)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
DNA polymerase Y [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
DNA polymerase Y [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
Translesion Synthesis by POLH (Bos taurus)
Elongation by POLH (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
Insertion of correct bases opposite the lesion by POLH (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
RCHY1 binds POLH (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
POLH:RCHY1 [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
RCHY1 monoubiquitinates POLH (Bos taurus)
POLH:RCHY1 [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
SPRTN binds monoUb:K164-PCNA associated with POLH (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Bos taurus)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Bos taurus)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
DNA Double-Strand Break Repair (Bos taurus)
Homology Directed Repair (Bos taurus)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Bos taurus)
HDR through Homologous Recombination (HRR) (Bos taurus)
D-loop extension by DNA polymerases (Bos taurus)
PCNA:POLD,POLE,POLH,POLK:RPA:RFC [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA:RPA:RFC:POLH,POLK [nucleoplasm] (Bos taurus)
POLH,POLK [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:F1MZ79
Gene Names
POLH
Reference Genes
ENSEMBL:ENSBTAG00000006015.5
UCSC:F1MZ79 POLH
Other Identifiers
513606
GO:0000731
GO:0003824
GO:0003887
GO:0005654
GO:0005829
GO:0006281
GO:0006290
GO:0006301
GO:0010225
GO:0016740
GO:0071494
GO:0140097
Participates
as a member of
DNA polymerase Y [nucleoplasm] (Bos taurus)
as an output of
SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Bos taurus)
as an input of
POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Bos taurus)
RCHY1 binds POLH (Bos taurus)
as a component of
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Bos taurus)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Bos taurus)
POLH:RCHY1 [nucleoplasm] (Bos taurus)
as a candidate of
POLH,POLK [nucleoplasm] (Bos taurus)
Other forms of this molecule
POLH [nucleoplasm]
Inferred From
POLH [nucleoplasm]
(Homo sapiens)
Cross References
ENSEMBL
ENSBTAP00000007900
,
ENSBTAT00000007900
VGNC
33124
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