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lef [extracellular region]
Stable Identifier
R-BAN-5205720
Type
Protein [EntityWithAccessionedSequence]
Species
Bacillus anthracis
Compartment
extracellular region
Synonyms
LF, LF(34-809), Lethal factor, lef(34-809)
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Uptake and actions of bacterial toxins (Homo sapiens)
Uptake and function of anthrax toxins (Homo sapiens)
cya and lef bind to pagA(197-794):ANTXR1 oligomer (Homo sapiens)
lef [extracellular region] (Bacillus anthracis)
lef [extracellular region] (Bacillus anthracis)
cya and lef bind to pagA(197-794):ANTXR2 oligomer (Homo sapiens)
lef [extracellular region] (Bacillus anthracis)
lef [extracellular region] (Bacillus anthracis)
Literature References
PubMed ID
Title
Journal
Year
2509294
Nucleotide sequence and analysis of the lethal factor gene (lef) from Bacillus anthracis
Robertson, DL
,
Bragg, TS
Gene
1989
External Reference Information
External Reference
UniProt:P15917 lef
Gene Names
lef, pXO1-107, BXA0172, GBAA_pXO1_0172
Chain
signal peptide:1-33, chain:34-809
Reference Genes
BioGPS Gene:45025515 lef
KEGG Gene (Bacillus anthracis Ames Ancestor):GBAA_pXO1_0172 lef
Monarch:45025515 lef
NCBI Gene:45025515 lef
Reference Transcript
RefSeq:NZ_QPEZ01000014.1 lef
RefSeq:NZ_VTZH01000015.1 lef
RefSeq:NC_001496.1 lef
Participates
as a component of
lef [extracellular region] (Bacillus anthracis)
Other forms of this molecule
lef [cytosol]
LF [endosome membrane]
lef [plasma membrane]
Disease
Name
Identifier
Synonyms
anthrax disease
DOID:7427
Cross References
RefSeq
NP_052803.1
,
WP_001022097.1
,
WP_010890024.1
ZINC - Metabolites
LEF_BACAN
ZINC - World Drugs
LEF_BACAN
IntEnz
3.4.24.83
ZINC - FDA approved
LEF_BACAN
ZINC - Substances
LEF_BACAN
ZINC target
P15917
ZINC - Biogenic
LEF_BACAN
PRO
P15917
ZINC - Predictions - Purchasable
LEF_BACAN
PDB
6ZXJ
,
6ZXK
,
6ZXL
,
4DV8
,
2L0R
,
4WF6
,
1YQY
,
3KWV
,
1PWW
,
1JKY
,
4PKV
,
4PKU
,
1PWU
,
1PWV
,
5D1U
,
4PKT
,
6PSN
,
7KXR
,
1J7N
,
4PKW
,
4XM8
,
4PKQ
,
1PWP
,
4XM7
,
4XM6
,
1ZXV
,
6WJJ
,
5D1T
,
4PKS
,
5D1S
,
4PKR
,
1PWQ
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P13423 pagA
5
pagA [extracellular region]
(R-BAN-5205707)
pagA(30-196) [extracellular region]
(R-BAN-5205700)
pagA [plasma membrane]
(R-BAN-5205702)
PA63 [endosome membrane]
(R-BAN-5210910)
pagA(197-794) [plasma membrane]
(R-BAN-5205715)
0.962
28
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