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moexiprilat [endoplasmic reticulum lumen]
Stable Identifier
R-ALL-9707129
Type
ChemicalDrug
Compartment
endoplasmic reticulum lumen
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism of proteins (Bos taurus)
Peptide hormone metabolism (Bos taurus)
Metabolism of Angiotensinogen to Angiotensins (Bos taurus)
CES1 trimer hydrolyses ACEI pro-drugs to ACEIs (Bos taurus)
hydrolysed ACEIs [endoplasmic reticulum lumen]
moexiprilat [endoplasmic reticulum lumen]
Metabolism of proteins (Caenorhabditis elegans)
Peptide hormone metabolism (Caenorhabditis elegans)
Metabolism of Angiotensinogen to Angiotensins (Caenorhabditis elegans)
CES1 trimer hydrolyses ACEI pro-drugs to ACEIs (Caenorhabditis elegans)
hydrolysed ACEIs [endoplasmic reticulum lumen]
moexiprilat [endoplasmic reticulum lumen]
Metabolism of proteins (Canis familiaris)
Peptide hormone metabolism (Canis familiaris)
Metabolism of Angiotensinogen to Angiotensins (Canis familiaris)
CES1 trimer hydrolyses ACEI pro-drugs to ACEIs (Canis familiaris)
hydrolysed ACEIs [endoplasmic reticulum lumen]
moexiprilat [endoplasmic reticulum lumen]
Metabolism of proteins (Danio rerio)
Peptide hormone metabolism (Danio rerio)
Metabolism of Angiotensinogen to Angiotensins (Danio rerio)
CES1 trimer hydrolyses ACEI pro-drugs to ACEIs (Danio rerio)
hydrolysed ACEIs [endoplasmic reticulum lumen]
moexiprilat [endoplasmic reticulum lumen]
Metabolism of proteins (Dictyostelium discoideum)
Peptide hormone metabolism (Dictyostelium discoideum)
Metabolism of Angiotensinogen to Angiotensins (Dictyostelium discoideum)
CES1 trimer hydrolyses ACEI pro-drugs to ACEIs (Dictyostelium discoideum)
hydrolysed ACEIs [endoplasmic reticulum lumen]
moexiprilat [endoplasmic reticulum lumen]
Metabolism of proteins (Drosophila melanogaster)
Peptide hormone metabolism (Drosophila melanogaster)
Metabolism of Angiotensinogen to Angiotensins (Drosophila melanogaster)
CES1 trimer hydrolyses ACEI pro-drugs to ACEIs (Drosophila melanogaster)
hydrolysed ACEIs [endoplasmic reticulum lumen]
moexiprilat [endoplasmic reticulum lumen]
Metabolism of proteins (Gallus gallus)
Peptide hormone metabolism (Gallus gallus)
Metabolism of Angiotensinogen to Angiotensins (Gallus gallus)
CES1 trimer hydrolyses ACEI pro-drugs to ACEIs (Gallus gallus)
hydrolysed ACEIs [endoplasmic reticulum lumen]
moexiprilat [endoplasmic reticulum lumen]
Metabolism of proteins (Homo sapiens)
Peptide hormone metabolism (Homo sapiens)
Metabolism of Angiotensinogen to Angiotensins (Homo sapiens)
ACEIs translocate from ER lumen to extracellular region (Homo sapiens)
hydrolysed ACEIs [endoplasmic reticulum lumen]
moexiprilat [endoplasmic reticulum lumen]
CES1 trimer hydrolyses ACEI pro-drugs to ACEIs (Homo sapiens)
hydrolysed ACEIs [endoplasmic reticulum lumen]
moexiprilat [endoplasmic reticulum lumen]
Metabolism of proteins (Mus musculus)
Peptide hormone metabolism (Mus musculus)
Metabolism of Angiotensinogen to Angiotensins (Mus musculus)
CES1 trimer hydrolyses ACEI pro-drugs to ACEIs (Mus musculus)
hydrolysed ACEIs [endoplasmic reticulum lumen]
moexiprilat [endoplasmic reticulum lumen]
Metabolism of proteins (Rattus norvegicus)
Peptide hormone metabolism (Rattus norvegicus)
Metabolism of Angiotensinogen to Angiotensins (Rattus norvegicus)
CES1 trimer hydrolyses ACEI pro-drugs to ACEIs (Rattus norvegicus)
hydrolysed ACEIs [endoplasmic reticulum lumen]
moexiprilat [endoplasmic reticulum lumen]
Metabolism of proteins (Sus scrofa)
Peptide hormone metabolism (Sus scrofa)
Metabolism of Angiotensinogen to Angiotensins (Sus scrofa)
CES1 trimer hydrolyses ACEI pro-drugs to ACEIs (Sus scrofa)
hydrolysed ACEIs [endoplasmic reticulum lumen]
moexiprilat [endoplasmic reticulum lumen]
Metabolism of proteins (Xenopus tropicalis)
Peptide hormone metabolism (Xenopus tropicalis)
Metabolism of Angiotensinogen to Angiotensins (Xenopus tropicalis)
CES1 trimer hydrolyses ACEI pro-drugs to ACEIs (Xenopus tropicalis)
hydrolysed ACEIs [endoplasmic reticulum lumen]
moexiprilat [endoplasmic reticulum lumen]
Literature References
PubMed ID
Title
Journal
Year
7473177
Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enalapril
Bao, G
,
Unger, T
,
Gohlke, P
,
Feelisch, M
,
Edling, O
J Pharmacol Exp Ther
1995
15286086
Pharmacological and clinical profile of moexipril: a concise review
Chrysant, SG
,
Chrysant, GS
J Clin Pharmacol
2004
External Reference Information
External Reference
moexiprilat [Guide to Pharmacology:6572]
Participates
as a member of
hydrolysed ACEIs [endoplasmic reticulum lumen]
Other forms of this molecule
moexiprilat [extracellular region]
Disease
Name
Identifier
Synonyms
hypertension
DOID:10763
High blood pressure (& [essential hypertension]), HTN, hypertensive disease, hyperpiesia, vascular hypertensive disorder
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