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amlexanox [cytosol]
Stable Identifier
R-ALL-9679801
Type
ChemicalDrug
Compartment
cytosol
Synonyms
AA-673, Amlexanox®, Aphthasol®, CHX-3673
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
Potential therapeutics for SARS (Homo sapiens)
TBK1 binds amlexanox (Homo sapiens)
amlexanox [cytosol]
TBK1:amlexanox [cytosol] (Homo sapiens)
amlexanox [cytosol]
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Cytosolic sensors of pathogen-associated DNA (Homo sapiens)
ZBP1(DAI) mediated induction of type I IFNs (Homo sapiens)
IRF3 mediated activation of type 1 IFN (Homo sapiens)
Recruitment of IRF3 to activated ZBP1:TBK1 (Homo sapiens)
TBK1:amlexanox [cytosol] (Homo sapiens)
amlexanox [cytosol]
TBK1 binds amlexanox (Homo sapiens)
amlexanox [cytosol]
TBK1:amlexanox [cytosol] (Homo sapiens)
amlexanox [cytosol]
External Reference Information
External Reference
amlexanox [Guide to Pharmacology:7113]
Participates
as an input of
TBK1 binds amlexanox (Homo sapiens)
as a component of
TBK1:amlexanox [cytosol] (Homo sapiens)
Disease
Name
Identifier
Synonyms
aphthous stomatitis
DOID:9663
Oral aphthae, Aphtha, oral ulcer, Oral aphthous ulcer, Canker sore, Aphthous ulceration
allergic rhinitis
DOID:4481
Non-seasonal allergic rhinitis, seasonal allergic rhinitis, atopic rhinitis, hay fever, Perenial allergic rhinitis, pollenosis
asthma
DOID:2841
chronic obstructive asthma with acute exacerbation, chronic obstructive asthma, exercise-induced asthma, chronic obstructive asthma with status asthmaticus, Exercise induced asthma, bronchial hyperreactivity
Cross References
Mondo
0004845
ChEBI
31205
PubChem Compound
178103690
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