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type II KIT binding TKIs [cytosol]
Stable Identifier
R-ALL-9669722
Type
Set [DefinedSet]
Compartment
cytosol
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Signal Transduction (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by SCF-KIT (Bos taurus)
Autophosphorylation of KIT (Bos taurus)
KIT:type II TKIs [plasma membrane] (Bos taurus)
type II KIT binding TKIs [cytosol]
KIT binds type II TKIs (Bos taurus)
type II KIT binding TKIs [cytosol]
KIT:type II TKIs [plasma membrane] (Bos taurus)
type II KIT binding TKIs [cytosol]
Signal Transduction (Caenorhabditis elegans)
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by SCF-KIT (Caenorhabditis elegans)
KIT binds type II TKIs (Caenorhabditis elegans)
type II KIT binding TKIs [cytosol]
KIT:type II TKIs [plasma membrane] (Caenorhabditis elegans)
type II KIT binding TKIs [cytosol]
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by SCF-KIT (Canis familiaris)
Autophosphorylation of KIT (Canis familiaris)
KIT:type II TKIs [plasma membrane] (Canis familiaris)
type II KIT binding TKIs [cytosol]
KIT binds type II TKIs (Canis familiaris)
type II KIT binding TKIs [cytosol]
KIT:type II TKIs [plasma membrane] (Canis familiaris)
type II KIT binding TKIs [cytosol]
Signal Transduction (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by SCF-KIT (Danio rerio)
Autophosphorylation of KIT (Danio rerio)
KIT:type II TKIs [plasma membrane] (Danio rerio)
type II KIT binding TKIs [cytosol]
KIT binds type II TKIs (Danio rerio)
type II KIT binding TKIs [cytosol]
KIT:type II TKIs [plasma membrane] (Danio rerio)
type II KIT binding TKIs [cytosol]
Signal Transduction (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by SCF-KIT (Drosophila melanogaster)
KIT binds type II TKIs (Drosophila melanogaster)
type II KIT binding TKIs [cytosol]
KIT:type II TKIs [plasma membrane] (Drosophila melanogaster)
type II KIT binding TKIs [cytosol]
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by SCF-KIT (Gallus gallus)
Autophosphorylation of KIT (Gallus gallus)
KIT:type II TKIs [plasma membrane] (Gallus gallus)
type II KIT binding TKIs [cytosol]
KIT binds type II TKIs (Gallus gallus)
type II KIT binding TKIs [cytosol]
KIT:type II TKIs [plasma membrane] (Gallus gallus)
type II KIT binding TKIs [cytosol]
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by KIT in disease (Homo sapiens)
KIT mutants bind TKIs (Homo sapiens)
KIT mutants bind type II TKIs (Homo sapiens)
type II KIT binding TKIs [cytosol]
type II sensitive KIT mutants:type II TKIs [plasma membrane] (Homo sapiens)
type II KIT binding TKIs [cytosol]
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by SCF-KIT (Homo sapiens)
Autophosphorylation of KIT (Homo sapiens)
type II KIT binding TKIs [cytosol]
KIT:type II TKIs [plasma membrane] (Homo sapiens)
type II KIT binding TKIs [cytosol]
KIT binds type II TKIs (Homo sapiens)
type II KIT binding TKIs [cytosol]
KIT:type II TKIs [plasma membrane] (Homo sapiens)
type II KIT binding TKIs [cytosol]
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by SCF-KIT (Mus musculus)
Autophosphorylation of KIT (Mus musculus)
KIT:type II TKIs [plasma membrane] (Mus musculus)
type II KIT binding TKIs [cytosol]
KIT binds type II TKIs (Mus musculus)
type II KIT binding TKIs [cytosol]
KIT:type II TKIs [plasma membrane] (Mus musculus)
type II KIT binding TKIs [cytosol]
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by SCF-KIT (Rattus norvegicus)
Autophosphorylation of KIT (Rattus norvegicus)
KIT:type II TKIs [plasma membrane] (Rattus norvegicus)
type II KIT binding TKIs [cytosol]
KIT binds type II TKIs (Rattus norvegicus)
type II KIT binding TKIs [cytosol]
KIT:type II TKIs [plasma membrane] (Rattus norvegicus)
type II KIT binding TKIs [cytosol]
Signal Transduction (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by SCF-KIT (Sus scrofa)
Autophosphorylation of KIT (Sus scrofa)
KIT:type II TKIs [plasma membrane] (Sus scrofa)
type II KIT binding TKIs [cytosol]
KIT binds type II TKIs (Sus scrofa)
type II KIT binding TKIs [cytosol]
KIT:type II TKIs [plasma membrane] (Sus scrofa)
type II KIT binding TKIs [cytosol]
Signal Transduction (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by SCF-KIT (Xenopus tropicalis)
Autophosphorylation of KIT (Xenopus tropicalis)
KIT:type II TKIs [plasma membrane] (Xenopus tropicalis)
type II KIT binding TKIs [cytosol]
KIT binds type II TKIs (Xenopus tropicalis)
type II KIT binding TKIs [cytosol]
KIT:type II TKIs [plasma membrane] (Xenopus tropicalis)
type II KIT binding TKIs [cytosol]
Participants
members
imatinib [cytosol]
sunitinib [cytosol]
regorafenib [cytosol]
sorafenib [cytosol]
nilotinib [cytosol]
ponatinib [cytosol]
masitinib [cytosol]
dasatinib [cytosol]
cabozantinib [cytosol]
axitinib [cytosol]
lenvatinib [cytosol]
Participates
as a component of
type II sensitive KIT mutants:type II TKIs [plasma membrane] (Homo sapiens)
KIT:type II TKIs [plasma membrane] (Mus musculus)
KIT:type II TKIs [plasma membrane] (Xenopus tropicalis)
KIT:type II TKIs [plasma membrane] (Bos taurus)
KIT:type II TKIs [plasma membrane] (Sus scrofa)
KIT:type II TKIs [plasma membrane] (Gallus gallus)
KIT:type II TKIs [plasma membrane] (Rattus norvegicus)
KIT:type II TKIs [plasma membrane] (Caenorhabditis elegans)
KIT:type II TKIs [plasma membrane] (Drosophila melanogaster)
KIT:type II TKIs [plasma membrane] (Danio rerio)
KIT:type II TKIs [plasma membrane] (Homo sapiens)
KIT:type II TKIs [plasma membrane] (Canis familiaris)
as an input of
KIT mutants bind type II TKIs (Homo sapiens)
KIT binds type II TKIs (Drosophila melanogaster)
KIT binds type II TKIs (Gallus gallus)
KIT binds type II TKIs (Xenopus tropicalis)
KIT binds type II TKIs (Danio rerio)
KIT binds type II TKIs (Sus scrofa)
KIT binds type II TKIs (Bos taurus)
KIT binds type II TKIs (Canis familiaris)
KIT binds type II TKIs (Rattus norvegicus)
KIT binds type II TKIs (Mus musculus)
KIT binds type II TKIs (Homo sapiens)
KIT binds type II TKIs (Caenorhabditis elegans)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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