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type I KIT binding TKIs [cytosol]
Stable Identifier
R-ALL-9669710
Type
Set [DefinedSet]
Compartment
cytosol
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Signal Transduction (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by SCF-KIT (Bos taurus)
Autophosphorylation of KIT (Bos taurus)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Bos taurus)
type I KIT binding TKIs [cytosol]
KIT binds type I TKIs (Bos taurus)
type I KIT binding TKIs [cytosol]
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Bos taurus)
type I KIT binding TKIs [cytosol]
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by SCF-KIT (Canis familiaris)
Autophosphorylation of KIT (Canis familiaris)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Canis familiaris)
type I KIT binding TKIs [cytosol]
KIT binds type I TKIs (Canis familiaris)
type I KIT binding TKIs [cytosol]
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Canis familiaris)
type I KIT binding TKIs [cytosol]
Signal Transduction (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by SCF-KIT (Danio rerio)
Autophosphorylation of KIT (Danio rerio)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Danio rerio)
type I KIT binding TKIs [cytosol]
KIT binds type I TKIs (Danio rerio)
type I KIT binding TKIs [cytosol]
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Danio rerio)
type I KIT binding TKIs [cytosol]
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by SCF-KIT (Gallus gallus)
Autophosphorylation of KIT (Gallus gallus)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Gallus gallus)
type I KIT binding TKIs [cytosol]
KIT binds type I TKIs (Gallus gallus)
type I KIT binding TKIs [cytosol]
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Gallus gallus)
type I KIT binding TKIs [cytosol]
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by KIT in disease (Homo sapiens)
KIT mutants bind TKIs (Homo sapiens)
KIT mutants bind type I TKIs (Homo sapiens)
type I KIT binding TKIs [cytosol]
type I sensitive KIT mutants:type I TKIs [plasma membrane] (Homo sapiens)
type I KIT binding TKIs [cytosol]
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by SCF-KIT (Homo sapiens)
Autophosphorylation of KIT (Homo sapiens)
type I KIT binding TKIs [cytosol]
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Homo sapiens)
type I KIT binding TKIs [cytosol]
KIT binds type I TKIs (Homo sapiens)
type I KIT binding TKIs [cytosol]
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Homo sapiens)
type I KIT binding TKIs [cytosol]
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by SCF-KIT (Mus musculus)
Autophosphorylation of KIT (Mus musculus)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Mus musculus)
type I KIT binding TKIs [cytosol]
KIT binds type I TKIs (Mus musculus)
type I KIT binding TKIs [cytosol]
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Mus musculus)
type I KIT binding TKIs [cytosol]
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by SCF-KIT (Rattus norvegicus)
Autophosphorylation of KIT (Rattus norvegicus)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Rattus norvegicus)
type I KIT binding TKIs [cytosol]
KIT binds type I TKIs (Rattus norvegicus)
type I KIT binding TKIs [cytosol]
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Rattus norvegicus)
type I KIT binding TKIs [cytosol]
Signal Transduction (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by SCF-KIT (Sus scrofa)
Autophosphorylation of KIT (Sus scrofa)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Sus scrofa)
type I KIT binding TKIs [cytosol]
KIT binds type I TKIs (Sus scrofa)
type I KIT binding TKIs [cytosol]
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Sus scrofa)
type I KIT binding TKIs [cytosol]
Signal Transduction (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by SCF-KIT (Xenopus tropicalis)
Autophosphorylation of KIT (Xenopus tropicalis)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Xenopus tropicalis)
type I KIT binding TKIs [cytosol]
KIT binds type I TKIs (Xenopus tropicalis)
type I KIT binding TKIs [cytosol]
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Xenopus tropicalis)
type I KIT binding TKIs [cytosol]
Participants
members
dovitinib [cytosol]
midostaurin [cytosol]
avapritinib [cytosol]
Participates
as a component of
type I sensitive KIT mutants:type I TKIs [plasma membrane] (Homo sapiens)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Xenopus tropicalis)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Bos taurus)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Mus musculus)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Sus scrofa)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Rattus norvegicus)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Gallus gallus)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Danio rerio)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Homo sapiens)
KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane] (Canis familiaris)
as an input of
KIT mutants bind type I TKIs (Homo sapiens)
KIT binds type I TKIs (Gallus gallus)
KIT binds type I TKIs (Xenopus tropicalis)
KIT binds type I TKIs (Danio rerio)
KIT binds type I TKIs (Sus scrofa)
KIT binds type I TKIs (Bos taurus)
KIT binds type I TKIs (Canis familiaris)
KIT binds type I TKIs (Rattus norvegicus)
KIT binds type I TKIs (Mus musculus)
KIT binds type I TKIs (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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