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pertuzumab [extracellular region]
Stable Identifier
R-ALL-9665971
Type
ProteinDrug
Compartment
extracellular region
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Canis familiaris
Mus musculus
Expand all
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by ERBB2 (Canis familiaris)
ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 (Canis familiaris)
ERBB2:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Canis familiaris)
ERBB2:pertuzumab [plasma membrane] (Canis familiaris)
pertuzumab [extracellular region]
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by ERBB2 in Cancer (Homo sapiens)
Drug resistance in ERBB2 TMD/JMD mutants (Homo sapiens)
ERBB2 TMD/JMD mutants do not bind pertuzumab (Homo sapiens)
pertuzumab [extracellular region]
Signaling by ERBB2 TMD/JMD mutants (Homo sapiens)
ERBB2 TMD/JMD mutants bind pertuzumab (Homo sapiens)
pertuzumab [extracellular region]
ERBB2 R678Q:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 R678Q:pertuzumab [plasma membrane] (Homo sapiens)
pertuzumab [extracellular region]
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by ERBB2 (Homo sapiens)
Drug-mediated inhibition of ERBB2 signaling (Homo sapiens)
ERBB2 binds pertuzumab (Homo sapiens)
pertuzumab [extracellular region]
ERBB2:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2:pertuzumab [plasma membrane] (Homo sapiens)
pertuzumab [extracellular region]
ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 (Homo sapiens)
pertuzumab [extracellular region]
ERBB2:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2:pertuzumab [plasma membrane] (Homo sapiens)
pertuzumab [extracellular region]
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by ERBB2 (Mus musculus)
ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 (Mus musculus)
ERBB2:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
ERBB2:pertuzumab [plasma membrane] (Mus musculus)
pertuzumab [extracellular region]
External Reference Information
External Reference
pertuzumab [Guide to Pharmacology:5046]
Participates
as an input of
ERBB2 TMD/JMD mutants do not bind pertuzumab (Homo sapiens)
ERBB2 TMD/JMD mutants bind pertuzumab (Homo sapiens)
ERBB2 binds pertuzumab (Homo sapiens)
as a component of
ERBB2 R678Q:pertuzumab [plasma membrane] (Homo sapiens)
ERBB2:pertuzumab [plasma membrane] (Canis familiaris)
ERBB2:pertuzumab [plasma membrane] (Mus musculus)
ERBB2:pertuzumab [plasma membrane] (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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