| 27227380 |
Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development
Ren, L,
Yin, J,
Wang, W,
Robarge, K,
Liu, L,
Moffat, J,
Chan, J,
Moreno, D,
Chou, KJ,
Chen, H,
Merchant, M,
Gaudino, JJ,
Stults, J,
Blake, JF,
Grina, J,
Gould, SE,
Martinson, M,
Qin, A,
Belvin, M,
Sullivan, F,
Mueller, L,
Schwarz, JB,
Zhou, A,
Burkard, M,
Rasor, K,
Dudley, DA,
Diaz, D,
Orr, C,
Pacheco, P,
Hunsaker, T,
Shahidi-Latham, S
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J. Med. Chem. |
2016 |
