sorafenib [cytosol]

Stable Identifier
R-ALL-9657029
Type
ChemicalDrug
Compartment
cytosol
Icon
sorafenib [cytosol] icon
sorafenib [cytosol] icon
Locations in the PathwayBrowser
for Species:
Expand all
Literature References
PubMed ID Title Journal Year
15466206 BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

Rong, H, Shujath, J, Wilkie, D, Gedrich, R, Gawlak, S, Taylor, I, McHugh, M, Zhang, X, Lynch, M, Post, LE, Trail, PA, Tang, L, Eveleigh, D, Adnane, L, Riedl, B, Auclair, D, Rowley, B, Wilhelm, SM, Carter, C, McNabola, A, Cao, Y, Bollag, G, Chen, C, Liu, L, Vincent, P, Voznesensky, A

Cancer Res. 2004
External Reference Information
External Reference
sorafenib [Guide to Pharmacology:5711]
Participates
as an input of
as a member of
Disease
Name Identifier Synonyms
hepatocellular carcinoma DOID:684 adult Hepatoma, adult primary Liver carcinoma, Liver carcinoma, Hepatocellular carcinoma (morphologic abnormality), primary carcinoma of liver (disorder), hepatoma, Hepatoma, adult primary hepatocellular carcinoma, primary carcinoma of the liver cells, Hepatocellular carcinoma (clinical), Liver carcinoma, HCC, carcinoma of liver, specified as primary
thyroid cancer DOID:1781 Thyroid gland neoplasm, thyroid cancer, thyroid neoplasm, neoplasm of thyroid gland, thyroid neoplasm, Thyroid neoplasm, malignant tumour of thyroid gland, malignant neoplasm of thyroid gland
renal clear cell carcinoma DOID:4467 conventional renal cell carcinoma, Clear cell carcinoma of kidney (disorder), conventional (Clear cell) renal cell carcinoma
Cross References
ChEBI
Pharos - Ligands
PharmacoDB
Cite Us!