LY3009120 [cytosol]

Stable Identifier
R-ALL-9653105
Type
ChemicalDrug
Compartment
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
27999210 LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer

Blosser, W, Vakana, E, Simpson, N, Stancato, LF, Huber, L, Zhang, Y, Dowless, M, Manro, J, Pratt, S, Jaken, S, Stephens, J, Yuan, XJ, Peng, SB

Oncotarget 2017
26343583 Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers

McCann, D, Huber, L, Peng, SB, Webster, Y, Buchanan, S, Plowman, GD, Rutkoski, TJ, Vogeti, S, Smith, BD, Yadav, V, Flynn, DL, Ma, X, Kays, L, Patel, P, Yin, T, Zhang, Y, Chun, L, Walgren, J, Lu, WP, Gong, X, Kaufman, MD, Starling, JJ, Conti, I, Wise, S, Zhang, X, Van Horn, RD, Donoho, GP, Chen, SH, Mochalkin, I, Henry, JR

Cancer Cell 2015
External Reference Information
Participates
Disease
Name Identifier Synonyms
colorectal cancer DOID:9256
Cross References
ChEBI
PharmacoDB
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