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benazeprilat [extracellular region]
Stable Identifier
R-ALL-9614940
Type
ChemicalDrug
Compartment
extracellular region
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism of proteins (Bos taurus)
Peptide hormone metabolism (Bos taurus)
Metabolism of Angiotensinogen to Angiotensins (Bos taurus)
ACEIs bind ACE (Bos taurus)
ACEIs [extracellular region]
benazeprilat [extracellular region]
ACEIs:ACE(30-1232) [extracellular region] (Bos taurus)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Bos taurus)
ACEIs:ACE(30-1232) [extracellular region] (Bos taurus)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Metabolism of proteins (Caenorhabditis elegans)
Peptide hormone metabolism (Caenorhabditis elegans)
Metabolism of Angiotensinogen to Angiotensins (Caenorhabditis elegans)
ACEIs bind ACE (Caenorhabditis elegans)
ACEIs [extracellular region]
benazeprilat [extracellular region]
ACEIs:ACE(30-1232) [extracellular region] (Caenorhabditis elegans)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Caenorhabditis elegans)
ACEIs:ACE(30-1232) [extracellular region] (Caenorhabditis elegans)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Metabolism of proteins (Canis familiaris)
Peptide hormone metabolism (Canis familiaris)
Metabolism of Angiotensinogen to Angiotensins (Canis familiaris)
ACEIs bind ACE (Canis familiaris)
ACEIs [extracellular region]
benazeprilat [extracellular region]
ACEIs:ACE(30-1232) [extracellular region] (Canis familiaris)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Canis familiaris)
ACEIs:ACE(30-1232) [extracellular region] (Canis familiaris)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Metabolism of proteins (Drosophila melanogaster)
Peptide hormone metabolism (Drosophila melanogaster)
Metabolism of Angiotensinogen to Angiotensins (Drosophila melanogaster)
ACEIs bind ACE (Drosophila melanogaster)
ACEIs [extracellular region]
benazeprilat [extracellular region]
ACEIs:ACE(30-1232) [extracellular region] (Drosophila melanogaster)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Drosophila melanogaster)
ACEIs:ACE(30-1232) [extracellular region] (Drosophila melanogaster)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Metabolism of proteins (Gallus gallus)
Peptide hormone metabolism (Gallus gallus)
Metabolism of Angiotensinogen to Angiotensins (Gallus gallus)
ACEIs bind ACE (Gallus gallus)
ACEIs [extracellular region]
benazeprilat [extracellular region]
ACEIs:ACE(30-1232) [extracellular region] (Gallus gallus)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Gallus gallus)
ACEIs:ACE(30-1232) [extracellular region] (Gallus gallus)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Metabolism of proteins (Homo sapiens)
Peptide hormone metabolism (Homo sapiens)
Metabolism of Angiotensinogen to Angiotensins (Homo sapiens)
ACEIs bind ACE (Homo sapiens)
ACEIs [extracellular region]
benazeprilat [extracellular region]
ACEIs:ACE(30-1232) [extracellular region] (Homo sapiens)
ACEIs [extracellular region]
benazeprilat [extracellular region]
ACEIs translocate from ER lumen to extracellular region (Homo sapiens)
hydrolysed ACEIs [extracellular region]
benazeprilat [extracellular region]
Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Homo sapiens)
ACEIs:ACE(30-1232) [extracellular region] (Homo sapiens)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Metabolism of proteins (Mus musculus)
Peptide hormone metabolism (Mus musculus)
Metabolism of Angiotensinogen to Angiotensins (Mus musculus)
ACEIs bind ACE (Mus musculus)
ACEIs [extracellular region]
benazeprilat [extracellular region]
ACEIs:ACE(30-1232) [extracellular region] (Mus musculus)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Mus musculus)
ACEIs:ACE(30-1232) [extracellular region] (Mus musculus)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Metabolism of proteins (Rattus norvegicus)
Peptide hormone metabolism (Rattus norvegicus)
Metabolism of Angiotensinogen to Angiotensins (Rattus norvegicus)
ACEIs bind ACE (Rattus norvegicus)
ACEIs [extracellular region]
benazeprilat [extracellular region]
ACEIs:ACE(30-1232) [extracellular region] (Rattus norvegicus)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Rattus norvegicus)
ACEIs:ACE(30-1232) [extracellular region] (Rattus norvegicus)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Metabolism of proteins (Sus scrofa)
Peptide hormone metabolism (Sus scrofa)
Metabolism of Angiotensinogen to Angiotensins (Sus scrofa)
ACEIs bind ACE (Sus scrofa)
ACEIs [extracellular region]
benazeprilat [extracellular region]
ACEIs:ACE(30-1232) [extracellular region] (Sus scrofa)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Sus scrofa)
ACEIs:ACE(30-1232) [extracellular region] (Sus scrofa)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Metabolism of proteins (Xenopus tropicalis)
Peptide hormone metabolism (Xenopus tropicalis)
Metabolism of Angiotensinogen to Angiotensins (Xenopus tropicalis)
ACEIs bind ACE (Xenopus tropicalis)
ACEIs [extracellular region]
benazeprilat [extracellular region]
ACEIs:ACE(30-1232) [extracellular region] (Xenopus tropicalis)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Xenopus tropicalis)
ACEIs:ACE(30-1232) [extracellular region] (Xenopus tropicalis)
ACEIs [extracellular region]
benazeprilat [extracellular region]
Literature References
PubMed ID
Title
Journal
Year
1893642
The pharmacokinetics of benazepril relative to other ACE inhibitors
Gengo, FM
,
Brady, E
Clin Cardiol
1991
1720384
Benazepril. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in hypertension and congestive heart failure
Balfour, JA
,
Goa, KL
Drugs
1991
External Reference Information
External Reference
benazeprilat [Guide to Pharmacology:6375]
Participates
as a member of
hydrolysed ACEIs [extracellular region]
ACEIs [extracellular region]
Other forms of this molecule
benazeprilat [endoplasmic reticulum lumen]
Disease
Name
Identifier
Synonyms
myocardial infarction
DOID:5844
heart attack, Myocardial infarct
hypertension
DOID:10763
High blood pressure (& [essential hypertension]), HTN, hypertensive disease, hyperpiesia, vascular hypertensive disorder
congestive heart failure
DOID:6000
CHF, Cardiac Failure Congestive, Weak heart, Congestive heart disease
Cross References
ChEBI
88200
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