Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
ticlopidine [extracellular region]
Stable Identifier
R-ALL-9611258
Type
ChemicalDrug
Compartment
extracellular region
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Hemostasis (Bos taurus)
Platelet activation, signaling and aggregation (Bos taurus)
Signal amplification (Bos taurus)
ADP signalling through P2Y purinoceptor 12 (Bos taurus)
P2RY12 binds ADP (Bos taurus)
P2RY12:P2RY12 antagonists [plasma membrane] (Bos taurus)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
Signal Transduction (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR ligand binding (Bos taurus)
Class A/1 (Rhodopsin-like receptors) (Bos taurus)
Nucleotide-like (purinergic) receptors (Bos taurus)
P2Y receptors (Bos taurus)
P2RY12 binds ADP (Bos taurus)
P2RY12:P2RY12 antagonists [plasma membrane] (Bos taurus)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
P2RY12 binds P2RY12 antagonists (Bos taurus)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
P2RY12:P2RY12 antagonists [plasma membrane] (Bos taurus)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
Hemostasis (Canis familiaris)
Platelet activation, signaling and aggregation (Canis familiaris)
Signal amplification (Canis familiaris)
ADP signalling through P2Y purinoceptor 12 (Canis familiaris)
P2RY12 binds ADP (Canis familiaris)
P2RY12:P2RY12 antagonists [plasma membrane] (Canis familiaris)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
Signal Transduction (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR ligand binding (Canis familiaris)
Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
Nucleotide-like (purinergic) receptors (Canis familiaris)
P2Y receptors (Canis familiaris)
P2RY12 binds ADP (Canis familiaris)
P2RY12:P2RY12 antagonists [plasma membrane] (Canis familiaris)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
P2RY12 binds P2RY12 antagonists (Canis familiaris)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
P2RY12:P2RY12 antagonists [plasma membrane] (Canis familiaris)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
Hemostasis (Danio rerio)
Platelet activation, signaling and aggregation (Danio rerio)
Signal amplification (Danio rerio)
ADP signalling through P2Y purinoceptor 12 (Danio rerio)
P2RY12 binds ADP (Danio rerio)
P2RY12:P2RY12 antagonists [plasma membrane] (Danio rerio)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
Signal Transduction (Danio rerio)
Signaling by GPCR (Danio rerio)
GPCR ligand binding (Danio rerio)
Class A/1 (Rhodopsin-like receptors) (Danio rerio)
Nucleotide-like (purinergic) receptors (Danio rerio)
P2Y receptors (Danio rerio)
P2RY12 binds ADP (Danio rerio)
P2RY12:P2RY12 antagonists [plasma membrane] (Danio rerio)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
P2RY12 binds P2RY12 antagonists (Danio rerio)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
P2RY12:P2RY12 antagonists [plasma membrane] (Danio rerio)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Signal amplification (Homo sapiens)
ADP signalling through P2Y purinoceptor 12 (Homo sapiens)
P2RY12 binds ADP (Homo sapiens)
P2RY12:P2RY12 antagonists [plasma membrane] (Homo sapiens)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Nucleotide-like (purinergic) receptors (Homo sapiens)
P2Y receptors (Homo sapiens)
P2RY12 binds ADP (Homo sapiens)
P2RY12:P2RY12 antagonists [plasma membrane] (Homo sapiens)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
P2RY12 binds P2RY12 antagonists (Homo sapiens)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
P2RY12:P2RY12 antagonists [plasma membrane] (Homo sapiens)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
Hemostasis (Mus musculus)
Platelet activation, signaling and aggregation (Mus musculus)
Signal amplification (Mus musculus)
ADP signalling through P2Y purinoceptor 12 (Mus musculus)
P2RY12 binds ADP (Mus musculus)
P2RY12:P2RY12 antagonists [plasma membrane] (Mus musculus)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
Signal Transduction (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR ligand binding (Mus musculus)
Class A/1 (Rhodopsin-like receptors) (Mus musculus)
Nucleotide-like (purinergic) receptors (Mus musculus)
P2Y receptors (Mus musculus)
P2RY12 binds ADP (Mus musculus)
P2RY12:P2RY12 antagonists [plasma membrane] (Mus musculus)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
P2RY12 binds P2RY12 antagonists (Mus musculus)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
P2RY12:P2RY12 antagonists [plasma membrane] (Mus musculus)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
Hemostasis (Rattus norvegicus)
Platelet activation, signaling and aggregation (Rattus norvegicus)
Signal amplification (Rattus norvegicus)
ADP signalling through P2Y purinoceptor 12 (Rattus norvegicus)
P2RY12 binds ADP (Rattus norvegicus)
P2RY12:P2RY12 antagonists [plasma membrane] (Rattus norvegicus)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
Signal Transduction (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR ligand binding (Rattus norvegicus)
Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
Nucleotide-like (purinergic) receptors (Rattus norvegicus)
P2Y receptors (Rattus norvegicus)
P2RY12 binds ADP (Rattus norvegicus)
P2RY12:P2RY12 antagonists [plasma membrane] (Rattus norvegicus)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
P2RY12 binds P2RY12 antagonists (Rattus norvegicus)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
P2RY12:P2RY12 antagonists [plasma membrane] (Rattus norvegicus)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
Hemostasis (Sus scrofa)
Platelet activation, signaling and aggregation (Sus scrofa)
Signal amplification (Sus scrofa)
ADP signalling through P2Y purinoceptor 12 (Sus scrofa)
P2RY12 binds ADP (Sus scrofa)
P2RY12:P2RY12 antagonists [plasma membrane] (Sus scrofa)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
Signal Transduction (Sus scrofa)
Signaling by GPCR (Sus scrofa)
GPCR ligand binding (Sus scrofa)
Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
Nucleotide-like (purinergic) receptors (Sus scrofa)
P2Y receptors (Sus scrofa)
P2RY12 binds ADP (Sus scrofa)
P2RY12:P2RY12 antagonists [plasma membrane] (Sus scrofa)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
P2RY12 binds P2RY12 antagonists (Sus scrofa)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
P2RY12:P2RY12 antagonists [plasma membrane] (Sus scrofa)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
Hemostasis (Xenopus tropicalis)
Platelet activation, signaling and aggregation (Xenopus tropicalis)
Signal amplification (Xenopus tropicalis)
ADP signalling through P2Y purinoceptor 12 (Xenopus tropicalis)
P2RY12 binds ADP (Xenopus tropicalis)
P2RY12:P2RY12 antagonists [plasma membrane] (Xenopus tropicalis)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
Signal Transduction (Xenopus tropicalis)
Signaling by GPCR (Xenopus tropicalis)
GPCR ligand binding (Xenopus tropicalis)
Class A/1 (Rhodopsin-like receptors) (Xenopus tropicalis)
Nucleotide-like (purinergic) receptors (Xenopus tropicalis)
P2Y receptors (Xenopus tropicalis)
P2RY12 binds ADP (Xenopus tropicalis)
P2RY12:P2RY12 antagonists [plasma membrane] (Xenopus tropicalis)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
P2RY12 binds P2RY12 antagonists (Xenopus tropicalis)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
P2RY12:P2RY12 antagonists [plasma membrane] (Xenopus tropicalis)
P2RY12 antagonists [extracellular region]
ticlopidine [extracellular region]
Literature References
PubMed ID
Title
Journal
Year
8720746
Ticlopidine. A review of its pharmacology, clinical efficacy and tolerability in the prevention of cerebral ischaemia and stroke
Goa, KL
,
Noble, S
Drugs Aging
1996
3304967
Ticlopidine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in platelet-dependent disease states
Ward, A
,
Saltiel, E
Drugs
1987
External Reference Information
External Reference
ticlopidine [Guide to Pharmacology:7307]
Participates
as a member of
P2RY12 antagonists [extracellular region]
Disease
Name
Identifier
Synonyms
myocardial infarction
DOID:5844
heart attack, Myocardial infarct
cardiovascular system disease
DOID:1287
disease of subdivision of hemolymphoid system
cerebrovascular disease
DOID:6713
Cerebrovascular accident, stroke, cerebrovascular accident, cerebrovascular disorder, CVA
Cross References
ChEBI
9588
Pharos - Ligands
DJTFBY3F8FKR
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
