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What is Reactome ?
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Team
Scientific Advisory Board
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Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
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Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
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ReactomeFIViz
Developer's Zone
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Icon Info
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Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
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Overlays
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(4Fe-4S)(2+) [cytosol]
Stable Identifier
R-ALL-937126
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
tetra-mu3-sulfido-tetrairon(2+)
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Molybdenum cofactor biosynthesis (Bos taurus)
Cyclisation of GTP to precursor Z (Bos taurus)
holo-MOCS1 [cytosol] (Bos taurus)
(4Fe-4S)(2+) [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Bos taurus)
AOX1 oxidises PXL to PDXate (Bos taurus)
2xAOX1:cofactors [cytosol] (Bos taurus)
AOX1:cofactors [cytosol] (Bos taurus)
(4Fe-4S)(2+) [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Molybdenum cofactor biosynthesis (Caenorhabditis elegans)
Cyclisation of GTP to precursor Z (Caenorhabditis elegans)
holo-MOCS1 [cytosol] (Caenorhabditis elegans)
(4Fe-4S)(2+) [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Caenorhabditis elegans)
AOX1 oxidises PXL to PDXate (Caenorhabditis elegans)
2xAOX1:cofactors [cytosol] (Caenorhabditis elegans)
AOX1:cofactors [cytosol] (Caenorhabditis elegans)
(4Fe-4S)(2+) [cytosol]
Metabolism (Canis familiaris)
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Molybdenum cofactor biosynthesis (Canis familiaris)
Cyclisation of GTP to precursor Z (Canis familiaris)
holo-MOCS1 [cytosol] (Canis familiaris)
(4Fe-4S)(2+) [cytosol]
Metabolism (Danio rerio)
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of water-soluble vitamins and cofactors (Danio rerio)
Vitamin B6 activation to pyridoxal phosphate (Danio rerio)
AOX1 oxidises PXL to PDXate (Danio rerio)
2xAOX1:cofactors [cytosol] (Danio rerio)
AOX1:cofactors [cytosol] (Danio rerio)
(4Fe-4S)(2+) [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of water-soluble vitamins and cofactors (Dictyostelium discoideum)
Molybdenum cofactor biosynthesis (Dictyostelium discoideum)
Cyclisation of GTP to precursor Z (Dictyostelium discoideum)
holo-MOCS1 [cytosol] (Dictyostelium discoideum)
(4Fe-4S)(2+) [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Dictyostelium discoideum)
AOX1 oxidises PXL to PDXate (Dictyostelium discoideum)
2xAOX1:cofactors [cytosol] (Dictyostelium discoideum)
AOX1:cofactors [cytosol] (Dictyostelium discoideum)
(4Fe-4S)(2+) [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of water-soluble vitamins and cofactors (Drosophila melanogaster)
Molybdenum cofactor biosynthesis (Drosophila melanogaster)
Cyclisation of GTP to precursor Z (Drosophila melanogaster)
holo-MOCS1 [cytosol] (Drosophila melanogaster)
(4Fe-4S)(2+) [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Drosophila melanogaster)
AOX1 oxidises PXL to PDXate (Drosophila melanogaster)
2xAOX1:cofactors [cytosol] (Drosophila melanogaster)
AOX1:cofactors [cytosol] (Drosophila melanogaster)
(4Fe-4S)(2+) [cytosol]
Metabolism (Gallus gallus)
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of water-soluble vitamins and cofactors (Gallus gallus)
Molybdenum cofactor biosynthesis (Gallus gallus)
Cyclisation of GTP to precursor Z (Gallus gallus)
holo-MOCS1 [cytosol] (Gallus gallus)
(4Fe-4S)(2+) [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Gallus gallus)
AOX1 oxidises PXL to PDXate (Gallus gallus)
2xAOX1:cofactors [cytosol] (Gallus gallus)
AOX1:cofactors [cytosol] (Gallus gallus)
(4Fe-4S)(2+) [cytosol]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
Early SARS-CoV-2 Infection Events (Homo sapiens)
SARS-CoV-2 Genome Replication and Transcription (Homo sapiens)
Replication of the SARS-CoV-2 genome (Homo sapiens)
RTC binds SARS-CoV-2 genomic RNA complement (minus strand) (Homo sapiens)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
RTC completes synthesis of the minus strand genomic RNA complement (Homo sapiens)
SARS-CoV-2 gRNA:RTC:nascent RNA minus strand [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC:nascent RNA minus strand:RTC inhibitors [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC:nascent RNA minus strand [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 genomic RNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
RTC synthesizes SARS-CoV-2 plus strand genomic RNA (Homo sapiens)
SARS-CoV-2 gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA complement (minus strand):RTC:RTC inhibitors [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 genomic RNA (plus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
Replication transcription complex binds SARS-CoV-2 genomic RNA (Homo sapiens)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS coronavirus 2 gRNA with secondary structure:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA complement (minus strand):RTC binds RTC inhibitors (Homo sapiens)
SARS-CoV-2 gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA complement (minus strand):RTC:RTC inhibitors [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors (Homo sapiens)
SARS-CoV-2 gRNA:RTC:RNA primer [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC:RNA primer:RTC inhibitors [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC:RNA primer [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors (Homo sapiens)
SARS-CoV-2 gRNA:RTC:nascent RNA minus strand [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC:nascent RNA minus strand:RTC inhibitors [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC:nascent RNA minus strand [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp12 misincorporates a nucleotide in nascent RNA minus strand (Homo sapiens)
SARS coronavirus gRNA:RTC:nascent RNA minus strand with mismatched nucleotide [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC:RNA primer:RTC inhibitors [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC:RNA primer [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC:nascent RNA minus strand [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement (Homo sapiens)
SARS-CoV-2 gRNA:RTC:RNA primer [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC:RNA primer:RTC inhibitors [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC:RNA primer [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC:nascent RNA minus strand [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template (Homo sapiens)
SARS coronavirus 2 gRNA with secondary structure:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA (Homo sapiens)
SARS coronavirus gRNA:RTC:nascent RNA minus strand with mismatched nucleotide [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC:nascent RNA minus strand [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA (plus strand) (Homo sapiens)
SARS-CoV-2 genomic RNA (plus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
m7GpppA-capped SARS-CoV-2 genomic RNA (plus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) (Homo sapiens)
SARS-CoV-2 genomic RNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
m7GpppA-capped SARS-CoV-2 genomic RNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp15 cleaves viral poly(U)-RNA (Homo sapiens)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS coronavirus gRNA with secondary structure:RTC:nascent RNA minus strand [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS coronavirus 2 gRNA with secondary structure:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 dsRNA with poly(U)-containing (-) strand:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 5'-poly(U)-gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC: 5'-poly(U) RNA minus strand [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA (plus strand) (Homo sapiens)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
m7GpppA-capped SARS-CoV-2 genomic RNA (plus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) (Homo sapiens)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
m7GpppA-capped SARS-CoV-2 genomic RNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp8 generates RNA primers (Homo sapiens)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC:RNA primer [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
Transcription of SARS-CoV-2 sgRNAs (Homo sapiens)
Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching (Homo sapiens)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 minus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
Synthesis of SARS-CoV-2 plus strand subgenomic mRNAs (Homo sapiens)
SARS-CoV-2 minus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 plus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs (Homo sapiens)
GpppA-SARS-CoV-2 plus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 plus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs (Homo sapiens)
GpppA-SARS-CoV-2 plus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 plus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
m7GpppA-SARS-CoV-2 plus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs (Homo sapiens)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
m7GpppA-SARS-CoV-2 plus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
Translation of Replicase and Assembly of the Replication Transcription Complex (Homo sapiens)
Assembly of the SARS-CoV-2 Replication-Transcription Complex (RTC) (Homo sapiens)
nsp12 binds nsp7 and nsp8 (Homo sapiens)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp13 binds nsp12 (Homo sapiens)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp14 binds nsp12 (Homo sapiens)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp15 binds nsp8 (Homo sapiens)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp3 binds to nsp7-8 and nsp12-16 (Homo sapiens)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
Maturation of replicase proteins (Homo sapiens)
nsp12 acquires Fe-S cluster cofactors (Homo sapiens)
ISCU:Fe4S4 [cytosol] (Homo sapiens)
(4Fe-4S)(2+) [cytosol]
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
CNBP binds SARS-CoV-2 G-rich RNA (Homo sapiens)
CNBP:SARS-CoV-2 G-rich RNA:RTC [double membrane vesicle viral factory outer membrane] (Homo sapiens)
SARS-CoV-2 G-rich RNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 G-rich RNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
DDX58 binds SARS-CoV-2 dsRNA intermediates (Homo sapiens)
SARS-CoV-2 dsRNA intermediates:DDX58 [double membrane vesicle viral factory outer membrane] (Homo sapiens)
SARS-CoV-2 gRNA:RTC:nascent RNA minus strand [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC:nascent RNA minus strand [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
IFIH1:TKFC binds SARS-CoV-2 dsRNA intermediates (Homo sapiens)
SARS-CoV-2 dsRNA intermediates:IFIH1 [double membrane vesicle viral factory outer membrane] (Homo sapiens)
SARS-CoV-2 dsRNA with poly(U)-containing (-) strand:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 5'-poly(U)-gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC: 5'-poly(U) RNA minus strand [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 dsRNA with poly(U)-containing (-) strand:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 5'-poly(U)-gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC: 5'-poly(U) RNA minus strand [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
LARP1 binds SARS-CoV-2 RNA (Homo sapiens)
LARP1:SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Homo sapiens)
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp7:nsp8:nsp12 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
(4Fe-4S)(2+) [cytosol]
Metabolism (Homo sapiens)
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Molybdenum cofactor biosynthesis (Homo sapiens)
Cyclisation of GTP to precursor Z (Homo sapiens)
holo-MOCS1 [cytosol] (Homo sapiens)
(4Fe-4S)(2+) [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Homo sapiens)
AOX1 oxidises PXL to PDXate (Homo sapiens)
2xAOX1:cofactors [cytosol] (Homo sapiens)
AOX1:cofactors [cytosol] (Homo sapiens)
(4Fe-4S)(2+) [cytosol]
Metabolism (Mus musculus)
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of water-soluble vitamins and cofactors (Mus musculus)
Molybdenum cofactor biosynthesis (Mus musculus)
Cyclisation of GTP to precursor Z (Mus musculus)
holo-MOCS1 [cytosol] (Mus musculus)
(4Fe-4S)(2+) [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Mus musculus)
AOX1 oxidises PXL to PDXate (Mus musculus)
2xAOX1:cofactors [cytosol] (Mus musculus)
AOX1:cofactors [cytosol] (Mus musculus)
(4Fe-4S)(2+) [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of water-soluble vitamins and cofactors (Rattus norvegicus)
Molybdenum cofactor biosynthesis (Rattus norvegicus)
Cyclisation of GTP to precursor Z (Rattus norvegicus)
holo-MOCS1 [cytosol] (Rattus norvegicus)
(4Fe-4S)(2+) [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Rattus norvegicus)
AOX1 oxidises PXL to PDXate (Rattus norvegicus)
2xAOX1:cofactors [cytosol] (Rattus norvegicus)
AOX1:cofactors [cytosol] (Rattus norvegicus)
(4Fe-4S)(2+) [cytosol]
Metabolism (Sus scrofa)
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of water-soluble vitamins and cofactors (Sus scrofa)
Molybdenum cofactor biosynthesis (Sus scrofa)
Cyclisation of GTP to precursor Z (Sus scrofa)
holo-MOCS1 [cytosol] (Sus scrofa)
(4Fe-4S)(2+) [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Sus scrofa)
AOX1 oxidises PXL to PDXate (Sus scrofa)
2xAOX1:cofactors [cytosol] (Sus scrofa)
AOX1:cofactors [cytosol] (Sus scrofa)
(4Fe-4S)(2+) [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of water-soluble vitamins and cofactors (Xenopus tropicalis)
Molybdenum cofactor biosynthesis (Xenopus tropicalis)
Cyclisation of GTP to precursor Z (Xenopus tropicalis)
holo-MOCS1 [cytosol] (Xenopus tropicalis)
(4Fe-4S)(2+) [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Xenopus tropicalis)
AOX1 oxidises PXL to PDXate (Xenopus tropicalis)
2xAOX1:cofactors [cytosol] (Xenopus tropicalis)
AOX1:cofactors [cytosol] (Xenopus tropicalis)
(4Fe-4S)(2+) [cytosol]
External Reference Information
External Reference
tetra-mu3-sulfido-tetrairon(2+) [ChEBI:33722]
Participates
as a component of
holo-MOCS1 [cytosol] (Caenorhabditis elegans)
holo-MOCS1 [cytosol] (Dictyostelium discoideum)
holo-MOCS1 [cytosol] (Drosophila melanogaster)
holo-MOCS1 [cytosol] (Canis familiaris)
holo-MOCS1 [cytosol] (Mus musculus)
holo-MOCS1 [cytosol] (Xenopus tropicalis)
holo-MOCS1 [cytosol] (Sus scrofa)
holo-MOCS1 [cytosol] (Rattus norvegicus)
holo-MOCS1 [cytosol] (Bos taurus)
holo-MOCS1 [cytosol] (Gallus gallus)
holo-MOCS1 [cytosol] (Homo sapiens)
AOX1:cofactors [cytosol] (Xenopus tropicalis)
AOX1:cofactors [cytosol] (Sus scrofa)
AOX1:cofactors [cytosol] (Gallus gallus)
AOX1:cofactors [cytosol] (Drosophila melanogaster)
AOX1:cofactors [cytosol] (Rattus norvegicus)
AOX1:cofactors [cytosol] (Danio rerio)
AOX1:cofactors [cytosol] (Dictyostelium discoideum)
AOX1:cofactors [cytosol] (Caenorhabditis elegans)
AOX1:cofactors [cytosol] (Mus musculus)
AOX1:cofactors [cytosol] (Bos taurus)
AOX1:cofactors [cytosol] (Homo sapiens)
ISCU:Fe4S4 [cytosol] (Homo sapiens)
nsp12:2Fe4S4 [cytosol] (Severe acute respiratory syndrome coronavirus 2)
Other forms of this molecule
(4Fe-4S)(2+) [cytosol]
Fe4S4(2+) [cytoplasm]
(4Fe-4S)(2+) [mitochondrial matrix]
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