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FeHM [cytosol]
Stable Identifier
R-ALL-917795
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
ferriheme, ferriheme b
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Heme signaling (Bos taurus)
PGRMC2 binds Hemes (Bos taurus)
Hemes [cytosol]
FeHM [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Bos taurus)
Hemes [cytosol]
FeHM [cytosol]
XPO1:BACH1:Hemes are transported out of the nucleus (Bos taurus)
XPO1:BACH1:Hemes [cytosol] (Bos taurus)
BACH1:Hemes [cytosol] (Bos taurus)
Hemes [cytosol]
FeHM [cytosol]
Transport of small molecules (Bos taurus)
Iron uptake and transport (Bos taurus)
SLC46A1 transports hemes from extracellular region to cytosol (Bos taurus)
Hemes [cytosol]
FeHM [cytosol]
O2/CO2 exchange in erythrocytes (Bos taurus)
Erythrocytes take up carbon dioxide and release oxygen (Bos taurus)
CYB5Rs reduce MetHb to HbA (Bos taurus)
MetHb [cytosol] (Bos taurus)
Hemoglobin alpha:ferriheme b [cytosol] (Bos taurus)
FeHM [cytosol]
Hemoglobin beta:ferriheme b [cytosol] (Bos taurus)
FeHM [cytosol]
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Heme signaling (Caenorhabditis elegans)
PGRMC2 binds Hemes (Caenorhabditis elegans)
Hemes [cytosol]
FeHM [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Caenorhabditis elegans)
Hemes [cytosol]
FeHM [cytosol]
Transport of small molecules (Caenorhabditis elegans)
Iron uptake and transport (Caenorhabditis elegans)
SLC46A1 transports hemes from extracellular region to cytosol (Caenorhabditis elegans)
Hemes [cytosol]
FeHM [cytosol]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Heme signaling (Canis familiaris)
PGRMC2 binds Hemes (Canis familiaris)
Hemes [cytosol]
FeHM [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Canis familiaris)
Hemes [cytosol]
FeHM [cytosol]
XPO1:BACH1:Hemes are transported out of the nucleus (Canis familiaris)
XPO1:BACH1:Hemes [cytosol] (Canis familiaris)
BACH1:Hemes [cytosol] (Canis familiaris)
Hemes [cytosol]
FeHM [cytosol]
Transport of small molecules (Canis familiaris)
Iron uptake and transport (Canis familiaris)
SLC46A1 transports hemes from extracellular region to cytosol (Canis familiaris)
Hemes [cytosol]
FeHM [cytosol]
O2/CO2 exchange in erythrocytes (Canis familiaris)
Erythrocytes take up carbon dioxide and release oxygen (Canis familiaris)
CYB5Rs reduce MetHb to HbA (Canis familiaris)
MetHb [cytosol] (Canis familiaris)
Hemoglobin alpha:ferriheme b [cytosol] (Canis familiaris)
FeHM [cytosol]
Hemoglobin beta:ferriheme b [cytosol] (Canis familiaris)
FeHM [cytosol]
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Heme signaling (Danio rerio)
PGRMC2 binds Hemes (Danio rerio)
Hemes [cytosol]
FeHM [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Danio rerio)
Hemes [cytosol]
FeHM [cytosol]
Transport of small molecules (Danio rerio)
Iron uptake and transport (Danio rerio)
SLC46A1 transports hemes from extracellular region to cytosol (Danio rerio)
Hemes [cytosol]
FeHM [cytosol]
O2/CO2 exchange in erythrocytes (Danio rerio)
Erythrocytes take up carbon dioxide and release oxygen (Danio rerio)
CYB5Rs reduce MetHb to HbA (Danio rerio)
MetHb [cytosol] (Danio rerio)
Hemoglobin alpha:ferriheme b [cytosol] (Danio rerio)
FeHM [cytosol]
Hemoglobin beta:ferriheme b [cytosol] (Danio rerio)
FeHM [cytosol]
Cellular responses to stimuli (Dictyostelium discoideum)
Cellular responses to stress (Dictyostelium discoideum)
Heme signaling (Dictyostelium discoideum)
PGRMC2 binds Hemes (Dictyostelium discoideum)
Hemes [cytosol]
FeHM [cytosol]
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Heme signaling (Drosophila melanogaster)
PGRMC2 binds Hemes (Drosophila melanogaster)
Hemes [cytosol]
FeHM [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Drosophila melanogaster)
Hemes [cytosol]
FeHM [cytosol]
XPO1:BACH1:Hemes are transported out of the nucleus (Drosophila melanogaster)
XPO1:BACH1:Hemes [cytosol] (Drosophila melanogaster)
BACH1:Hemes [cytosol] (Drosophila melanogaster)
Hemes [cytosol]
FeHM [cytosol]
Transport of small molecules (Drosophila melanogaster)
Iron uptake and transport (Drosophila melanogaster)
SLC46A1 transports hemes from extracellular region to cytosol (Drosophila melanogaster)
Hemes [cytosol]
FeHM [cytosol]
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Heme signaling (Gallus gallus)
PGRMC2 binds Hemes (Gallus gallus)
Hemes [cytosol]
FeHM [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Gallus gallus)
Hemes [cytosol]
FeHM [cytosol]
XPO1:BACH1:Hemes are transported out of the nucleus (Gallus gallus)
XPO1:BACH1:Hemes [cytosol] (Gallus gallus)
BACH1:Hemes [cytosol] (Gallus gallus)
Hemes [cytosol]
FeHM [cytosol]
Transport of small molecules (Gallus gallus)
Iron uptake and transport (Gallus gallus)
SLC46A1 transports hemes from extracellular region to cytosol (Gallus gallus)
Hemes [cytosol]
FeHM [cytosol]
O2/CO2 exchange in erythrocytes (Gallus gallus)
Erythrocytes take up carbon dioxide and release oxygen (Gallus gallus)
CYB5Rs reduce MetHb to HbA (Gallus gallus)
MetHb [cytosol] (Gallus gallus)
Hemoglobin alpha:ferriheme b [cytosol] (Gallus gallus)
FeHM [cytosol]
Hemoglobin beta:ferriheme b [cytosol] (Gallus gallus)
FeHM [cytosol]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Heme signaling (Homo sapiens)
PGRMC2 binds Hemes (Homo sapiens)
Hemes [cytosol]
FeHM [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Homo sapiens)
Hemes [cytosol]
FeHM [cytosol]
XPO1:BACH1:Hemes are transported out of the nucleus (Homo sapiens)
XPO1:BACH1:Hemes [cytosol] (Homo sapiens)
BACH1:Hemes [cytosol] (Homo sapiens)
Hemes [cytosol]
FeHM [cytosol]
Response of EIF2AK1 (HRI) to heme deficiency (Homo sapiens)
Ferriheme dissociates from p-T-EIF2AK1:2xferriheme dimer (Homo sapiens)
FeHM [cytosol]
p-T-EIF2AK1:2xferriheme dimer [cytosol] (Homo sapiens)
p-T-EIF2AK1:2xferriheme [cytosol] (Homo sapiens)
FeHM [cytosol]
p-T-EIF2AK1:ferriheme dimer [cytosol] (Homo sapiens)
p-T-EIF2AK1:ferriheme [cytosol] (Homo sapiens)
FeHM [cytosol]
p-T,T486,T488-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha) (Homo sapiens)
p-T,T486,T488-EIF2AK1:ferriheme dimer [cytosol] (Homo sapiens)
p-T,T486,T488-EIF2AK1:ferriheme [cytosol] (Homo sapiens)
FeHM [cytosol]
p-T-EIF2AK1:ferriheme dimer autophosphorylates (Homo sapiens)
p-T,T486,T488-EIF2AK1:ferriheme dimer [cytosol] (Homo sapiens)
p-T,T486,T488-EIF2AK1:ferriheme [cytosol] (Homo sapiens)
FeHM [cytosol]
p-T-EIF2AK1:ferriheme dimer [cytosol] (Homo sapiens)
p-T-EIF2AK1:ferriheme [cytosol] (Homo sapiens)
FeHM [cytosol]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Infection with Mycobacterium tuberculosis (Homo sapiens)
Latent infection - Other responses of Mtb to phagocytosis (Homo sapiens)
Tolerance by Mtb to nitric oxide produced by macrophages (Homo sapiens)
Nitric oxide is oxidized to nitrate (Homo sapiens)
GlbN:Ferriheme dimer [cytosol] (Mycobacterium tuberculosis)
FeHM [cytosol]
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
ROS and RNS production in phagocytes (Homo sapiens)
Nitric oxide oxidizes to nitrosyl ion (Homo sapiens)
FeHM [cytosol]
Transport of small molecules (Homo sapiens)
Iron uptake and transport (Homo sapiens)
SLC46A1 transports hemes from extracellular region to cytosol (Homo sapiens)
Hemes [cytosol]
FeHM [cytosol]
O2/CO2 exchange in erythrocytes (Homo sapiens)
Erythrocytes take up carbon dioxide and release oxygen (Homo sapiens)
CYB5Rs reduce MetHb to HbA (Homo sapiens)
MetHb [cytosol] (Homo sapiens)
Hemoglobin alpha:ferriheme b [cytosol] (Homo sapiens)
FeHM [cytosol]
Hemoglobin beta:ferriheme b [cytosol] (Homo sapiens)
FeHM [cytosol]
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Heme signaling (Mus musculus)
PGRMC2 binds Hemes (Mus musculus)
Hemes [cytosol]
FeHM [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Mus musculus)
Hemes [cytosol]
FeHM [cytosol]
XPO1:BACH1:Hemes are transported out of the nucleus (Mus musculus)
XPO1:BACH1:Hemes [cytosol] (Mus musculus)
BACH1:Hemes [cytosol] (Mus musculus)
Hemes [cytosol]
FeHM [cytosol]
Transport of small molecules (Mus musculus)
Iron uptake and transport (Mus musculus)
SLC46A1 transports hemes from extracellular region to cytosol (Mus musculus)
Hemes [cytosol]
FeHM [cytosol]
O2/CO2 exchange in erythrocytes (Mus musculus)
Erythrocytes take up carbon dioxide and release oxygen (Mus musculus)
CYB5Rs reduce MetHb to HbA (Mus musculus)
MetHb [cytosol] (Mus musculus)
Hemoglobin alpha:ferriheme b [cytosol] (Mus musculus)
FeHM [cytosol]
Hemoglobin beta:ferriheme b [cytosol] (Mus musculus)
FeHM [cytosol]
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Heme signaling (Rattus norvegicus)
PGRMC2 binds Hemes (Rattus norvegicus)
Hemes [cytosol]
FeHM [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Rattus norvegicus)
Hemes [cytosol]
FeHM [cytosol]
XPO1:BACH1:Hemes are transported out of the nucleus (Rattus norvegicus)
XPO1:BACH1:Hemes [cytosol] (Rattus norvegicus)
BACH1:Hemes [cytosol] (Rattus norvegicus)
Hemes [cytosol]
FeHM [cytosol]
Transport of small molecules (Rattus norvegicus)
Iron uptake and transport (Rattus norvegicus)
SLC46A1 transports hemes from extracellular region to cytosol (Rattus norvegicus)
Hemes [cytosol]
FeHM [cytosol]
O2/CO2 exchange in erythrocytes (Rattus norvegicus)
Erythrocytes take up carbon dioxide and release oxygen (Rattus norvegicus)
CYB5Rs reduce MetHb to HbA (Rattus norvegicus)
MetHb [cytosol] (Rattus norvegicus)
Hemoglobin alpha:ferriheme b [cytosol] (Rattus norvegicus)
FeHM [cytosol]
Hemoglobin beta:ferriheme b [cytosol] (Rattus norvegicus)
FeHM [cytosol]
Cellular responses to stimuli (Saccharomyces cerevisiae)
Cellular responses to stress (Saccharomyces cerevisiae)
Heme signaling (Saccharomyces cerevisiae)
PGRMC2 binds Hemes (Saccharomyces cerevisiae)
Hemes [cytosol]
FeHM [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Saccharomyces cerevisiae)
Hemes [cytosol]
FeHM [cytosol]
Transport of small molecules (Saccharomyces cerevisiae)
Iron uptake and transport (Saccharomyces cerevisiae)
SLC46A1 transports hemes from extracellular region to cytosol (Saccharomyces cerevisiae)
Hemes [cytosol]
FeHM [cytosol]
Cellular responses to stimuli (Schizosaccharomyces pombe)
Cellular responses to stress (Schizosaccharomyces pombe)
Heme signaling (Schizosaccharomyces pombe)
PGRMC2 binds Hemes (Schizosaccharomyces pombe)
Hemes [cytosol]
FeHM [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Schizosaccharomyces pombe)
Hemes [cytosol]
FeHM [cytosol]
Transport of small molecules (Schizosaccharomyces pombe)
Iron uptake and transport (Schizosaccharomyces pombe)
SLC46A1 transports hemes from extracellular region to cytosol (Schizosaccharomyces pombe)
Hemes [cytosol]
FeHM [cytosol]
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Heme signaling (Sus scrofa)
PGRMC2 binds Hemes (Sus scrofa)
Hemes [cytosol]
FeHM [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Sus scrofa)
Hemes [cytosol]
FeHM [cytosol]
XPO1:BACH1:Hemes are transported out of the nucleus (Sus scrofa)
XPO1:BACH1:Hemes [cytosol] (Sus scrofa)
BACH1:Hemes [cytosol] (Sus scrofa)
Hemes [cytosol]
FeHM [cytosol]
Transport of small molecules (Sus scrofa)
Iron uptake and transport (Sus scrofa)
SLC46A1 transports hemes from extracellular region to cytosol (Sus scrofa)
Hemes [cytosol]
FeHM [cytosol]
O2/CO2 exchange in erythrocytes (Sus scrofa)
Erythrocytes take up carbon dioxide and release oxygen (Sus scrofa)
CYB5Rs reduce MetHb to HbA (Sus scrofa)
MetHb [cytosol] (Sus scrofa)
Hemoglobin alpha:ferriheme b [cytosol] (Sus scrofa)
FeHM [cytosol]
Hemoglobin beta:ferriheme b [cytosol] (Sus scrofa)
FeHM [cytosol]
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Heme signaling (Xenopus tropicalis)
SLC46A1 transports hemes from extracellular region to cytosol (Xenopus tropicalis)
Hemes [cytosol]
FeHM [cytosol]
Transport of small molecules (Xenopus tropicalis)
Iron uptake and transport (Xenopus tropicalis)
SLC46A1 transports hemes from extracellular region to cytosol (Xenopus tropicalis)
Hemes [cytosol]
FeHM [cytosol]
O2/CO2 exchange in erythrocytes (Xenopus tropicalis)
Erythrocytes take up carbon dioxide and release oxygen (Xenopus tropicalis)
CYB5Rs reduce MetHb to HbA (Xenopus tropicalis)
MetHb [cytosol] (Xenopus tropicalis)
Hemoglobin alpha:ferriheme b [cytosol] (Xenopus tropicalis)
FeHM [cytosol]
Hemoglobin beta:ferriheme b [cytosol] (Xenopus tropicalis)
FeHM [cytosol]
External Reference Information
External Reference
ferriheme b [ChEBI:36144]
Participates
as a component of
Hemoglobin beta:ferriheme b [cytosol] (Danio rerio)
Hemoglobin beta:ferriheme b [cytosol] (Gallus gallus)
Hemoglobin beta:ferriheme b [cytosol] (Rattus norvegicus)
Hemoglobin beta:ferriheme b [cytosol] (Sus scrofa)
Hemoglobin beta:ferriheme b [cytosol] (Bos taurus)
Hemoglobin beta:ferriheme b [cytosol] (Xenopus tropicalis)
Hemoglobin beta:ferriheme b [cytosol] (Mus musculus)
Hemoglobin beta:ferriheme b [cytosol] (Canis familiaris)
Hemoglobin beta:ferriheme b [cytosol] (Homo sapiens)
Hemoglobin alpha:ferriheme b [cytosol] (Gallus gallus)
Hemoglobin alpha:ferriheme b [cytosol] (Sus scrofa)
Hemoglobin alpha:ferriheme b [cytosol] (Rattus norvegicus)
Hemoglobin alpha:ferriheme b [cytosol] (Bos taurus)
Hemoglobin alpha:ferriheme b [cytosol] (Xenopus tropicalis)
Hemoglobin alpha:ferriheme b [cytosol] (Mus musculus)
Hemoglobin alpha:ferriheme b [cytosol] (Canis familiaris)
Hemoglobin alpha:ferriheme b [cytosol] (Danio rerio)
Hemoglobin alpha:ferriheme b [cytosol] (Homo sapiens)
p-T,T483,T485-Eif2ak1:ferriheme [cytosol] (Mus musculus)
p-T-Eif2ak1:ferriheme [cytosol] (Mus musculus)
p-T-Eif2ak1:2xferriheme [cytosol] (Mus musculus)
p-T-EIF2AK1:ferriheme [cytosol] (Oryctolagus cuniculus)
p-T-EIF2AK1:2xferriheme [cytosol] (Oryctolagus cuniculus)
p-T-EIF2AK1:2xferriheme [cytosol] (Homo sapiens)
p-T-EIF2AK1:ferriheme [cytosol] (Homo sapiens)
p-T,T486,T488-EIF2AK1:ferriheme [cytosol] (Homo sapiens)
GlbN:Ferriheme dimer [cytosol] (Mycobacterium tuberculosis)
as an output of
Ferriheme dissociates from p-T-Eif2ak1:2xferriheme dimer (Mus musculus)
Ferriheme dissociates from p-T-EIF2AK1:2xferriheme dimer (Oryctolagus cuniculus)
Ferriheme dissociates from p-T-EIF2AK1:2xferriheme dimer (Homo sapiens)
as an input of
Nitric oxide oxidizes to nitrosyl ion (Homo sapiens)
as a candidate of
Hemes [cytosol]
Other forms of this molecule
FeHM [mitochondrial outer membrane]
ferriheme b [endocytic vesicle lumen]
FeHM [nuclear envelope]
FeHM [extracellular region]
ferriheme b [nucleoplasm]
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