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Cu2+ [plasma membrane]
Stable Identifier
R-ALL-904823
Type
Chemical Compound [SimpleEntity]
Compartment
plasma membrane
Synonyms
Copper, copper atom
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
AOC1 deaminates Hist (Bos taurus)
AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Bos taurus)
Cu2+ [plasma membrane]
AOC3 deaminates BZAM (Bos taurus)
AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane] (Bos taurus)
Cu2+ [plasma membrane]
Transport of small molecules (Bos taurus)
Iron uptake and transport (Bos taurus)
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Bos taurus)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Bos taurus)
Cu2+ [plasma membrane]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Bos taurus)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Bos taurus)
Cu2+ [plasma membrane]
SLC-mediated transmembrane transport (Bos taurus)
Transport of bile salts and organic acids, metal ions and amine compounds (Bos taurus)
Metal ion SLC transporters (Bos taurus)
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Bos taurus)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Bos taurus)
Cu2+ [plasma membrane]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
AOC3 deaminates BZAM (Canis familiaris)
AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane] (Canis familiaris)
Cu2+ [plasma membrane]
Transport of small molecules (Canis familiaris)
Iron uptake and transport (Canis familiaris)
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Canis familiaris)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Canis familiaris)
Cu2+ [plasma membrane]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Canis familiaris)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Canis familiaris)
Cu2+ [plasma membrane]
SLC-mediated transmembrane transport (Canis familiaris)
Transport of bile salts and organic acids, metal ions and amine compounds (Canis familiaris)
Metal ion SLC transporters (Canis familiaris)
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Canis familiaris)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Canis familiaris)
Cu2+ [plasma membrane]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase I - Functionalization of compounds (Danio rerio)
AOC1 deaminates Hist (Danio rerio)
AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Danio rerio)
Cu2+ [plasma membrane]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
AOC1 deaminates Hist (Gallus gallus)
AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Gallus gallus)
Cu2+ [plasma membrane]
AOC3 deaminates BZAM (Gallus gallus)
AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane] (Gallus gallus)
Cu2+ [plasma membrane]
Transport of small molecules (Gallus gallus)
Iron uptake and transport (Gallus gallus)
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Gallus gallus)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Gallus gallus)
Cu2+ [plasma membrane]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Gallus gallus)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Gallus gallus)
Cu2+ [plasma membrane]
SLC-mediated transmembrane transport (Gallus gallus)
Transport of bile salts and organic acids, metal ions and amine compounds (Gallus gallus)
Metal ion SLC transporters (Gallus gallus)
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Gallus gallus)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Gallus gallus)
Cu2+ [plasma membrane]
Disease (Homo sapiens)
Disorders of transmembrane transporters (Homo sapiens)
SLC transporter disorders (Homo sapiens)
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) (Homo sapiens)
Defective SLC40A1 does not transport Fe3+ from extracellular region to cytosol (Homo sapiens)
HEPH:6xCu2+:SLC40A1 mutants [plasma membrane] (Homo sapiens)
Cu2+ [plasma membrane]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
AOC1 deaminates Hist (Homo sapiens)
AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Homo sapiens)
Cu2+ [plasma membrane]
AOC3 deaminates BZAM (Homo sapiens)
AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane] (Homo sapiens)
Cu2+ [plasma membrane]
Transport of small molecules (Homo sapiens)
Iron uptake and transport (Homo sapiens)
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Homo sapiens)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Homo sapiens)
Cu2+ [plasma membrane]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Homo sapiens)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Homo sapiens)
Cu2+ [plasma membrane]
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Metal ion SLC transporters (Homo sapiens)
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Homo sapiens)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Homo sapiens)
Cu2+ [plasma membrane]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
AOC1 deaminates Hist (Mus musculus)
AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Mus musculus)
Cu2+ [plasma membrane]
AOC3 deaminates BZAM (Mus musculus)
AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane] (Mus musculus)
Cu2+ [plasma membrane]
Transport of small molecules (Mus musculus)
Iron uptake and transport (Mus musculus)
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Mus musculus)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Mus musculus)
Cu2+ [plasma membrane]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Mus musculus)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Mus musculus)
Cu2+ [plasma membrane]
SLC-mediated transmembrane transport (Mus musculus)
Transport of bile salts and organic acids, metal ions and amine compounds (Mus musculus)
Metal ion SLC transporters (Mus musculus)
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Mus musculus)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Mus musculus)
Cu2+ [plasma membrane]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
AOC1 deaminates Hist (Rattus norvegicus)
AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Rattus norvegicus)
Cu2+ [plasma membrane]
AOC3 deaminates BZAM (Rattus norvegicus)
AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane] (Rattus norvegicus)
Cu2+ [plasma membrane]
Transport of small molecules (Rattus norvegicus)
Iron uptake and transport (Rattus norvegicus)
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Rattus norvegicus)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Rattus norvegicus)
Cu2+ [plasma membrane]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Rattus norvegicus)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Rattus norvegicus)
Cu2+ [plasma membrane]
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of bile salts and organic acids, metal ions and amine compounds (Rattus norvegicus)
Metal ion SLC transporters (Rattus norvegicus)
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Rattus norvegicus)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Rattus norvegicus)
Cu2+ [plasma membrane]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
AOC1 deaminates Hist (Sus scrofa)
AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Sus scrofa)
Cu2+ [plasma membrane]
AOC3 deaminates BZAM (Sus scrofa)
AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane] (Sus scrofa)
Cu2+ [plasma membrane]
Transport of small molecules (Sus scrofa)
Iron uptake and transport (Sus scrofa)
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Sus scrofa)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Sus scrofa)
Cu2+ [plasma membrane]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Sus scrofa)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Sus scrofa)
Cu2+ [plasma membrane]
SLC-mediated transmembrane transport (Sus scrofa)
Transport of bile salts and organic acids, metal ions and amine compounds (Sus scrofa)
Metal ion SLC transporters (Sus scrofa)
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Sus scrofa)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Sus scrofa)
Cu2+ [plasma membrane]
Metabolism (Xenopus tropicalis)
Biological oxidations (Xenopus tropicalis)
Phase I - Functionalization of compounds (Xenopus tropicalis)
AOC1 deaminates Hist (Xenopus tropicalis)
AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Xenopus tropicalis)
Cu2+ [plasma membrane]
AOC3 deaminates BZAM (Xenopus tropicalis)
AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane] (Xenopus tropicalis)
Cu2+ [plasma membrane]
Transport of small molecules (Xenopus tropicalis)
Iron uptake and transport (Xenopus tropicalis)
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Xenopus tropicalis)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Xenopus tropicalis)
Cu2+ [plasma membrane]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Xenopus tropicalis)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Xenopus tropicalis)
Cu2+ [plasma membrane]
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of bile salts and organic acids, metal ions and amine compounds (Xenopus tropicalis)
Metal ion SLC transporters (Xenopus tropicalis)
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Xenopus tropicalis)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Xenopus tropicalis)
Cu2+ [plasma membrane]
External Reference Information
External Reference
copper atom [ChEBI:28694]
Participates
as a component of
HEPH:6xCu2+:SLC40A1 mutants [plasma membrane] (Homo sapiens)
AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Xenopus tropicalis)
AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Danio rerio)
AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Sus scrofa)
AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Mus musculus)
AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Rattus norvegicus)
AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Gallus gallus)
AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Bos taurus)
AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Homo sapiens)
AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane] (Sus scrofa)
AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane] (Mus musculus)
AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane] (Bos taurus)
AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane] (Gallus gallus)
AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane] (Xenopus tropicalis)
AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane] (Rattus norvegicus)
AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane] (Canis familiaris)
AOC3 dimer:2xCu2+:4xCa2+ [plasma membrane] (Homo sapiens)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Sus scrofa)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Gallus gallus)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Rattus norvegicus)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Xenopus tropicalis)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Bos taurus)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Canis familiaris)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Homo sapiens)
SLC40A1:HEPH:6Cu2+ [plasma membrane] (Mus musculus)
Other forms of this molecule
Cu2+ [secretory granule lumen]
Cross References
COMPOUND
C00070
PubChem Substance
8144302
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