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VD3 [endoplasmic reticulum membrane]
Stable Identifier
R-ALL-8963870
Type
Chemical Compound [SimpleEntity]
Compartment
endoplasmic reticulum membrane
Synonyms
Vitamin D3, calciol, Cholecalciferol
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
Cytochrome P450 - arranged by substrate type (Bos taurus)
Vitamins (Bos taurus)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Bos taurus)
VD3 [endoplasmic reticulum membrane]
Metabolism of lipids (Bos taurus)
Metabolism of steroids (Bos taurus)
Vitamin D (calciferol) metabolism (Bos taurus)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Bos taurus)
VD3 [endoplasmic reticulum membrane]
Metabolism (Caenorhabditis elegans)
Biological oxidations (Caenorhabditis elegans)
Phase I - Functionalization of compounds (Caenorhabditis elegans)
Cytochrome P450 - arranged by substrate type (Caenorhabditis elegans)
Vitamins (Caenorhabditis elegans)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Caenorhabditis elegans)
VD3 [endoplasmic reticulum membrane]
Metabolism of lipids (Caenorhabditis elegans)
Metabolism of steroids (Caenorhabditis elegans)
Vitamin D (calciferol) metabolism (Caenorhabditis elegans)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Caenorhabditis elegans)
VD3 [endoplasmic reticulum membrane]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Cytochrome P450 - arranged by substrate type (Canis familiaris)
Vitamins (Canis familiaris)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Canis familiaris)
VD3 [endoplasmic reticulum membrane]
Metabolism of lipids (Canis familiaris)
Metabolism of steroids (Canis familiaris)
Vitamin D (calciferol) metabolism (Canis familiaris)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Canis familiaris)
VD3 [endoplasmic reticulum membrane]
Metabolism (Dictyostelium discoideum)
Biological oxidations (Dictyostelium discoideum)
Phase I - Functionalization of compounds (Dictyostelium discoideum)
Cytochrome P450 - arranged by substrate type (Dictyostelium discoideum)
Vitamins (Dictyostelium discoideum)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Dictyostelium discoideum)
VD3 [endoplasmic reticulum membrane]
Metabolism of lipids (Dictyostelium discoideum)
Metabolism of steroids (Dictyostelium discoideum)
Vitamin D (calciferol) metabolism (Dictyostelium discoideum)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Dictyostelium discoideum)
VD3 [endoplasmic reticulum membrane]
Metabolism (Drosophila melanogaster)
Biological oxidations (Drosophila melanogaster)
Phase I - Functionalization of compounds (Drosophila melanogaster)
Cytochrome P450 - arranged by substrate type (Drosophila melanogaster)
Vitamins (Drosophila melanogaster)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Drosophila melanogaster)
VD3 [endoplasmic reticulum membrane]
Metabolism of lipids (Drosophila melanogaster)
Metabolism of steroids (Drosophila melanogaster)
Vitamin D (calciferol) metabolism (Drosophila melanogaster)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Drosophila melanogaster)
VD3 [endoplasmic reticulum membrane]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
Cytochrome P450 - arranged by substrate type (Gallus gallus)
Vitamins (Gallus gallus)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Gallus gallus)
VD3 [endoplasmic reticulum membrane]
Metabolism of lipids (Gallus gallus)
Metabolism of steroids (Gallus gallus)
Vitamin D (calciferol) metabolism (Gallus gallus)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Gallus gallus)
VD3 [endoplasmic reticulum membrane]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Metabolic disorders of biological oxidation enzymes (Homo sapiens)
Defective CYP27B1 causes VDDR1B (Homo sapiens)
Defective CYP2R1 does not 25-hydroxylate vitamin D (Homo sapiens)
VD3 [endoplasmic reticulum membrane]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Cytochrome P450 - arranged by substrate type (Homo sapiens)
Vitamins (Homo sapiens)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Homo sapiens)
VD3 [endoplasmic reticulum membrane]
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Vitamin D (calciferol) metabolism (Homo sapiens)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Homo sapiens)
VD3 [endoplasmic reticulum membrane]
Photolytic cleavage and thermal isomerization of 7-dehydroCHOL (Homo sapiens)
VD3 [endoplasmic reticulum membrane]
VD3 translocates from ER membrane to extracellular region (Homo sapiens)
VD3 [endoplasmic reticulum membrane]
VD3 translocates from extracellular region to ER membrane (Homo sapiens)
VD3 [endoplasmic reticulum membrane]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Cytochrome P450 - arranged by substrate type (Mus musculus)
Vitamins (Mus musculus)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Mus musculus)
VD3 [endoplasmic reticulum membrane]
Metabolism of lipids (Mus musculus)
Metabolism of steroids (Mus musculus)
Vitamin D (calciferol) metabolism (Mus musculus)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Mus musculus)
VD3 [endoplasmic reticulum membrane]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
Cytochrome P450 - arranged by substrate type (Rattus norvegicus)
Vitamins (Rattus norvegicus)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Rattus norvegicus)
VD3 [endoplasmic reticulum membrane]
Metabolism of lipids (Rattus norvegicus)
Metabolism of steroids (Rattus norvegicus)
Vitamin D (calciferol) metabolism (Rattus norvegicus)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Rattus norvegicus)
VD3 [endoplasmic reticulum membrane]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
Cytochrome P450 - arranged by substrate type (Sus scrofa)
Vitamins (Sus scrofa)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Sus scrofa)
VD3 [endoplasmic reticulum membrane]
Metabolism of lipids (Sus scrofa)
Metabolism of steroids (Sus scrofa)
Vitamin D (calciferol) metabolism (Sus scrofa)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Sus scrofa)
VD3 [endoplasmic reticulum membrane]
Metabolism (Xenopus tropicalis)
Biological oxidations (Xenopus tropicalis)
Phase I - Functionalization of compounds (Xenopus tropicalis)
Cytochrome P450 - arranged by substrate type (Xenopus tropicalis)
Vitamins (Xenopus tropicalis)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Xenopus tropicalis)
VD3 [endoplasmic reticulum membrane]
Metabolism of lipids (Xenopus tropicalis)
Metabolism of steroids (Xenopus tropicalis)
Vitamin D (calciferol) metabolism (Xenopus tropicalis)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Xenopus tropicalis)
VD3 [endoplasmic reticulum membrane]
External Reference Information
External Reference
calciol [ChEBI:28940]
Participates
as an input of
Defective CYP2R1 does not 25-hydroxylate vitamin D (Homo sapiens)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Dictyostelium discoideum)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Caenorhabditis elegans)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Drosophila melanogaster)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Gallus gallus)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Xenopus tropicalis)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Sus scrofa)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Bos taurus)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Canis familiaris)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Rattus norvegicus)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Mus musculus)
VD3 translocates from ER membrane to extracellular region (Homo sapiens)
CYP2R1 25-hydroxylates VD3 to 25(OH)D (Homo sapiens)
as an output of
Photolytic cleavage and thermal isomerization of 7-dehydrocholesterol (Rattus norvegicus)
Photolytic cleavage and thermal isomerization of 7-dehydroCHOL (Homo sapiens)
VD3 translocates from extracellular region to ER membrane (Homo sapiens)
Other forms of this molecule
VD3 [extracellular region]
Cross References
COMPOUND
C05443
HMDB Metabolite
HMDB0000876
ZINC
ZINC000004474460
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![VD3 [endoplasmic reticulum membrane] icon](/icon/R-ICO-012561.svg){kind=icon}
